PMCA4 (ATP2B4) Mutation in Familial Spastic Paraplegia

por Li, Miaoxin, Ho, Philip Wing-Lok, Pang, Shirley Yin-Yu, Tse, Zero Ho-Man, Kung, Michelle Hiu-Wai, Sham, Pak-Chung, Ho, Shu-Leong
Publicado 2014

PMCA4 (ATP2B4) mutation in familial spastic paraplegia causes delay in intracellular calcium extrusion

por Ho, Philip Wing-Lok, Pang, Shirley Yin-Yu, Li, Miaoxin, Tse, Zero Ho-Man, Kung, Michelle Hiu-Wai, Sham, Pak-Chung, Ho, Shu-Leong
Publicado 2015

The interplay of aging, genetics and environmental factors in the pathogenesis of Parkinson’s disease

por Pang, Shirley Yin-Yu, Ho, Philip Wing-Lok, Liu, Hui-Fang, Leung, Chi-Ting, Li, Lingfei, Chang, Eunice Eun Seo, Ramsden, David Boyer, Ho, Shu-Leong
Publicado 2019

Assessment of Cellular Estrogenic Activity Based on Estrogen Receptor-Mediated Reduction of Soluble-Form Catechol-O-Methyltransferase (COMT) Expression in an ELISA-Based System

por Ho, Philip Wing-Lok, Tse, Zero Ho-Man, Liu, Hui-Fang, Lu, Song, Ho, Jessica Wing-Man, Kung, Michelle Hiu-Wai, Ramsden, David Boyer, Ho, Shu-Leong
Publicado 2013

Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors

por Ito, Genta, Katsemonova, Kristina, Tonelli, Francesca, Lis, Pawel, Baptista, Marco A.S., Shpiro, Natalia, Duddy, Graham, Wilson, Steve, Ho, Philip Wing-Lok, Ho, Shu-Leong, Reith, Alastair D., Alessi, Dario R.
Publicado 2016

LRRK2 mutant knock-in mouse models: therapeutic relevance in Parkinson's disease

por Chang, Eunice Eun Seo, Ho, Philip Wing-Lok, Liu, Hui-Fang, Pang, Shirley Yin-Yu, Leung, Chi-Ting, Malki, Yasine, Choi, Zoe Yuen-Kiu, Ramsden, David Boyer, Ho, Shu-Leong
Publicado 2022

Combined LRRK2 mutation, aging and chronic low dose oral rotenone as a model of Parkinson’s disease

por Liu, Hui-Fang, Ho, Philip Wing-Lok, Leung, Gideon Chi-Ting, Lam, Colin Siu-Chi, Pang, Shirley Yin-Yu, Li, Lingfei, Kung, Michelle Hiu-Wai, Ramsden, David Boyer, Ho, Shu-Leong
Publicado 2017

Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of cha...

por Ho, Philip Wing-Lok, Leung, Chi-Ting, Liu, Huifang, Pang, Shirley Yin-Yu, Lam, Colin Siu-Chi, Xian, Jiawen, Li, Lingfei, Kung, Michelle Hiu-Wai, Ramsden, David Boyer, Ho, Shu-Leong
Publicado 2019

Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2(R1441G) mice

por Liu, Huifang, Ho, Philip Wing-Lok, Leung, Chi-Ting, Pang, Shirley Yin-Yu, Chang, Eunice Eun Seo, Choi, Zoe Yuen-Kiu, Kung, Michelle Hiu-Wai, Ramsden, David Boyer, Ho, Shu-Leong
Publicado 2020

Transcriptional Regulation of the Synaptic Vesicle Protein Synaptogyrin-3 (SYNGR3) Gene: The Effects of NURR1 on Its Expression

por Li, Lingfei, Ho, Philip Wing-Lok, Liu, Huifang, Pang, Shirley Yin-Yu, Chang, Eunice Eun-Seo, Choi, Zoe Yuen-Kiu, Malki, Yasine, Kung, Michelle Hiu-Wai, Ramsden, David Boyer, Ho, Shu-Leong
Publicado 2022

Mitochondrial Uncoupling Protein-2 (UCP2) Mediates Leptin Protection Against MPP(+) Toxicity in Neuronal Cells

por Ho, Philip Wing-Lok, Liu, Hui-Fang, Ho, Jessica Wing-Man, Zhang, Wei-Yi, Chu, Andrew Chi-Yuen, Kwok, Ken Hon-Hung, Ge, Xuan, Chan, Koon-Ho, Ramsden, David Boyer, Ho, Shu-Leong
Publicado 2009

