Sequence Versus Composition: What Prescribes IDP Biophysical Properties?

por Vymětal, Jiří, Vondrášek, Jiří, Hlouchová, Klára
Publicado 2019

CoLiDe: Combinatorial Library Design tool for probing protein sequence space

por Tretyachenko, Vyacheslav, Voráček, Václav, Souček, Radko, Fujishima, Kosuke, Hlouchová, Klára
Publicado 2020

Peptides before and during the nucleotide world: an origins story emphasizing cooperation between proteins and nucleic acids

por Fried, Stephen D., Fujishima, Kosuke, Makarov, Mikhail, Cherepashuk, Ivan, Hlouchova, Klara
Publicado 2022

Modern and prebiotic amino acids support distinct structural profiles in proteins

por Tretyachenko, Vyacheslav, Vymětal, Jiří, Neuwirthová, Tereza, Vondrášek, Jiří, Fujishima, Kosuke, Hlouchová, Klára
Publicado 2022

Experimental characterization of de novo proteins and their unevolved random-sequence counterparts

por Heames, Brennen, Buchel, Filip, Aubel, Margaux, Tretyachenko, Vyacheslav, Loginov, Dmitry, Novák, Petr, Lange, Andreas, Bornberg-Bauer, Erich, Hlouchová, Klára
Publicado 2023

In Vitro Evolution Reveals Noncationic Protein–RNA Interaction Mediated by Metal Ions

por Giacobelli, Valerio G, Fujishima, Kosuke, Lepšík, Martin, Tretyachenko, Vyacheslav, Kadavá, Tereza, Makarov, Mikhail, Bednárová, Lucie, Novák, Petr, Hlouchová, Klára
Publicado 2022

Random protein sequences can form defined secondary structures and are well-tolerated in vivo

por Tretyachenko, Vyacheslav, Vymětal, Jiří, Bednárová, Lucie, Kopecký, Vladimír, Hofbauerová, Kateřina, Jindrová, Helena, Hubálek, Martin, Souček, Radko, Konvalinka, Jan, Vondrášek, Jiří, Hlouchová, Klára
Publicado 2017

Early Selection of the Amino Acid Alphabet Was Adaptively Shaped by Biophysical Constraints of Foldability

por Makarov, Mikhail, Sanchez Rocha, Alma C., Krystufek, Robin, Cherepashuk, Ivan, Dzmitruk, Volha, Charnavets, Tatsiana, Faustino, Anneliese M., Lebl, Michal, Fujishima, Kosuke, Fried, Stephen D., Hlouchova, Klara
Publicado 2023