Arsenic Trioxide and Venetoclax Synergize against AML Progenitors by ROS Induction and Inhibition of Nrf2 Activation

por Hoang, Dinh Hoa, Buettner, Ralf, Valerio, Melissa, Ghoda, Lucy, Zhang, Bin, Kuo, Ya-Huei, Rosen, Steven T., Burnett, John, Marcucci, Guido, Pullarkat, Vinod, Nguyen, Le Xuan Truong
Publicado 2022

MicroRNA networks in FLT3-ITD acute myeloid leukemia

por Hoang, Dinh Hoa, Zhao, Dandan, Branciamore, Sergio, Maestrini, Davide, Rodriguez, Ivan R., Kuo, Ya-Huei, Rockne, Russell, Khaled, Samer K., Zhang, Bin, Nguyen, Le Xuan Truong, Marcucci, Guido
Publicado 2022

Targeting the metabolic vulnerability of acute myeloid leukemia blasts with a combination of venetoclax and 8-chloro-adenosine

por Buettner, Ralf, Nguyen, Le Xuan Truong, Morales, Corey, Chen, Min-Hsuan, Wu, Xiwei, Chen, Lisa S., Hoang, Dinh Hoa, Hernandez Vargas, Servando, Pullarkat, Vinod, Gandhi, Varsha, Marcucci, Guido, Rosen, Steven T.
Publicado 2021

Synergy of Venetoclax and 8-Chloro-Adenosine in AML: The Interplay of rRNA Inhibition and Fatty Acid Metabolism

por Hoang, Dinh Hoa, Morales, Corey, Rodriguez, Ivan Rodriguez, Valerio, Melissa, Guo, Jiamin, Chen, Min-Hsuan, Wu, Xiwei, Horne, David, Gandhi, Varsha, Chen, Lisa S., Zhang, Bin, Pullarkat, Vinod, Rosen, Steven T., Marcucci, Guido, Buettner, Ralf, Nguyen, Le Xuan Truong
Publicado 2022

Cytoplasmic DROSHA and Non-canonical Mechanisms of MiR-155 Biogenesis in FLT3-ITD Acute Myeloid Leukemia

por Nguyen, Le Xuan Truong, Zhang, Bin, Hoang, Dinh Hoa, Zhao, Dandan, Wang, Huafeng, Wu, Herman, Su, Yu-Lin, Dong, Haojie, Rodriguez-Rodriguez, Sonia, Armstrong, Brian, Ghoda, Lucy Y., Perrotti, Danilo, Pichiorri, Flavia, Chen, Jianjun, Li, Ling, Kortylewski, Marcin, Rockne, Russell C., Kuo, Ya-Huei, Khaled, Samer, Carlesso, Nadia, Marcucci, Guido
Publicado 2021

Targeting miR-126 in inv(16) acute myeloid leukemia inhibits leukemia development and leukemia stem cell maintenance

por Zhang, Lianjun, Nguyen, Le Xuan Truong, Chen, Ying-Chieh, Wu, Dijiong, Cook, Guerry J., Hoang, Dinh Hoa, Brewer, Casey J., He, Xin, Dong, Haojie, Li, Shu, Li, Man, Zhao, Dandan, Qi, Jing, Hua, Wei-Kai, Cai, Qi, Carnahan, Emily, Chen, Wei, Wu, Xiwei, Swiderski, Piotr, Rockne, Russell C., Kortylewski, Marcin, Li, Ling, Zhang, Bin, Marcucci, Guido, Kuo, Ya-Huei
Publicado 2021

Treatment-induced arteriolar revascularization and miR-126 enhancement in bone marrow niche protect leukemic stem cells in AML

por Zhang, Bin, Nguyen, Le Xuan Truong, Zhao, Dandan, Frankhouser, David E., Wang, Huafeng, Hoang, Dinh Hoa, Qiao, Junjing, Abundis, Christina, Brehove, Matthew, Su, Yu-Lin, Feng, Yuxin, Stein, Anthony, Ghoda, Lucy, Dorrance, Adrianne, Perrotti, Danilo, Chen, Zhen, Han, Anjia, Pichiorri, Flavia, Jin, Jie, Jovanovic-Talisman, Tijana, Caligiuri, Michael A., Kuo, Calvin J., Yoshimura, Akihiko, Li, Ling, Rockne, Russell C., Kortylewski, Marcin, Zheng, Yi, Carlesso, Nadia, Kuo, Ya-Huei, Marcucci, Guido
Publicado 2021

Acquired miR-142 deficit in leukemic stem cells suffices to drive chronic myeloid leukemia into blast crisis

por Zhang, Bin, Zhao, Dandan, Chen, Fang, Frankhouser, David, Wang, Huafeng, Pathak, Khyatiben V., Dong, Lei, Torres, Anakaren, Garcia-Mansfield, Krystine, Zhang, Yi, Hoang, Dinh Hoa, Chen, Min-Hsuan, Tao, Shu, Cho, Hyejin, Liang, Yong, Perrotti, Danilo, Branciamore, Sergio, Rockne, Russell, Wu, Xiwei, Ghoda, Lucy, Li, Ling, Jin, Jie, Chen, Jianjun, Yu, Jianhua, Caligiuri, Michael A., Kuo, Ya-Huei, Boldin, Mark, Su, Rui, Swiderski, Piotr, Kortylewski, Marcin, Pirrotte, Patrick, Nguyen, Le Xuan Truong, Marcucci, Guido
Publicado 2023