Immunohistological Examination of AKT Isoforms in the Brain: Cell-Type Specificity That May Underlie AKT’s Role in Complex Brain Disorders and Neurological Disease

por Levenga, Josien, Wong, Helen, Milstead, Ryan, LaPlante, Lauren, Hoeffer, Charles A
Publicado 2021

AKT isoforms have distinct hippocampal expression and roles in synaptic plasticity

por Levenga, Josien, Wong, Helen, Milstead, Ryan A, Keller, Bailey N, LaPlante, Lauren E, Hoeffer, Charles A
Publicado 2017

Tau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments

por Levenga, Josien, Krishnamurthy, Pavan, Rajamohamedsait, Hameetha, Wong, Helen, Franke, Thomas F, Cain, Peter, Sigurdsson, Einar M, Hoeffer, Charles A
Publicado 2013

The eIF2α kinase PERK limits the expression of hippocampal metabotropic glutamate receptor-dependent long-term depression

por Trinh, Mimi A., Ma, Tao, Kaphzan, Hanoch, Bhattacharya, Aditi, Antion, Marcia D., Cavener, Douglas R., Hoeffer, Charles A., Klann, Eric
Publicado 2014

Transcriptome-wide gene-gene interaction associations elucidate pathways and functional enrichment of complex traits

por Evans, Luke M., Arehart, Christopher H., Grotzinger, Andrew D., Mize, Travis J., Brasher, Maizy S., Stitzel, Jerry A., Ehringer, Marissa A., Hoeffer, Charles A.
Publicado 2023

Dysregulation of the mTOR Pathway Mediates Impairment of Synaptic Plasticity in a Mouse Model of Alzheimer's Disease

por Ma, Tao, Hoeffer, Charles A., Capetillo-Zarate, Estibaliz, Yu, Fangmin, Wong, Helen, Lin, Michael T., Tampellini, Davide, Klann, Eric, Blitzer, Robert D., Gouras, Gunnar K.
Publicado 2010

RCAN1 knockout and overexpression recapitulate an ensemble of rest-activity and circadian disruptions characteristic of Down syndrome, Alzheimer’s disease, and normative aging

por Wong, Helen, Buck, Jordan M., Borski, Curtis, Pafford, Jessica T., Keller, Bailey N., Milstead, Ryan A., Hanson, Jessica L., Stitzel, Jerry A., Hoeffer, Charles A.
Publicado 2022