CDK4/6 and PDGFRA Signaling as Therapeutic Targets in Diffuse Intrinsic Pontine Glioma

por Hoeman, Christine, Shen, Chen, Becher, Oren J.
Publicado 2018

DIPG-24. BRD4 INHIBITION AS A RADIOSENSITIZER THROUGH BLOCKING DNA REPAIR FOR THE TREATMENT OF DIFFUSE MIDLINE GLIOMA

por Watanabe, Jun, Clutter, Matt, Hoeman, Christine, Amreena, Sui, Abe, Koki, Ishi, Yukitomo, Uchida, Eita, Becker, Oren, Hashizume, Rintaro
Publicado 2023

Recovery From Overt Type 1 Diabetes Ensues When Immune Tolerance and β-Cell Formation Are Coupled With Regeneration of Endothelial Cells in the Pancreatic Islets

por Wan, Xiaoxiao, Guloglu, F. Betul, VanMorlan, Amie M., Rowland, Linda M., Zaghouani, Sarah, Cascio, Jason A., Dhakal, Mermagya, Hoeman, Christine M., Zaghouani, Habib
Publicado 2013

Delayed maturation of an IL-12–producing dendritic cell subset explains the early Th2 bias in neonatal immunity

por Lee, Hyun-Hee, Hoeman, Christine M., Hardaway, John C., Guloglu, F. Betul, Ellis, Jason S., Jain, Renu, Divekar, Rohit, Tartar, Danielle M., Haymaker, Cara L., Zaghouani, Habib
Publicado 2008

Innocuous IFNγ induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production

por Jain, Renu, Tartar, Danielle M., Gregg, Randal K., Divekar, Rohit D., Bell, J. Jeremiah, Lee, Hyun-Hee, Yu, Ping, Ellis, Jason S., Hoeman, Christine M., Franklin, Craig L., Zaghouani, Habib
Publicado 2008

Mechanisms Underlying Antigen-Specific Tolerance of Stable and Convertible Th17 Cells During Suppression of Autoimmune Diabetes

por Wan, Xiaoxiao, Guloglu, F. Betul, VanMorlan, Amie M., Rowland, Linda M., Jain, Renu, Haymaker, Cara L., Cascio, Jason A., Dhakal, Mermagya, Hoeman, Christine M., Tartar, Danielle M., Zaghouani, Habib
Publicado 2012

A novel mouse model of diffuse midline glioma initiated in neonatal oligodendrocyte progenitor cells highlights cell‐of‐origin dependent effects of H3K27M

por Tomita, Yusuke, Shimazu, Yosuke, Somasundaram, Agila, Tanaka, Yoshihiro, Takata, Nozomu, Ishi, Yukitomo, Gadd, Samantha, Hashizume, Rintaro, Angione, Angelo, Pinero, Gonzalo, Hambardzumyan, Dolores, Brat, Daniel J., Hoeman, Christine M., Becher, Oren J.
Publicado 2022

A High-Throughput In Vitro Drug Screen in a Genetically Engineered Mouse Model of Diffuse Intrinsic Pontine Glioma Identifies BMS-754807 as a Promising Therapeutic Agent

por Halvorson, Kyle G., Barton, Kelly L., Schroeder, Kristin, Misuraca, Katherine L., Hoeman, Christine, Chung, Alex, Crabtree, Donna M., Cordero, Francisco J., Singh, Raj, Spasojevic, Ivan, Berlow, Noah, Pal, Ranadip, Becher, Oren J.
Publicado 2015

ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis

por Hoeman, Christine M., Cordero, Francisco J., Hu, Guo, Misuraca, Katie, Romero, Megan M., Cardona, Herminio J., Nazarian, Javad, Hashizume, Rintaro, McLendon, Roger, Yu, Paul, Procissi, Daniele, Gadd, Samantha, Becher, Oren J.
Publicado 2019

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

por Buczkowicz, Pawel, Hoeman, Christine, Rakopoulos, Patricia, Pajovic, Sanja, Letourneau, Louis, Dzamba, Misko, Morrison, Andrew, Lewis, Peter, Bouffet, Eric, Bartels, Ute, Zuccaro, Jennifer, Agnihotri, Sameer, Ryall, Scott, Barszczyk, Mark, Chornenkyy, Yevgen, Bourgey, Mathieu, Bourque, Guillaume, Montpetit, Alexandre, Cordero, Francisco, Castelo-Branco, Pedro, Mangerel, Joshua, Tabori, Uri, Ho, King Ching, Huang, Annie, Taylor, Kathryn R., Mackay, Alan, Bendel, Anne E, Nazarian, Javad, Fangusaro, Jason R, Karajannis, Matthias A., Zagzag, David, Foreman, Nicholas K., Donson, Andrew, Hegert, Julia V., Smith, Amy, Chan, Jennifer, Lafay-Cousin, Lucy, Dunn, Sandra, Hukin, Juliette, Dunham, Chris, Scheinemann, Katrin, Michaud, Jean, Zelcer, Shayna, Ramsay, David, Cain, Jason, Brennan, Cameron, Souweidane, Mark M., Jones, Chris, Allis, C. David, Brudno, Michael, Becher, Oren, Hawkins, Cynthia
Publicado 2014