Targeting Immunosuppressive Adenosine Signaling: A Review of Potential Immunotherapy Combination Strategies

por Zahavi, David, Hodge, James W.
Publicado 2023

The emerging role of off-the-shelf engineered natural killer cells in targeted cancer immunotherapy

por Fabian, Kellsye P., Hodge, James W.
Publicado 2021

Natural Born Killers: NK Cells in Cancer Therapy

por Franks, S. Elizabeth, Wolfson, Benjamin, Hodge, James W.
Publicado 2020

Stay on Target: Reengaging Cancer Vaccines in Combination Immunotherapy

por Wolfson, Benjamin, Franks, S. Elizabeth, Hodge, James W.
Publicado 2021

From Immunogenic Cell Death to Immunogenic Modulation: Select Chemotherapy Regimens Induce a Spectrum of Immune-Enhancing Activities in the Tumor Microenvironment

por Fabian, Kellsye P., Wolfson, Benjamin, Hodge, James W.
Publicado 2021

Tipping the scales: Immunotherapeutic strategies that disrupt immunosuppression and promote immune activation

por Santiago-Sánchez, Ginette S., Hodge, James W., Fabian, Kellsye P.
Publicado 2022

Attacking malignant cells that survive therapy: Exploiting immunogenic modulation

por Hodge, James W, Kwilas, Anna, Ardiani, Andressa, Gameiro, Sofia R
Publicado 2013

Radiation-induced survival responses promote immunogenic modulation to enhance immunotherapy in combinatorial regimens

por Gameiro, Sofia R, Ardiani, Andressa, Kwilas, Anna, Hodge, James W
Publicado 2014

Combination therapy with an OX40L fusion protein and a vaccine targeting the transcription factor twist inhibits metastasis in a murine model of breast cancer

por Malamas, Anthony S., Hammond, Scott A., Schlom, Jeffrey, Hodge, James W.
Publicado 2017

Exploiting off-target effects of estrogen deprivation to sensitize estrogen receptor negative breast cancer to immune killing

por Wolfson, Benjamin, Padget, Michelle R, Schlom, Jeffrey, Hodge, James W
Publicado 2021

Dying of Stress: Chemotherapy, Radiotherapy, and Small-Molecule Inhibitors in Immunogenic Cell Death and Immunogenic Modulation

por Fabian, Kellsye P., Kowalczyk, Joshua T., Reynolds, Sandy T., Hodge, James W.
Publicado 2022

Sublethal exposure to alpha radiation ((223)Ra dichloride) enhances various carcinomas’ sensitivity to lysis by antigen-specific cytotoxic T lymphocytes through calreticulin-mediat...

por Malamas, Anthony S., Gameiro, Sofia R., Knudson, Karin M., Hodge, James W.
Publicado 2016

In the field: exploiting the untapped potential of immunogenic modulation by radiation in combination with immunotherapy for the treatment of cancer

por Kwilas, Anna R., Donahue, Renee N., Bernstein, Michael B., Hodge, James W.
Publicado 2012

Dual effects of a targeted small-molecule inhibitor (cabozantinib) on immune-mediated killing of tumor cells and immune tumor microenvironment permissiveness when combined with a c...

por Kwilas, Anna R, Ardiani, Andressa, Donahue, Renee N, Aftab, Dana T, Hodge, James W
Publicado 2014

Androgen deprivation therapy increases the sensitivity of human prostate carcinoma cells to T cell-mediated lysis through an androgen receptor dependent mechanism

por Gameiro, Sofia, Ardiani, Andressa, Kwilas, Anna R, Donahue, Renee N, Hodge, James W
Publicado 2014

Effects of Cabozantinib, a small molecule tyrosine kinase inhibitor, on the immune permissiveness of the tumor microenvironment and immune-mediated killing of tumor cells

por Kwilas, Anna R, Ardiani, Andressa, Donahue, Renee N, Aftab, Dana, Hodge, James W
Publicado 2014

Inhibition of the angiopoietin/Tie2 axis induces immunogenic modulation, which sensitizes human tumor cells to immune attack

por Grenga, Italia, Kwilas, Anna R., Donahue, Renee N., Farsaci, Benedetto, Hodge, James W.
Publicado 2015

Inhibitors of histone deacetylase 1 reverse the immune evasion phenotype to enhance T-cell mediated lysis of prostate and breast carcinoma cells

por Gameiro, Sofia R., Malamas, Anthony S., Tsang, Kwong Y., Ferrone, Soldano, Hodge, James W.
Publicado 2016

Differential combination immunotherapy requirements for inflamed (warm) tumors versus T cell excluded (cool) tumors: engage, expand, enable, and evolve

por Fabian, Kellsye P, Padget, Michelle R, Fujii, Rika, Schlom, Jeffrey, Hodge, James W
Publicado 2021

Immune targeting of three independent suppressive pathways (TIGIT, PD-L1, TGFβ) provides significant antitumor efficacy in immune checkpoint resistant models

por Franks, S. Elizabeth, Fabian, Kellsye P., Santiago-Sánchez, Ginette, Wolfson, Benjamin, Hodge, James W.
Publicado 2022