Direct evidence that the GPCR CysLTR2 mutant causative of uveal melanoma is constitutively active with highly biased signaling

por Ceraudo, Emilie, Horioka, Mizuho, Mattheisen, Jordan M., Hitchman, Tyler D., Moore, Amanda R., Kazmi, Manija A., Chi, Ping, Chen, Yu, Sakmar, Thomas P., Huber, Thomas
Publicado 2020

GNA11 Q209L Mouse Model Reveals RasGRP3 as an Essential Signaling Node in Uveal Melanoma

por Moore, Amanda R., Ran, Leili, Guan, Youxin, Sher, Jessica J., Hitchman, Tyler D., Zhang, Jenny Q., Hwang, Catalina, Walzak, Edward G., Shoushtari, Alexander N., Monette, Sébastien, Murali, Rajmohan, Wiesner, Thomas, Griewank, Klaus G., Chi, Ping, Chen, Yu
Publicado 2018

GNA11 Q209L Mouse Model Reveals RasGRP3 as an Essential Signaling Node in Uveal Melanoma

por Moore, Amanda R., Ran, Leili, Guan, Youxin, Sher, Jessica J., Hitchman, Tyler D., Zhang, Jenny Q., Hwang, Catalina, Walczak, Edward G., Shoushtari, Alexander N., Monette, Sébastien, Murali, Rajmohan, Wiesner, Thomas, Griewank, Klaus G., Chi, Ping, Chen, Yu
Publicado 2020

Spliceosomal disruption of the non-canonical BAF complex in cancer

por Inoue, Daichi, Chew, Guo-Liang, Liu, Bo, Michel, Brittany C., Pangallo, Joseph, D’Avino, Andrew R., Hitchman, Tyler, North, Khrystyna, Lee, Stanley Chun-Wei, Bitner, Lillian, Block, Ariele, Moore, Amanda R., Yoshimi, Akihide, Escobar-Hoyos, Luisa, Cho, Hana, Penson, Alex, Lu, Sydney X., Taylor, Justin, Chen, Yu, Kadoch, Cigall, Abdel-Wahab, Omar, Bradley, Robert K.
Publicado 2019