Blockade of miR-140-3p prevents functional deterioration in afterload-enhanced engineered heart tissue

por Werner, Tessa R., Kunze, Ann-Cathrin, Stenzig, Justus, Eschenhagen, Thomas, Hirt, Marc N.
Publicado 2019

Identification of hypertrophy-modulating Cullin-RING ubiquitin ligases in primary cardiomyocytes

por Fischer, Maximillian, Jakab, Moritz, Hirt, Marc N., Werner, Tessa R., Engelhardt, Stefan, Sarikas, Antonio
Publicado 2023

Effects of the Delta Opioid Receptor Agonist DADLE in a Novel Hypoxia-Reoxygenation Model on Human and Rat-Engineered Heart Tissue: A Pilot Study

por Funcke, Sandra, Werner, Tessa R., Hein, Marc, Ulmer, Bärbel M., Hansen, Arne, Eschenhagen, Thomas, Hirt, Marc N.
Publicado 2020

Recapitulation of dyssynchrony-associated contractile impairment in asymmetrically paced engineered heart tissue

por Stenzig, Justus, Lemoine, Marc D., Stoter, Aaltje M.S., Wrona, Kinga M., Lemme, Marta, Mulla, Wesam, Etzion, Yoram, Eschenhagen, Thomas, Hirt, Marc N.
Publicado 2022

S100A4 as a Target of the E3-Ligase Asb2β and Its Effect on Engineered Heart Tissue

por Braumann, Simon, Thottakara, Tilo, Stücker, Sabrina, Reischmann-Düsener, Silke, Krämer, Elisabeth, Groß, Julia, Hirt, Marc N., Doroudgar, Shirin, Carrier, Lucie, Friedrich, Felix W.
Publicado 2018

Piezo2 is not an indispensable mechanosensor in murine cardiomyocytes

por Kloth, Benjamin, Mearini, Giulia, Weinberger, Florian, Stenzig, Justus, Geertz, Birgit, Starbatty, Jutta, Lindner, Diana, Schumacher, Udo, Reichenspurner, Hermann, Eschenhagen, Thomas, Hirt, Marc N.
Publicado 2022

Human Engineered Heart Tissue as a Versatile Tool in Basic Research and Preclinical Toxicology

por Schaaf, Sebastian, Shibamiya, Aya, Mewe, Marco, Eder, Alexandra, Stöhr, Andrea, Hirt, Marc N., Rau, Thomas, Zimmermann, Wolfram-Hubertus, Conradi, Lenard, Eschenhagen, Thomas, Hansen, Arne
Publicado 2011

Increased afterload induces pathological cardiac hypertrophy: a new in vitro model

por Hirt, Marc N., Sörensen, Nils A., Bartholdt, Lena M., Boeddinghaus, Jasper, Schaaf, Sebastian, Eder, Alexandra, Vollert, Ingra, Stöhr, Andrea, Schulze, Thomas, Witten, Anika, Stoll, Monika, Hansen, Arne, Eschenhagen, Thomas
Publicado 2012

Analysis of Tyrosine Kinase Inhibitor-Mediated Decline in Contractile Force in Rat Engineered Heart Tissue

por Jacob, Fabian, Yonis, Amina Y., Cuello, Friederike, Luther, Pradeep, Schulze, Thomas, Eder, Alexandra, Streichert, Thomas, Mannhardt, Ingra, Hirt, Marc N., Schaaf, Sebastian, Stenzig, Justus, Force, Thomas, Eschenhagen, Thomas, Hansen, Arne
Publicado 2016

Correction: Analysis of Tyrosine Kinase Inhibitor-Mediated Decline in Contractile Force in Rat Engineered Heart Tissue

por Jacob, Fabian, Yonis, Amina Y., Cuello, Friederike, Luther, Pradeep, Schulze, Thomas, Eder, Alexandra, Streichert, Thomas, Mannhardt, Ingra, Hirt, Marc N., Schaaf, Sebastian, Stenzig, Justus, Force, Thomas, Eschenhagen, Thomas, Hansen, Arne
Publicado 2018

Phosphomimetic cardiac myosin-binding protein C partially rescues a cardiomyopathy phenotype in murine engineered heart tissue

por Dutsch, Alexander, Wijnker, Paul J. M., Schlossarek, Saskia, Friedrich, Felix W., Krämer, Elisabeth, Braren, Ingke, Hirt, Marc N., Brenière-Letuffe, David, Rhoden, Alexandra, Mannhardt, Ingra, Eschenhagen, Thomas, Carrier, Lucie, Mearini, Giulia
Publicado 2019

Human iPSC-derived cardiomyocytes cultured in 3D engineered heart tissue show physiological upstroke velocity and sodium current density

por Lemoine, Marc D., Mannhardt, Ingra, Breckwoldt, Kaja, Prondzynski, Maksymilian, Flenner, Frederik, Ulmer, Bärbel, Hirt, Marc N., Neuber, Christiane, Horváth, András, Kloth, Benjamin, Reichenspurner, Hermann, Willems, Stephan, Hansen, Arne, Eschenhagen, Thomas, Christ, Torsten
Publicado 2017

