Ubiquitin-specific Peptidase 42 (USP42) Functions to Deubiquitylate Histones and Regulate Transcriptional Activity

por Hock, Andreas K., Vigneron, Arnaud M., Vousden, Karen H.
Publicado 2014

p53-mediated adaptation to serine starvation is retained by a common tumour-derived mutant

por Humpton, Timothy J., Hock, Andreas K., Maddocks, Oliver D. K., Vousden, Karen H.
Publicado 2018

iRFP Is a Real Time Marker for Transformation Based Assays in High Content Screening

por Paulus-Hock, Viola, Cheung, Eric C., Roxburgh, Patricia, Vousden, Karen H., Hock, Andreas K.
Publicado 2014

Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity

por Haller, Martina, Hock, Andreas K, Giampazolias, Evangelos, Oberst, Andrew, Green, Douglas R, Debnath, Jayanta, Ryan, Kevin M, Vousden, Karen H, Tait, Stephen W G
Publicado 2015

A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3

por Tajan, Mylène, Hock, Andreas K., Blagih, Julianna, Robertson, Neil A., Labuschagne, Christiaan F., Kruiswijk, Flore, Humpton, Timothy J., Adams, Peter D., Vousden, Karen H.
Publicado 2018

Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice

por Humpton, Timothy J., Nomura, Koji, Weber, Julia, Magnussen, Helge M., Hock, Andreas K., Nixon, Colin, Dhayade, Sandeep, Stevenson, David, Huang, Danny T., Strathdee, Douglas, Blyth, Karen, Vousden, Karen H.
Publicado 2021

A non-invasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo(†)

por Humpton, Timothy J, Hock, Andreas K, Kiourtis, Christos, Donatis, Marco De, Fercoq, Frederic, Nixon, Colin, Bryson, Sheila, Strathdee, Douglas, Carlin, Leo M., Bird, Thomas G., Blyth, Karen, Vousden, Karen H
Publicado 2022

Development of an inducible mouse model of iRFP713 to track recombinase activity and tumour development in vivo

por Hock, Andreas K., Cheung, Eric C., Humpton, Timothy J., Monteverde, Tiziana, Paulus-Hock, Viola, Lee, Pearl, McGhee, Ewan, Scopelliti, Alessandro, Murphy, Daniel J., Strathdee, Douglas, Blyth, Karen, Vousden, Karen H.
Publicado 2017

Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain

por Magnussen, Helge M., Ahmed, Syed F., Sibbet, Gary. J., Hristova, Ventzislava A., Nomura, Koji, Hock, Andreas K., Archibald, Lewis J., Jamieson, Andrew G., Fushman, David, Vousden, Karen H., Weissman, Allan M., Huang, Danny T.
Publicado 2020

Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses

por Blagih, Julianna, Zani, Fabio, Chakravarty, Probir, Hennequart, Marc, Pilley, Steven, Hobor, Sebastijan, Hock, Andreas K., Walton, Josephine B., Morton, Jennifer P., Gronroos, Eva, Mason, Susan, Yang, Ming, McNeish, Iain, Swanton, Charles, Blyth, Karen, Vousden, Karen H.
Publicado 2020

Glutamine Synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma

por Tardito, Saverio, Oudin, Anaïs, Ahmed, Shafiq U., Fack, Fred, Keunen, Olivier, Zheng, Liang, Miletic, Hrvoje, Sakariassen, Per Øystein, Weinstock, Adam, Wagner, Allon, Lindsay, Susan L., Hock, Andreas K., Barnett, Susan C., Ruppin, Eytan, Mørkve, Svein Harald, Lund-Johansen, Morten, Chalmers, Anthony J., Bjerkvig, Rolf, Niclou, Simone P., Gottlieb, Eyal
Publicado 2015

Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy

por Tajan, Mylène, Hennequart, Marc, Cheung, Eric C., Zani, Fabio, Hock, Andreas K., Legrave, Nathalie, Maddocks, Oliver D. K., Ridgway, Rachel A., Athineos, Dimitris, Suárez-Bonnet, Alejandro, Ludwig, Robert L., Novellasdemunt, Laura, Angelis, Nikolaos, Li, Vivian S. W., Vlachogiannis, Georgios, Valeri, Nicola, Mainolfi, Nello, Suri, Vipin, Friedman, Adam, Manfredi, Mark, Blyth, Karen, Sansom, Owen J., Vousden, Karen H.
Publicado 2021