Absorption, Distribution, and Excretion of (14)C-APX001 after Single-Dose Administration to Rats and Monkeys

por Mansbach, Robert, Shaw, Karen J, Hodges, Michael R, Coleman, Samantha, Fitzsimmons, Michael E
Publicado 2017

1340. Population Pharmacokinetic (PK) Analysis of APX001 Using Phase 1 Data

por Trang, Michael, Bader, Justin C, Ople, Eric A, Kramer, William G, Hodges, Michael R, Bhavnani, Sujata M, Rubino, Christopher M
Publicado 2018

Phase 1b safety and pharmacokinetics of intravenous and oral fosmanogepix in patients with acute myeloid leukaemia and neutropenia

por Cornely, Oliver A, Ostermann, Helmut, Koehler, Philipp, Teschner, Daniel, Limburg, Endrik, Kramer, William G, Barbat, Sara H, Tawadrous, Margaret, Hodges, Michael R
Publicado 2023

Safety and Pharmacokinetics of Intravenous and Oral Fosmanogepix, a First-in-Class Antifungal Agent, in Healthy Volunteers

por Hodges, Michael R., Ople, Eric, Wedel, Pamela, Shaw, Karen J., Jakate, Abhijeet, Kramer, William G., van Marle, Sjoerd, van Hoogdalem, Ewoud-Jan, Tawadrous, Margaret
Publicado 2023

Clinical Efficacy and Safety of a Novel Antifungal, Fosmanogepix, in Patients with Candidemia Caused by Candida auris: Results from a Phase 2 Trial

por Vazquez, Jose A., Pappas, Peter G., Boffard, Kenneth, Paruk, Fathima, Bien, Paul A., Tawadrous, Margaret, Ople, Eric, Wedel, Pamela, Oborska, Iwona, Hodges, Michael R.
Publicado 2023

Quantitative Systems Pharmacology Model of hUGT1A1‐modRNA Encoding for the UGT1A1 Enzyme to Treat Crigler‐Najjar Syndrome Type 1

por Apgar, Joshua F., Tang, Jian‐Ping, Singh, Pratap, Balasubramanian, Nanda, Burke, John, Hodges, Michael R., Lasaro, Melissa A., Lin, Lin, Miliard, Bjorn L., Moore, Kristi, Jun, Lucy S., Sobolov, Susan, Wilkins, Anna Katharina, Gao, Xiang
Publicado 2018

Clinical safety and efficacy of novel antifungal, fosmanogepix, for the treatment of candidaemia: results from a Phase 2 trial

por Pappas, Peter G, Vazquez, Jose A, Oren, Ilana, Rahav, Galia, Aoun, Mickael, Bulpa, Pierre, Ben-Ami, Ronen, Ferrer, Ricard, Mccarty, Todd, Thompson, George R, Schlamm, Haran, Bien, Paul A, Barbat, Sara H, Wedel, Pamela, Oborska, Iwona, Tawadrous, Margaret, Hodges, Michael R
Publicado 2023