Synovial Tissue Inflammation Mediated by Autoimmune T Cells

por Takeuchi, Yusuke, Hirota, Keiji, Sakaguchi, Shimon
Publicado 2019

Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

por Veldhoen, Marc, Hirota, Keiji, Christensen, Jillian, O'Garra, Anne, Stockinger, Brigitta
Publicado 2009

Differential Influences of the Aryl Hydrocarbon Receptor on Th17 Mediated Responses in vitro and in vivo

por Duarte, João H., Di Meglio, Paola, Hirota, Keiji, Ahlfors, Helena, Stockinger, Brigitta
Publicado 2013

Uniformity and Efficacy of Dry Powders Delivered to the Lungs of a Mycobacterial-Surrogate Rat Model of Tuberculosis

por Hirota, Keiji, Hirai, Yutaka, Nakajima, Takehisa, Goto, Satoru, Makino, Kimiko, Terada, Hiroshi
Publicado 2021

Foxp3+ Regulatory T Cells Inhibit CCl(4)-Induced Liver Inflammation and Fibrosis by Regulating Tissue Cellular Immunity

por Ikeno, Yoshinobu, Ohara, Daiya, Takeuchi, Yusuke, Watanabe, Hitomi, Kondoh, Gen, Taura, Kojiro, Uemoto, Shinji, Hirota, Keiji
Publicado 2020

T(H)17 cell plasticity in Peyer’s patches is responsible for induction of T cell-dependent IgA responses

por Hirota, Keiji, Turner, Jan-Eric, Villa, Matteo, Duarte, Joao H, Demengeot, Jocelyn, Steinmetz, Oliver M., Stockinger, Brigitta
Publicado 2013

T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17(+) Th cells that cause autoimmune arthritis

por Hirota, Keiji, Hashimoto, Motomu, Yoshitomi, Hiroyuki, Tanaka, Satoshi, Nomura, Takashi, Yamaguchi, Tomoyuki, Iwakura, Yoichiro, Sakaguchi, Noriko, Sakaguchi, Shimon
Publicado 2007

Dispensable roles of Gsdmd and Ripk3 in sustaining IL-1β production and chronic inflammation in Th17-mediated autoimmune arthritis

por Takeuchi, Yusuke, Ohara, Daiya, Watanabe, Hitomi, Sakaguchi, Noriko, Sakaguchi, Shimon, Kondoh, Gen, Morinobu, Akio, Mimori, Tsuneyo, Hirota, Keiji
Publicado 2021

Interleukin 9 fate reporter reveals induction of innate IL-9 response in lung inflammation

por Wilhelm, Christoph, Hirota, Keiji, Stieglitz, Benjamin, Van Snick, Jacques, Tolaini, Mauro, Lahl, Katharina, Sparwasser, Tim, Helmby, Helena, Stockinger, Brigitta
Publicado 2011

Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation

por Yasuda, Keiko, Kitagawa, Yohko, Kawakami, Ryoji, Isaka, Yoshitaka, Watanabe, Hitomi, Kondoh, Gen, Kohwi-Shigematsu, Terumi, Sakaguchi, Shimon, Hirota, Keiji
Publicado 2019

Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3(+)CD25(+)CD4(+) regulatory T cells

por Ko, Kuibeom, Yamazaki, Sayuri, Nakamura, Kyoko, Nishioka, Tomohisa, Hirota, Keiji, Yamaguchi, Tomoyuki, Shimizu, Jun, Nomura, Takashi, Chiba, Tsutomu, Sakaguchi, Shimon
Publicado 2005

Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3(+)CD25(+)CD4(+) regulatory T cells

por Ko, Kuibeom, Yamazaki, Sayuri, Nakamura, Kyoko, Nishioka, Tomohisa, Hirota, Keiji, Yamaguchi, Tomoyuki, Shimizu, Jun, Nomura, Takashi, Chiba, Tsutomu, Sakaguchi, Shimon
Publicado 2012

