G2019s LRRK2 promotes mitochondrial fission and increases TNFα-mediated neuroinflammation responses

por Ho, Dong Hwan, Lee, Heajin, Son, Ilhong, Seol, Wongi
Publicado 2019

Increased DJ-1 in Urine Exosome of Korean Males with Parkinson's Disease

por Ho, Dong Hwan, Yi, Sanghak, Seo, Hyemyung, Son, Ilhong, Seol, Wongi
Publicado 2014

Nuclear α-Synuclein-Derived Cytotoxic Effect via Altered Ribosomal RNA Processing in Primary Mouse Embryonic Fibroblasts

por Ho, Dong Hwan, Kim, Hyejung, Nam, Daleum, Heo, Jinju, Son, Ilhong
Publicado 2023

G2385R and I2020T Mutations Increase LRRK2 GTPase Activity

por Ho, Dong Hwan, Jang, Jihoon, Joe, Eun-hye, Son, Ilhong, Seo, Hyemyung, Seol, Wongi
Publicado 2016

LRRK2 Inhibition Mitigates the Neuroinflammation Caused by TLR2-Specific α-Synuclein and Alleviates Neuroinflammation-Derived Dopaminergic Neuronal Loss

por Ho, Dong-Hwan, Nam, Daleum, Seo, Mikyoung, Park, Sung-Woo, Seol, Wongi, Son, Ilhong
Publicado 2022

LRRK2 Kinase Inhibitor Rejuvenates Oxidative Stress-Induced Cellular Senescence in Neuronal Cells

por Ho, Dong Hwan, Nam, Daleum, Seo, Mi Kyoung, Park, Sung Woo, Seol, Wongi, Son, Ilhong
Publicado 2021

Oxidized DJ-1 Levels in Urine Samples as a Putative Biomarker for Parkinson's Disease

por Jang, Jihoon, Jeong, Soyeon, Lee, Sung Ik, Seol, Wongi, Seo, Hyemyung, Son, Ilhong, Ho, Dong Hwan
Publicado 2018

LRRK2 Kinase Activity Induces Mitochondrial Fission in Microglia via Drp1 and Modulates Neuroinflammation

por Ho, Dong Hwan, Je, A Reum, Lee, Haejin, Son, Ilhong, Kweon, Hee-Seok, Kim, Hyung-Gun, Seol, Wongi
Publicado 2018

Analysis of α-synuclein levels related to LRRK2 kinase activity: from substantia nigra to urine of patients with Parkinson’s disease

por Nam, Daleum, Kim, Ami, Han, Sun Jung, Lee, Sung-Ik, Park, Sung-Hye, Seol, Wongi, Son, Ilhong, Ho, Dong Hwan
Publicado 2021

Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity

por Jang, Jihoon, Oh, Hakjin, Nam, Daleum, Seol, Wongi, Seo, Mi Kyoung, Park, Sung Woo, Kim, Hyung Gun, Seo, Hyemyung, Son, Ilhong, Ho, Dong Hwan
Publicado 2018

LRRK2 phosphorylates Snapin and inhibits interaction of Snapin with SNAP-25

por Yun, Hye Jin, Park, Joohyun, Ho, Dong Hwan, Kim, Heyjung, Kim, Cy-Hyun, Oh, Hakjin, Ga, Inhwa, Seo, Hyemyung, Chang, Sunghoe, Son, Ilhong, Seol, Wongi
Publicado 2013

Dexamethasone induces the expression of LRRK2 and α-synuclein, two genes that when mutated cause Parkinson’s disease in an autosomal dominant manner

por Park, Ji-Min, Ho, Dong-Hwan, Yun, Hye Jin, Kim, Hye-Jung, Lee, Chan Hong, Park, Sung Woo, Kim, Young Hoon, Son, Ilhong, Seol, Wongi
Publicado 2013

Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21(WAF1/CIP1) expression

por Ho, Dong Hwan, Kim, Hyejung, Kim, Jisun, Sim, Hyuna, Ahn, Hyunjun, Kim, Janghwan, Seo, Hyemyung, Chung, Kwang Chul, Park, Bum-Joon, Son, Ilhong, Seol, Wongi
Publicado 2015

Correction to: Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21(WAF1/CIP1) expression

por Ho, Dong Hwan, Kim, Hyejung, Kim, Jisun, Sim, Hyuna, Ahn, Hyunjun, Kim, Janghwan, Seo, Hyemyung, Chung, Kwang Chul, Park, Bum-Joon, Son, Ilhong, Seol, Wongi
Publicado 2017