A High-Throughput Screen against Pantothenate Synthetase (PanC) Identifies 3-Biphenyl-4-Cyanopyrrole-2-Carboxylic Acids as a New Class of Inhibitor with Activity against Mycobacter...

por Kumar, Anuradha, Casey, Allen, Odingo, Joshua, Kesicki, Edward A., Abrahams, Garth, Vieth, Michal, Masquelin, Thierry, Mizrahi, Valerie, Hipskind, Philip A., Sherman, David R., Parish, Tanya
Publicado 2013

Imidazopyridine Compounds Inhibit Mycobacterial Growth by Depleting ATP Levels

por O'Malley, Theresa, Alling, Torey, Early, Julie V., Wescott, Heather A., Kumar, Anuradha, Moraski, Garrett C., Miller, Marvin J., Masquelin, Thierry, Hipskind, Philip A., Parish, Tanya
Publicado 2018

Identification of Compounds with pH-Dependent Bactericidal Activity against Mycobacterium tuberculosis

por Early, Julie, Ollinger, Juliane, Darby, Crystal, Alling, Torey, Mullen, Steven, Casey, Allen, Gold, Ben, Ochoada, Jason, Wiernicki, Todd, Masquelin, Thierry, Nathan, Carl, Hipskind, Philip A., Parish, Tanya
Publicado 2018

The synthesis and evaluation of triazolopyrimidines as anti-tubercular agents

por Zuniga, Edison S., Korkegian, Aaron, Mullen, Steven, Hembre, Erik J., Ornstein, Paul L., Cortez, Guillermo, Biswas, Kallolmay, Kumar, Naresh, Cramer, Jeffrey, Masquelin, Thierry, Hipskind, Philip A., Odingo, Joshua, Parish, Tanya
Publicado 2017

In Vitro Evaluation of Novel Nitazoxanide Derivatives against Mycobacterium tuberculosis

por Odingo, Joshua, Bailey, Mai A., Files, Megan, Early, Julie V., Alling, Torey, Dennison, Devon, Bowman, Julie, Dalai, Suryakanta, Kumar, Naresh, Cramer, Jeffrey, Masquelin, Thierry, Hipskind, Philip A., Parish, Tanya
Publicado 2017

Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents

por Kesicki, Edward A., Bailey, Mai A., Ovechkina, Yulia, Early, Julie V., Alling, Torey, Bowman, Julie, Zuniga, Edison S., Dalai, Suryakanta, Kumar, Naresh, Masquelin, Thierry, Hipskind, Philip A., Odingo, Joshua O., Parish, Tanya
Publicado 2016

Improved Phenoxyalkylbenzimidazoles with Activity against Mycobacterium tuberculosis Appear to Target QcrB

por Chandrasekera, N. Susantha, Berube, Bryan J., Shetye, Gauri, Chettiar, Somsundaram, O’Malley, Theresa, Manning, Alyssa, Flint, Lindsay, Awasthi, Divya, Ioerger, Thomas R., Sacchettini, James, Masquelin, Thierry, Hipskind, Philip A., Odingo, Joshua, Parish, Tanya
Publicado 2017

Novel Trifluoromethyl Pyrimidinone Compounds With Activity Against Mycobacterium tuberculosis

por Hembre, Erik, Early, Julie V., Odingo, Joshua, Shelton, Catherine, Anoshchenko, Olena, Guzman, Junitta, Flint, Lindsay, Dennison, Devon, McNeil, Matthew B., Korkegian, Aaron, Ovechkina, Yulia, Ornstein, Paul, Masquelin, Thierry, Hipskind, Philip A., Parish, Tanya
Publicado 2021

Spirocycle MmpL3 Inhibitors with Improved hERG and Cytotoxicity Profiles as Inhibitors of Mycobacterium tuberculosis Growth

por Ray, Peter C., Huggett, Margaret, Turner, Penelope A., Taylor, Malcolm, Cleghorn, Laura A. T., Early, Julie, Kumar, Anuradha, Bonnett, Shilah A., Flint, Lindsay, Joerss, Douglas, Johnson, James, Korkegian, Aaron, Mullen, Steven, Moure, Abraham L., Davis, Susan H., Murugesan, Dinakaran, Mathieson, Michael, Caldwell, Nicola, Engelhart, Curtis A., Schnappinger, Dirk, Epemolu, Ola, Zuccotto, Fabio, Riley, Jennifer, Scullion, Paul, Stojanovski, Laste, Massoudi, Lisa, Robertson, Gregory T., Lenaerts, Anne J., Freiberg, Gail, Kempf, Dale J., Masquelin, Thierry, Hipskind, Philip A., Odingo, Joshua, Read, Kevin D., Green, Simon R., Wyatt, Paul G., Parish, Tanya
Publicado 2021

Identification of β-Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions

por Gold, Ben, Zhang, Jun, Quezada, Landys Lopez, Roberts, Julia, Ling, Yan, Wood, Madeleine, Shinwari, Wasima, Goullieux, Laurent, Roubert, Christine, Fraisse, Laurent, Bacqué, Eric, Lagrange, Sophie, Filoche-Rommé, Bruno, Vieth, Michal, Hipskind, Philip A., Jungheim, Louis N., Aubé, Jeffrey, Scarry, Sarah M., McDonald, Stacey L., Li, Kelin, Perkowski, Andrew, Nguyen, Quyen, Dartois, Véronique, Zimmerman, Matthew, Olsen, David B., Young, Katherine, Bonnett, Shilah, Joerss, Douglas, Parish, Tanya, Boshoff, Helena I., Arora, Kriti, Barry, Clifton E., Guijarro, Laura, Anca, Sara, Rullas, Joaquín, Rodríguez-Salguero, Beatriz, Martínez-Martínez, Maria S., Porras-De Francisco, Esther, Cacho, Monica, Barros-Aguirre, David, Smith, Paul, Berthel, Steven J., Nathan, Carl, Bates, Robert H.
Publicado 2022