Dose- and LET-dependent changes in mouse skin contracture up to a year after either single dose or fractionated doses of carbon ion or gamma rays

por Ando, Koichi, Yoshida, Yukari, Hirayama, Ryoichi, Koike, Sachiko, Matsufuji, Naruhiro
Publicado 2022

Equivalency of the quality of sublethal lesions after photons and high-linear energy transfer ion beams

por Furusawa, Yoshiya, Nakano-Aoki, Mizuho, Matsumoto, Yoshitaka, Hirayama, Ryoichi, Kobayashi, Alisa, Konishi, Teruaki
Publicado 2017

Fractionated irradiation of carbon beam and the isoeffect dose on acute reaction of skin

por Uzawa, Akiko, Hirayama, Ryoichi, Matsumoto, Yoshitaka, Koda, Kana, Koike, Sachiko, Ando, Koichi, Furusawa, Yoshiya
Publicado 2014

Direct observation of damage clustering in irradiated DNA with atomic force microscopy

por Xu, Xu, Nakano, Toshiaki, Tsuda, Masataka, Kanamoto, Ryota, Hirayama, Ryoichi, Uzawa, Akiko, Ide, Hiroshi
Publicado 2020

Detection of DNA–protein crosslinks (DPCs) by novel direct fluorescence labeling methods: distinct stabilities of aldehyde and radiation-induced DPCs

por Shoulkamy, Mahmoud I., Nakano, Toshiaki, Ohshima, Makiko, Hirayama, Ryoichi, Uzawa, Akiko, Furusawa, Yoshiya, Ide, Hiroshi
Publicado 2012

Hsp90 inhibitor is a good candidate for effective combination therapy with carbon ions

por Okayasu, Ryuichi, Hirakawa, Hirokazu, Masaoka, Aya, Noguchi, Miho, Hirayama, Ryoichi, Li, Huizi, Matsumoto, Yoshitaka, Fujimori, Akira
Publicado 2014

The combination of Hsp90 inhibitor 17AAG and heavy-ion irradiation provides effective tumor control in human lung cancer cells

por Hirakawa, Hirokazu, Fujisawa, Hiroshi, Masaoka, Aya, Noguchi, Miho, Hirayama, Ryoichi, Takahashi, Momoko, Fujimori, Akira, Okayasu, Ryuichi
Publicado 2015

Effect of Gold Nanoparticle Radiosensitization on Plasmid DNA Damage Induced by High-Dose-Rate Brachytherapy

por Yogo, Katsunori, Misawa, Masaki, Shimizu, Morihito, Shimizu, Hidetoshi, Kitagawa, Tomoki, Hirayama, Ryoichi, Ishiyama, Hiromichi, Furukawa, Takako, Yasuda, Hiroshi
Publicado 2021

Radiosensitization Effect of Gold Nanoparticles on Plasmid DNA Damage Induced by Therapeutic MV X-rays

por Yogo, Katsunori, Misawa, Masaki, Shimizu, Hidetoshi, Kitagawa, Tomoki, Hirayama, Ryoichi, Ishiyama, Hiromichi, Yasuda, Hiroshi, Kametaka, Satoshi, Takami, Seiichi
Publicado 2022

Formation of clustered DNA damage in vivo upon irradiation with ionizing radiation: Visualization and analysis with atomic force microscopy

por Nakano, Toshiaki, Akamatsu, Ken, Tsuda, Masataka, Tujimoto, Ayane, Hirayama, Ryoichi, Hiromoto, Takeshi, Tamada, Taro, Ide, Hiroshi, Shikazono, Naoya
Publicado 2022

Kill-painting of hypoxic tumours in charged particle therapy

por Tinganelli, Walter, Durante, Marco, Hirayama, Ryoichi, Krämer, Michael, Maier, Andreas, Kraft-Weyrather, Wilma, Furusawa, Yoshiya, Friedrich, Thomas, Scifoni, Emanuele
Publicado 2015