Identification of a genomic enhancer that enforces proper apoptosis induction in thymic negative selection

por Hojo, Miki Arai, Masuda, Kyoko, Hojo, Hiroaki, Nagahata, Yosuke, Yasuda, Keiko, Ohara, Daiya, Takeuchi, Yusuke, Hirota, Keiji, Suzuki, Yutaka, Kawamoto, Hiroshi, Kawaoka, Shinpei
Publicado 2019

Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model

por Hirota, Keiji, Yoshitomi, Hiroyuki, Hashimoto, Motomu, Maeda, Shinji, Teradaira, Shin, Sugimoto, Naoshi, Yamaguchi, Tomoyuki, Nomura, Takashi, Ito, Hiromu, Nakamura, Takashi, Sakaguchi, Noriko, Sakaguchi, Shimon
Publicado 2007

Clinical and Histopathological Amelioration of Experimental Autoimmune Encephalomyelitis by AAV Vectors Expressing a Soluble Interleukin-23 Receptor

por Miralles, Marta, Eixarch, Herena, Tejero, Marcos, Costa, Carme, Hirota, Keiji, Castaño, A. Raul, Puig, Meritxell, Stockinger, Gitta, Montalban, Xavier, Bosch, Assumpció, Espejo, Carmen, Chillon, Miguel
Publicado 2017

A role for fungal β-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice

por Yoshitomi, Hiroyuki, Sakaguchi, Noriko, Kobayashi, Katsuya, Brown, Gordon D., Tagami, Tomoyuki, Sakihama, Toshiko, Hirota, Keiji, Tanaka, Satoshi, Nomura, Takashi, Miki, Ichiro, Gordon, Siamon, Akira, Shizuo, Nakamura, Takashi, Sakaguchi, Shimon
Publicado 2005

Activation of the Aryl Hydrocarbon Receptor Dampens the Severity of Inflammatory Skin Conditions

por Di Meglio, Paola, Duarte, João H., Ahlfors, Helena, Owens, Nick D.L., Li, Ying, Villanova, Federica, Tosi, Isabella, Hirota, Keiji, Nestle, Frank O., Mrowietz, Ulrich, Gilchrist, Michael J., Stockinger, Brigitta
Publicado 2014

Complement drives Th17 cell differentiation and triggers autoimmune arthritis

por Hashimoto, Motomu, Hirota, Keiji, Yoshitomi, Hiroyuki, Maeda, Shinji, Teradaira, Shin, Akizuki, Shuji, Prieto-Martin, Paz, Nomura, Takashi, Sakaguchi, Noriko, Köhl, Jörg, Heyman, Birgitta, Takahashi, Minoru, Fujita, Teizo, Mimori, Tsuneyo, Sakaguchi, Shimon
Publicado 2010

Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis

por Hirota, Keiji, Hashimoto, Motomu, Ito, Yoshinaga, Matsuura, Mayumi, Ito, Hiromu, Tanaka, Masao, Watanabe, Hitomi, Kondoh, Gen, Tanaka, Atsushi, Yasuda, Keiko, Kopf, Manfred, Potocnik, Alexandre J., Stockinger, Brigitta, Sakaguchi, Noriko, Sakaguchi, Shimon
Publicado 2018

Construction of a T cell receptor signaling range for spontaneous development of autoimmune disease

por Tanaka, Atsushi, Maeda, Shinji, Nomura, Takashi, Llamas-Covarrubias, Mara Anais, Tanaka, Satoshi, Jin, Lin, Lim, Ee Lyn, Morikawa, Hiromasa, Kitagawa, Yohko, Akizuki, Shuji, Ito, Yoshinaga, Fujimori, Chihiro, Hirota, Keiji, Murase, Tosei, Hashimoto, Motomu, Higo, Junichi, Zamoyska, Rose, Ueda, Ryuzo, Standley, Daron M., Sakaguchi, Noriko, Sakaguchi, Shimon
Publicado 2022