Adiponectin is Protective against Oxidative Stress Induced Cytotoxicity in Amyloid-Beta Neurotoxicity

por Chan, Koon-Ho, Lam, Karen Siu-Ling, Cheng, On-Yin, Kwan, Jason Shing-Cheong, Ho, Philip Wing-Lok, Cheng, Kenneth King-Yip, Chung, Sookja Kim, Ho, Jessica Wing-Man, Guo, Vivian Yawei, Xu, Almin
Publicado 2012

LRRK2 R1441G mice are more liable to dopamine depletion and locomotor inactivity

por Liu, Hui-Fang, Lu, Song, Ho, Philip Wing-Lok, Tse, Ho-Man, Pang, Shirley Yin-Yu, Kung, Michelle Hiu-Wai, Ho, Jessica Wing-Man, Ramsden, David B, Zhou, Zhong-Jun, Ho, Shu-Leong
Publicado 2014

A randomized controlled trial on the effects and acceptability of individual mindfulness techniques – meditation and yoga – on anxiety and depression in people with Parkinson’s dis...

por Kwok, Jojo Yan Yan, Auyeung, Man, Pang, Shirley Yin Yu, Ho, Philip Wing Lok, Yu, Doris Sau Fung, Fong, Daniel Yee Tak, Lin, Chia-chin, Walker, Richard, Wong, Samuel Yeung-shan, Ho, Rainbow Tin Hung
Publicado 2023

Uncoupling Protein-4 (UCP4) Increases ATP Supply by Interacting with Mitochondrial Complex II in Neuroblastoma Cells

por Ho, Philip Wing-Lok, Ho, Jessica Wing-Man, Tse, Ho-Man, So, Danny Hon-Fai, Yiu, David Chi-Wai, Liu, Hui-Fang, Chan, Koon-Ho, Kung, Michelle Hiu-Wai, Ramsden, David Boyer, Ho, Shu-Leong
Publicado 2012

In vivo overexpression of synaptogyrin‐3 promotes striatal synaptic dopamine uptake in LRRK2(R1441G) mutant mouse model of Parkinson's disease

por Ho, Philip Wing‐Lok, Li, Lingfei, Liu, Hui‐Fang, Choi, Zoe Yuen‐Kiu, Chang, Eunice Eun Seo, Pang, Shirley Yin‐Yu, Malki, Yasine, Leung, Chi‐Ting, Kung, Michelle Hiu‐Wai, Ramsden, David Boyer, Ho, Shu‐Leong
Publicado 2023

Deficiency of Cks1 Leads to Learning and Long-Term Memory Defects and p27 Dependent Formation of Neuronal Cofilin Aggregates

por Kukalev, Alexander, Ng, Yiu-Ming, Ju, Limei, Saidi, Amal, Lane, Sophie, Mondragon, Angeles, Dormann, Dirk, Walker, Sophie E., Grey, William, Ho, Philip Wing-Lok, Stephens, David N., Carr, Antony M., Lamsa, Karri, Tse, Eric, Yu, Veronica P. C. C.
Publicado 2017

LRRK2, GBA and their interaction in the regulation of autophagy: implications on therapeutics in Parkinson's disease

por Pang, Shirley Yin-Yu, Lo, Rachel Cheuk Nam, Ho, Philip Wing-Lok, Liu, Hui-Fang, Chang, Eunice Eun Seo, Leung, Chi-Ting, Malki, Yasine, Choi, Zoe Yuen-Kiu, Wong, Wing Yan, Kung, Michelle Hiu-Wai, Ramsden, David Boyer, Ho, Shu-Leong
Publicado 2022

Chronic adiponectin deficiency leads to Alzheimer’s disease-like cognitive impairments and pathologies through AMPK inactivation and cerebral insulin resistance in aged mice

por Ng, Roy Chun-Laam, Cheng, On-Yin, Jian, Min, Kwan, Jason Shing-Cheong, Ho, Philip Wing-Lok, Cheng, Kenneth King-Yip, Yeung, Patrick Ka Kit, Zhou, Lena Lei, Hoo, Ruby Lai-Chong, Chung, Sookja Kim, Xu, Aimin, Lam, Karen Siu-Ling., Chan, Koon Ho
Publicado 2016

Long-term inhibition of mutant LRRK2 hyper-kinase activity reduced mouse brain α-synuclein oligomers without adverse effects

por Ho, Philip Wing-Lok, Chang, Eunice Eun-Seo, Leung, Chi-Ting, Liu, Huifang, Malki, Yasine, Pang, Shirley Yin-Yu, Choi, Zoe Yuen-Kiu, Liang, Yingmin, Lai, Weng Seng, Ruan, Yuefei, Leung, Kenneth Mei-Yee, Yung, Susan, Mak, Judith Choi-Wo, Kung, Michelle Hiu-Wai, Ramsden, David B., Ho, Shu-Leong
Publicado 2022