Carbon ions induce autophagy effectively through stimulating the unfolded protein response and subsequent inhibiting Akt phosphorylation in tumor cells

por Jin, Xiaodong, Li, Feifei, Zheng, Xiaogang, Liu, Yan, Hirayama, Ryoichi, Liu, Xiongxiong, Li, Ping, Zhao, Ting, Dai, Zhongying, Li, Qiang
Publicado 2015

Health effects triggered by tritium: how do we get public understanding based on scientifically supported evidence?

por Matsumoto, Hideki, Shimada, Yoshiya, Nakamura, Asako J, Usami, Noriko, Ojima, Mitsuaki, Kakinuma, Shizuko, Shimada, Mikio, Sunaoshi, Masaaki, Hirayama, Ryoichi, Tauchi, Hiroshi
Publicado 2021

Indirect action to cell killing by SOBP carbon-ion beams

por Hirayama, Ryoichi, Matsumoto, Yoshitaka, Uzawa, Akiko, Kaneko, Yumiko, Koda, Kana, Ozaki, Masakuni, Yamashita, Kei, Li, Huizi, Noguchi, Miho, Shirai, Toshiyuki, Furusawa, Yoshiya
Publicado 2014

Evaluation of X-ray and carbon-ion beam irradiation with chemotherapy for the treatment of cervical adenocarcinoma cells in 2D and 3D cultures

por Sekihara, Kazumasa, Himuro, Hidetomo, Saito, Nao, Ota, Yukihide, Kouro, Taku, Kusano, Yohsuke, Minohara, Shinichi, Hirayama, Ryoichi, Katoh, Hiroyuki, Sasada, Tetsuro, Hoshino, Daisuke
Publicado 2022

Visualisation of γH2AX Foci Caused by Heavy Ion Particle Traversal; Distinction between Core Track versus Non-Track Damage

por Nakajima, Nakako Izumi, Brunton, Holly, Watanabe, Ritsuko, Shrikhande, Amruta, Hirayama, Ryoichi, Matsufuji, Naruhiro, Fujimori, Akira, Murakami, Takeshi, Okayasu, Ryuichi, Jeggo, Penny, Shibata, Atsushi
Publicado 2013

The Effect of p53 Status of Tumor Cells on Radiosensitivity of Irradiated Tumors With Carbon-Ion Beams Compared With γ-Rays or Reactor Neutron Beams

por Masunaga, Shin-ichiro, Uzawa, Akiko, Hirayama, Ryoichi, Matsumoto, Yoshitaka, Sakurai, Yoshinori, Tanaka, Hiroki, Tano, Keizo, Sanada, Yu, Suzuki, Minoru, Maruhashi, Akira, Ono, Koji
Publicado 2015

RBE and OER within the spread-out Bragg peak for proton beam therapy: in vitro study at the Proton Medical Research Center at the University of Tsukuba

por Kanemoto, Ayae, Hirayama, Ryoichi, Moritake, Takashi, Furusawa, Yoshiya, Sun, Lue, Sakae, Takeji, Kuno, Akihiro, Terunuma, Toshiyuki, Yasuoka, Kiyoshi, Mori, Yutaro, Tsuboi, Koji, Sakurai, Hideyuki
Publicado 2014

Comparable radiation sensitivity in p53 wild-type and p53 deficient tumor cells associated with different cell death modalities

por Li, Ping, Liu, Xiongxiong, Zhao, Ting, Li, Feifei, Wang, Qiqi, Zhang, Pengcheng, Hirayama, Ryoichi, Chen, Weiqiang, Jin, Xiaodong, Zheng, Xiaogang, Wang, Zhen, Li, Qiang
Publicado 2021

Performance Evaluation for Repair of HSGc-C5 Carcinoma Cell Using Geant4-DNA

por Sakata, Dousatsu, Suzuki, Masao, Hirayama, Ryoichi, Abe, Yasushi, Muramatsu, Masayuki, Sato, Shinji, Belov, Oleg, Kyriakou, Ioanna, Emfietzoglou, Dimitris, Guatelli, Susanna, Incerti, Sebastien, Inaniwa, Taku
Publicado 2021