Human Engineered Heart Tissue: Analysis of Contractile Force

por Mannhardt, Ingra, Breckwoldt, Kaja, Letuffe-Brenière, David, Schaaf, Sebastian, Schulz, Herbert, Neuber, Christiane, Benzin, Anika, Werner, Tessa, Eder, Alexandra, Schulze, Thomas, Klampe, Birgit, Christ, Torsten, Hirt, Marc N., Huebner, Norbert, Moretti, Alessandra, Eschenhagen, Thomas, Hansen, Arne
Publicado 2016

An Important Role for DNMT3A-Mediated DNA Methylation in Cardiomyocyte Metabolism and Contractility

por Madsen, Alexandra, Höppner, Grit, Krause, Julia, Hirt, Marc N., Laufer, Sandra D., Schweizer, Michaela, Tan, Wilson Lek Wen, Mosqueira, Diogo, Anene-Nzelu, Chukwuemeka George, Lim, Ives, Foo, Roger S.Y., Hansen, Arne, Eschenhagen, Thomas, Stenzig, Justus
Publicado 2020

Long Noncoding RNA-Enriched Vesicles Secreted by Hypoxic Cardiomyocytes Drive Cardiac Fibrosis

por Kenneweg, Franziska, Bang, Claudia, Xiao, Ke, Boulanger, Chantal M., Loyer, Xavier, Mazlan, Stephane, Schroen, Blanche, Hermans-Beijnsberger, Steffie, Foinquinos, Ariana, Hirt, Marc N., Eschenhagen, Thomas, Funcke, Sandra, Stojanovic, Stevan, Genschel, Celina, Schimmel, Katharina, Just, Annette, Pfanne, Angelika, Scherf, Kristian, Dehmel, Susann, Raemon-Buettner, Stella M., Fiedler, Jan, Thum, Thomas
Publicado 2019

Targeting muscle-enriched long non-coding RNA H19 reverses pathological cardiac hypertrophy

por Viereck, Janika, Bührke, Anne, Foinquinos, Ariana, Chatterjee, Shambhabi, Kleeberger, Jan A, Xiao, Ke, Janssen-Peters, Heike, Batkai, Sandor, Ramanujam, Deepak, Kraft, Theresia, Cebotari, Serghei, Gueler, Faikah, Beyer, Andreas M, Schmitz, Jessica, Bräsen, Jan H, Schmitto, Jan D, Gyöngyösi, Mariann, Löser, Alexandra, Hirt, Marc N, Eschenhagen, Thomas, Engelhardt, Stefan, Bär, Christian, Thum, Thomas
Publicado 2020

Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia

por Schäfer, Michaela, Oeing, Christian U., Rohm, Maria, Baysal-Temel, Ezgi, Lehmann, Lorenz H., Bauer, Ralf, Volz, H. Christian, Boutros, Michael, Sohn, Daniela, Sticht, Carsten, Gretz, Norbert, Eichelbaum, Katrin, Werner, Tessa, Hirt, Marc N., Eschenhagen, Thomas, Müller-Decker, Karin, Strobel, Oliver, Hackert, Thilo, Krijgsveld, Jeroen, Katus, Hugo A., Berriel Diaz, Mauricio, Backs, Johannes, Herzig, Stephan
Publicado 2015

‘Corrigendum to “Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia” [Molecular Metabolism 5 (2) (2015) 67–78]’

por Schäfer, Michaela, Oeing, Christian U., Rohm, Maria, Baysal-Temel, Ezgi, Lehmann, Lorenz H., Bauer, Ralf, Volz, H. Christian, Boutros, Michael, Sohn, Daniela, Sticht, Carsten, Gretz, Norbert, Eichelbaum, Katrin, Werner, Tessa, Hirt, Marc N., Eschenhagen, Thomas, Müller-Decker, Karin, Strobel, Oliver, Hackert, Thilo, Krijgsveld, Jeroen, Katus, Hugo A., Berriel Diaz, Mauricio, Backs, Johannes, Herzig, Stephan
Publicado 2020

Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction

por Trembinski, D. Julia, Bink, Diewertje I., Theodorou, Kosta, Sommer, Janina, Fischer, Ariane, van Bergen, Anke, Kuo, Chao-Chung, Costa, Ivan G., Schürmann, Christoph, Leisegang, Matthias S., Brandes, Ralf P., Alekseeva, Tijna, Brill, Boris, Wietelmann, Astrid, Johnson, Christopher N., Spring-Connell, Alexander, Kaulich, Manuel, Werfel, Stanislas, Engelhardt, Stefan, Hirt, Marc N., Yorgan, Kaja, Eschenhagen, Thomas, Kirchhof, Luisa, Hofmann, Patrick, Jaé, Nicolas, Wittig, Ilka, Hamdani, Nazha, Bischof, Corinne, Krishnan, Jaya, Houtkooper, Riekelt H., Dimmeler, Stefanie, Boon, Reinier A.
Publicado 2020