Pivotal vascular homeostatic role for endothelium-derived C-type natriuretic peptide (CNP)

por Hobbs, Adrian J
Publicado 2015

C-Type Natriuretic Peptide: A Multifaceted Paracrine Regulator in the Heart and Vasculature

por Moyes, Amie J., Hobbs, Adrian J.
Publicado 2019

Natriuretic peptide receptor-3 underpins the disparate regulation of endothelial and vascular smooth muscle cell proliferation by C-type natriuretic peptide

por Khambata, Rayomand S, Panayiotou, Catherine M, Hobbs, Adrian J
Publicado 2011

New perspectives for the treatment of pulmonary hypertension

por Baliga, Reshma S, MacAllister, Raymond J, Hobbs, Adrian J
Publicado 2011

Biophysical screening methods for extracellular domain peptide receptors, application to natriuretic peptide receptor C ligands

por Conole, Daniel, Myers, Samuel H., Mota, Filipa, Hobbs, Adrian J., Selwood, David L.
Publicado 2018

Resistance to endotoxic shock in mice lacking natriuretic peptide receptor-A

por Panayiotou, Catherine M, Baliga, Reshma, Stidwill, Raymond, Taylor, Valerie, Singer, Mervyn, Hobbs, Adrian J
Publicado 2010

Hydropersulfides (RSSH) and Nitric Oxide (NO) Signaling: Possible Effects on S-Nitrosothiols (RS-NO)

por Fukuto, Jon M., Perez-Ternero, Cristina, Zarenkiewicz, Jessica, Lin, Joseph, Hobbs, Adrian J., Toscano, John P.
Publicado 2022

Manipulating the natriuretic peptide system for the treatment of pulmonary hypertension

por Baliga, Reshma S, Trinder, Sarah, Scotton, Chris J, Chambers, Rachel C, MacAllister, Raymond J, Hobbs, Adrian J
Publicado 2009

Enhancing natriuretic peptide bioactivity prevents bleomycin-induced pulmonary fibrosis

por Baliga, Reshma S, Trinder, Sarah L, Scotton, Christopher J, Chambers, Rachel C, MacAllister, Raymond J, Hobbs, Adrian J
Publicado 2011

A Series of Substituted Bis-Aminotriazines Are Activators of the Natriuretic Peptide Receptor C

por Smith, Robert J., Perez-Ternero, Cristina, Conole, Daniel, Martin, Capucine, Myers, Samuel H., Hobbs, Adrian J., Selwood, David L.
Publicado 2022

C-type natriuretic peptide preserves central neurological function by maintaining blood-brain barrier integrity

por Perez-Ternero, Cristina, Pallier, Patrick N., Tremoleda, Jordi L., Delogu, Alessio, Fernandes, Cathy, Michael-Titus, Adina T., Hobbs, Adrian J.
Publicado 2022

Characterization of the Human α(1)β(1) Soluble Guanylyl Cyclase Promoter: KEY ROLE FOR NF-κB(p50) AND CCAAT-BINDING FACTORS IN REGULATING EXPRESSION OF THE NITRIC OXIDE RECEPTOR

por Marro, Martín L., Peiró, Concepción, Panayiotou, Catherine M., Baliga, Reshma S., Meurer, Sabine, Schmidt, Harald H. H. W., Hobbs, Adrian J.
Publicado 2008

Investigation of the role of multidrug resistance proteins (MRPs) in vascular homeostasis

por Allen, Robert M H, Renukanthan, Aniruthan, Bubb, Kristen J, Villar, Inmaculada C, Moyes, Amie J, Baliga, Reshma S, Hobbs, Adrian J
Publicado 2015

Natriuretic peptide receptors regulate cytoprotective effects in a human ex vivo 3D/bioreactor model

por Peake, Nicholas, Su, Nyan, Ramachandran, Manoj, Achan, Pramod, Salter, Donald M, Bader, Dan L, Moyes, Amie J, Hobbs, Adrian J, Chowdhury, Tina T
Publicado 2013

Phospholemman Ser69 phosphorylation contributes to sildenafil-induced cardioprotection against reperfusion injury

por Madhani, Melanie, Hall, Andrew R., Cuello, Friederike, Charles, Rebecca L., Burgoyne, Joseph R., Fuller, William, Hobbs, Adrian J., Shattock, Michael J., Eaton, Philip
Publicado 2010

C-type natriuretic peptide is a pivotal regulator of metabolic homeostasis

por Perez-Ternero, Cristina, Aubdool, Aisah A., Makwana, Raj, Sanger, Gareth J., Stimson, Roland H., Chan, Li F., Moyes, Amie J., Hobbs, Adrian J.
Publicado 2022

C-type natriuretic peptide co-ordinates cardiac structure and function

por Moyes, Amie J, Chu, Sandy M, Aubdool, Aisah A, Dukinfield, Matthew S, Margulies, Kenneth B, Bedi, Kenneth C, Hodivala-Dilke, Kairbaan, Baliga, Reshma S, Hobbs, Adrian J
Publicado 2020

Vascular K(ATP) channels protect from cardiac dysfunction and preserve cardiac metabolism during endotoxemia

por Aziz, Qadeer, Chen, Jianmin, Moyes, Amie J, Li, Yiwen, Anderson, Naomi A, Ang, Richard, Aksentijevic, Dunja, Sebastian, Sonia, Hobbs, Adrian J, Thiemermann, Christoph, Tinker, Andrew
Publicado 2020

Phosphodiesterase 2 inhibition preferentially promotes NO/guanylyl cyclase/cGMP signaling to reverse the development of heart failure

por Baliga, Reshma S., Preedy, Michael E. J., Dukinfield, Matthew S., Chu, Sandy M., Aubdool, Aisah A., Bubb, Kristen J., Moyes, Amie J., Tones, Michael A., Hobbs, Adrian J.
Publicado 2018

Cyclic GMP modulating drugs in cardiovascular diseases: mechanism-based network pharmacology

por Petraina, Alexandra, Nogales, Cristian, Krahn, Thomas, Mucke, Hermann, Lüscher, Thomas F, Fischmeister, Rodolphe, Kass, David A, Burnett, John C, Hobbs, Adrian J, Schmidt, Harald H H W
Publicado 2021