Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G(4)C(2) RNA in a cellular model

por Frottin, Frédéric, Pérez-Berlanga, Manuela, Hartl, F Ulrich, Hipp, Mark S
Publicado 2021

Sis1 potentiates the stress response to protein aggregation and elevated temperature

por Klaips, Courtney L., Gropp, Michael H. M., Hipp, Mark S., Hartl, F. Ulrich
Publicado 2020

Role for ribosome-associated quality control in sampling proteins for MHC class I-mediated antigen presentation

por Trentini, Débora Broch, Pecoraro, Matteo, Tiwary, Shivani, Cox, Jürgen, Mann, Matthias, Hipp, Mark S., Hartl, F. Ulrich
Publicado 2020

Indirect inhibition of 26S proteasome activity in a cellular model of Huntington’s disease

por Hipp, Mark S., Patel, Chetan N., Bersuker, Kirill, Riley, Brigit E., Kaiser, Stephen E., Shaler, Thomas A., Brandeis, Michael, Kopito, Ron R.
Publicado 2012

Spatiotemporal Proteomic Profiling of Huntington’s Disease Inclusions Reveals Widespread Loss of Protein Function

por Hosp, Fabian, Gutiérrez-Ángel, Sara, Schaefer, Martin H., Cox, Jürgen, Meissner, Felix, Hipp, Mark S., Hartl, F.-Ulrich, Klein, Rüdiger, Dudanova, Irina, Mann, Matthias
Publicado 2017

Plasticity-Related Gene 5 Is Expressed in a Late Phase of Neurodifferentiation After Neuronal Cell-Fate Determination

por Gross, Isabel, Brandt, Nicola, Vonk, Danara, Köper, Franziska, Wöhlbrand, Lars, Rabus, Ralf, Witt, Martin, Heep, Axel, Plösch, Torsten, Hipp, Mark S., Bräuer, Anja U.
Publicado 2022

Fluc‐EGFP reporter mice reveal differential alterations of neuronal proteostasis in aging and disease

por Blumenstock, Sonja, Schulz‐Trieglaff, Elena Katharina, Voelkl, Kerstin, Bolender, Anna‐Lena, Lapios, Paul, Lindner, Jana, Hipp, Mark S, Hartl, F Ulrich, Klein, Rüdiger, Dudanova, Irina
Publicado 2021

The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model

por Yuste-Checa, Patricia, Trinkaus, Victoria A., Riera-Tur, Irene, Imamoglu, Rahmi, Schaller, Theresa F., Wang, Huping, Dudanova, Irina, Hipp, Mark S., Bracher, Andreas, Hartl, F. Ulrich
Publicado 2021

In situ architecture of neuronal α-Synuclein inclusions

por Trinkaus, Victoria A., Riera-Tur, Irene, Martínez-Sánchez, Antonio, Bäuerlein, Felix J. B., Guo, Qiang, Arzberger, Thomas, Baumeister, Wolfgang, Dudanova, Irina, Hipp, Mark S., Hartl, F. Ulrich, Fernández-Busnadiego, Rubén
Publicado 2021

Gel‐like inclusions of C‐terminal fragments of TDP‐43 sequester stalled proteasomes in neurons

por Riemenschneider, Henrick, Guo, Qiang, Bader, Jakob, Frottin, Frédéric, Farny, Daniel, Kleinberger, Gernot, Haass, Christian, Mann, Matthias, Hartl, F. Ulrich, Baumeister, Wolfgang, Hipp, Mark S, Meissner, Felix, Fernández‐Busnadiego, Rubén, Edbauer, Dieter
Publicado 2022

Cell‐to‐cell transmission of C9orf72 poly‐(Gly‐Ala) triggers key features of ALS/FTD

por Khosravi, Bahram, LaClair, Kathrine D, Riemenschneider, Henrick, Zhou, Qihui, Frottin, Frédéric, Mareljic, Nikola, Czuppa, Mareike, Farny, Daniel, Hartmann, Hannelore, Michaelsen, Meike, Arzberger, Thomas, Hartl, F Ulrich, Hipp, Mark S, Edbauer, Dieter
Publicado 2020

Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selec...

por Riley, Brigit E., Kaiser, Stephen E., Shaler, Thomas A., Ng, Aylwin C.Y., Hara, Taichi, Hipp, Mark S., Lage, Kasper, Xavier, Ramnik J., Ryu, Kwon-Yul, Taguchi, Keiko, Yamamoto, Masayuki, Tanaka, Keiji, Mizushima, Noboru, Komatsu, Masaaki, Kopito, Ron R.
Publicado 2010

The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system

por Saha, Itika, Yuste-Checa, Patricia, Da Silva Padilha, Miguel, Guo, Qiang, Körner, Roman, Holthusen, Hauke, Trinkaus, Victoria A., Dudanova, Irina, Fernández-Busnadiego, Rubén, Baumeister, Wolfgang, Sanders, David W., Gautam, Saurabh, Diamond, Marc I., Hartl, F. Ulrich, Hipp, Mark S.
Publicado 2023