Inhibition of adenosine deaminase (ADA)-mediated metabolism of cordycepin by natural substances

por Li, Gen, Nakagome, Izumi, Hirono, Shuichi, Itoh, Tomoo, Fujiwara, Ryoichi
Publicado 2015

Evaluation of Influence of Single Nucleotide Polymorphisms in Cytochrome P450 2B6 on Substrate Recognition Using Computational Docking and Molecular Dynamics Simulation

por Kobayashi, Kana, Takahashi, Ohgi, Hiratsuka, Masahiro, Yamaotsu, Noriyuki, Hirono, Shuichi, Watanabe, Yurie, Oda, Akifumi
Publicado 2014

Design of a New α-1-C-Alkyl-DAB Derivative Acting as a Pharmacological Chaperone for β-Glucocerebrosidase Using Ligand Docking and Molecular Dynamics Simulation

por Nakagome, Izumi, Kato, Atsushi, Yamaotsu, Noriyuki, Yoshida, Tomoki, Ozawa, Shin-ichiro, Adachi, Isao, Hirono, Shuichi
Publicado 2018

Characterizing the selectivity of ER α-glucosidase inhibitors

por O’Keefe, Sarah, Roebuck, Quentin P, Nakagome, Izumi, Hirono, Shuichi, Kato, Atsushi, Nash, Robert, High, Stephen
Publicado 2019

Molecular Dynamics Simulations to Investigate the Influences of Amino Acid Mutations on Protein Three-Dimensional Structures of Cytochrome P450 2D6.1, 2, 10, 14A, 51, and 62

por Fukuyoshi, Shuichi, Kometani, Masaharu, Watanabe, Yurie, Hiratsuka, Masahiro, Yamaotsu, Noriyuki, Hirono, Shuichi, Manabe, Noriyoshi, Takahashi, Ohgi, Oda, Akifumi
Publicado 2016

AMF-26, a Novel Inhibitor of the Golgi System, Targeting ADP-ribosylation Factor 1 (Arf1) with Potential for Cancer Therapy

por Ohashi, Yoshimi, Iijima, Hiroshi, Yamaotsu, Noriyuki, Yamazaki, Kanami, Sato, Shigeo, Okamura, Mutsumi, Sugimoto, Kenji, Dan, Shingo, Hirono, Shuichi, Yamori, Takao
Publicado 2012

Strategy for Designing Selective Lysosomal Acid α-Glucosidase Inhibitors: Binding Orientation and Influence on Selectivity

por Kato, Atsushi, Nakagome, Izumi, Hata, Mizuki, Nash, Robert J., Fleet, George W. J., Natori, Yoshihiro, Yoshimura, Yuichi, Adachi, Isao, Hirono, Shuichi
Publicado 2020

Long chain fatty acids alter the interactive binding of ligands to the two principal drug binding sites of human serum albumin

por Yamasaki, Keishi, Hyodo, Saya, Taguchi, Kazuaki, Nishi, Koji, Yamaotsu, Noriyuki, Hirono, Shuichi, Chuang, Victor Tuan Giam, Seo, Hakaru, Maruyama, Toru, Otagiri, Masaki
Publicado 2017

Differential Effects of Methoxy Group on the Interaction of Curcuminoids with Two Major Ligand Binding Sites of Human Serum Albumin

por Sato, Hiroki, Chuang, Victor Tuan Giam, Yamasaki, Keishi, Yamaotsu, Noriyuki, Watanabe, Hiroshi, Nagumo, Kohei, Anraku, Makoto, Kadowaki, Daisuke, Ishima, Yu, Hirono, Shuichi, Otagiri, Masaki, Maruyama, Toru
Publicado 2014

Efficacy and safety of glecaprevir and pibrentasvir in Japanese patients with hepatitis C virus infection aged 75 years or older

por Komaki, Yuri, Ozono, Yoshinori, Nakamura, Kenichi, Iwakiri, Hisayoshi, Hasuike, Satoru, Sueta, Mitsue, Miike, Tadashi, Yamamoto, Shojiro, Uto, Hirofumi, Kusumoto, Kazunori, Ochiai, Toshimasa, Kato, Junya, Komada, Naoto, Kuroki, Kazuo, Eto, Toshiharu, Shigehira, Masafumi, Hirono, Shuichi, Nagata, Kenji, Kawakami, Hiroshi
Publicado 2022

Efficacy and safety of sofosbuvir and ledipasvir in Japanese patients aged 75 years or over with hepatitis C genotype 1

por Ozono, Yoshinori, Nagata, Kenji, Hasuike, Satoru, Iwakiri, Hisayoshi, Nakamura, Kenichi, Tsuchimochi, Mai, Yamada, Yuri, Takaishi, Yuka, Sueta, Mitsue, Miike, Tadashi, Tahara, Yoshihiro, Yamamoto, Shojiro, Shide, Kotaro, Hidaka, Tomonori, Kubuki, Yoko, Kusumoto, Kazunori, Ochiai, Toshimasa, Kato, Junya, Komada, Naoto, Hirono, Shuichi, Kuroki, Kazuo, Shigehira, Masafumi, Shimoda, Kazuya
Publicado 2017