Genome-wide analysis of pain-, nerve- and neurotrophin -related gene expression in the degenerating human annulus

por Gruber, Helen E, Hoelscher, Gretchen L, Ingram, Jane A, Hanley, Edward N
Publicado 2012

Senescent vs. non-senescent cells in the human annulus in vivo: Cell harvest with laser capture microdissection and gene expression studies with microarray analysis

por Gruber, Helen E, Hoelscher, Gretchen L, Ingram, Jane A, Zinchenko, Natalia, Hanley, Edward N
Publicado 2010

Mucin 1, a signal transduction membrane-bound mucin, is present in human disc tissue and is downregulated in vitro by exposure to IL-1ß or TNF-α

por Gruber, Helen E., Ingram, Jane A., Hoelscher, Gretchen L., Marrero, Emilio, Hanley, Edward N.
Publicado 2017

Asporin, a susceptibility gene in osteoarthritis, is expressed at higher levels in the more degenerate human intervertebral disc

por Gruber, Helen E, Ingram, Jane A, Hoelscher, Gretchen L, Zinchenko, Natalia, Hanley, Edward N, Sun, Yubo
Publicado 2009

Matrix metalloproteinase 28, a novel matrix metalloproteinase, is constitutively expressed in human intervertebral disc tissue and is present in matrix of more degenerated discs

por Gruber, Helen E, Ingram, Jane A, Hoelscher, Gretchen L, Zinchenko, Natalia, Norton, H James, Hanley, Edward N
Publicado 2009

Constitutive expression of cathepsin K in the human intervertebral disc: new insight into disc extracellular matrix remodeling via cathepsin K and receptor activator of nuclear fac...

por Gruber, Helen E, Ingram, Jane A, Hoelscher, Gretchen L, Zinchenko, Natalia, Norton, H James, Hanley, Edward N
Publicado 2011

A Novel Catechol-O-Methyltransferase Variant Associated with Human Disc Degeneration

por Gruber, Helen E., Sha, Wei, Brouwer, Cory R., Steuerwald, Nury, Hoelscher, Gretchen L., Hanley, Edward N. Jr.
Publicado 2014