Editorial: Dietary Strategies for Healthy Aging—Caloric Restriction and Beyond

por Hofer, Sebastian J., Davinelli, Sergio
Publicado 2022

Molecular targets of spermidine: implications for cancer suppression

por Zimmermann, Andreas, Hofer, Sebastian J., Madeo, Frank
Publicado 2023

Caloric Restriction Mimetics in Nutrition and Clinical Trials

por Hofer, Sebastian J., Davinelli, Sergio, Bergmann, Martina, Scapagnini, Giovanni, Madeo, Frank
Publicado 2021

The ups and downs of caloric restriction and fasting: from molecular effects to clinical application

por Hofer, Sebastian J, Carmona‐Gutierrez, Didac, Mueller, Melanie I, Madeo, Frank
Publicado 2021

Digesting the crisis: autophagy and coronaviruses

por Carmona-Gutierrez, Didac, Bauer, Maria A., Zimmermann, Andreas, Kainz, Katharina, Hofer, Sebastian J., Kroemer, Guido, Madeo, Frank
Publicado 2020

A hundred spotlights on microbiology: how microorganisms shape our lives

por Carmona-Gutierrez, Didac, Kainz, Katharina, Zimmermann, Andreas, Hofer, Sebastian J., Bauer, Maria A., Ruckenstuhl, Christoph, Kroemer, Guido, Madeo, Frank
Publicado 2022

Spermidine-induced hypusination preserves mitochondrial and cognitive function during aging

por Hofer, Sebastian J., Liang, YongTian, Zimmermann, Andreas, Schroeder, Sabrina, Dengjel, Jörn, Kroemer, Guido, Eisenberg, Tobias, Sigrist, Stephan J., Madeo, Frank
Publicado 2021

Long-term fasting: Multi-system adaptations in humans (GENESIS) study–A single-arm interventional trial

por Grundler, Franziska, Viallon, Magalie, Mesnage, Robin, Ruscica, Massimiliano, von Schacky, Clemens, Madeo, Frank, Hofer, Sebastian J., Mitchell, Sarah J., Croisille, Pierre, Wilhelmi de Toledo, Françoise
Publicado 2022

Novel aspects of age-protection by spermidine supplementation are associated with preserved telomere length

por Wirth, Alexander, Wolf, Bettina, Huang, Cheng-Kai, Glage, Silke, Hofer, Sebastian J., Bankstahl, Marion, Bär, Christian, Thum, Thomas, Kahl, Kai G., Sigrist, Stephan J., Madeo, Frank, Bankstahl, Jens P., Ponimaskin, Evgeni
Publicado 2021

Targeting GATA transcription factors – a novel strategy for anti-aging interventions?

por Zimmermann, Andreas, Kainz, Katharina, Hofer, Sebastian J., Bauer, Maria A., Schroeder, Sabrina, Dengjel, Jörn, Pietrocola, Federico, Kepp, Oliver, Ruckenstuhl, Christoph, Eisenberg, Tobias, Sigrist, Stephan J., Madeo, Frank, Kroemer, Guido, Carmona-Gutierrez, Didac
Publicado 2019

4,4'Dimethoxychalcone: a natural flavonoid that promotes health through autophagy-dependent and -independent effects

por Zimmermann, Andreas, Kainz, Katharina, Hofer, Sebastian J., Bauer, Maria A., Schroeder, Sabrina, Dengjel, Jörn, Pietrocola, Federico, Kepp, Oliver, Ruckenstuhl, Christoph, Eisenberg, Tobias, Sigrist, Stephan J., Madeo, Frank, Carmona-Gutierrez, Didac, Kroemer, Guido
Publicado 2019

Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults With Subjective Cognitive Decline: A Randomized Clinical Trial

por Schwarz, Claudia, Benson, Gloria S., Horn, Nora, Wurdack, Katharina, Grittner, Ulrike, Schilling, Ralph, Märschenz, Stefanie, Köbe, Theresa, Hofer, Sebastian J., Magnes, Christoph, Stekovic, Slaven, Eisenberg, Tobias, Sigrist, Stephan J., Schmitz, Dietmar, Wirth, Miranka, Madeo, Frank, Flöel, Agnes
Publicado 2022

3,4‐Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB

por Chen, Guo, Xie, Wei, Nah, Jihoon, Sauvat, Allan, Liu, Peng, Pietrocola, Federico, Sica, Valentina, Carmona‐Gutierrez, Didac, Zimmermann, Andreas, Pendl, Tobias, Tadic, Jelena, Bergmann, Martina, Hofer, Sebastian J, Domuz, Lana, Lachkar, Sylvie, Markaki, Maria, Tavernarakis, Nektarios, Sadoshima, Junichi, Madeo, Frank, Kepp, Oliver, Kroemer, Guido
Publicado 2019

Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses

por Maglione, Marta, Kochlamazashvili, Gaga, Eisenberg, Tobias, Rácz, Bence, Michael, Eva, Toppe, David, Stumpf, Alexander, Wirth, Alexander, Zeug, André, Müller, Franziska E., Moreno-Velasquez, Laura, Sammons, Rosanna P., Hofer, Sebastian J., Madeo, Frank, Maritzen, Tanja, Maier, Nikolaus, Ponimaskin, Evgeni, Schmitz, Dietmar, Haucke, Volker, Sigrist, Stephan J.
Publicado 2019

Glucose Metabolism and Metabolomic Changes in Response to Prolonged Fasting in Individuals with Obesity, Type 2 Diabetes and Non-Obese People—A Cohort Trial

por Tripolt, Norbert J., Hofer, Sebastian J., Pferschy, Peter N., Aziz, Faisal, Durand, Sylvère, Aprahamian, Fanny, Nirmalathasan, Nitharsshini, Waltenstorfer, Mara, Eisenberg, Tobias, Obermayer, Anna M. A., Riedl, Regina, Kojzar, Harald, Moser, Othmar, Sourij, Caren, Bugger, Heiko, Oulhaj, Abderrahim, Pieber, Thomas R., Zanker, Matthias, Kroemer, Guido, Madeo, Frank, Sourij, Harald
Publicado 2023

Acetyl-CoA carboxylase 1–dependent lipogenesis promotes autophagy downstream of AMPK

por Gross, Angelina S., Zimmermann, Andreas, Pendl, Tobias, Schroeder, Sabrina, Schoenlechner, Hannes, Knittelfelder, Oskar, Lamplmayr, Laura, Santiso, Ana, Aufschnaiter, Andreas, Waltenstorfer, Daniel, Ortonobes Lara, Sandra, Stryeck, Sarah, Kast, Christina, Ruckenstuhl, Christoph, Hofer, Sebastian J., Michelitsch, Birgit, Woelflingseder, Martina, Müller, Rolf, Carmona-Gutierrez, Didac, Madl, Tobias, Büttner, Sabrina, Fröhlich, Kai-Uwe, Shevchenko, Andrej, Eisenberg, Tobias
Publicado 2019

Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity

por Abdellatif, Mahmoud, Trummer-Herbst, Viktoria, Heberle, Alexander Martin, Humnig, Alina, Pendl, Tobias, Durand, Sylvère, Cerrato, Giulia, Hofer, Sebastian J., Islam, Moydul, Voglhuber, Julia, Ramos Pittol, José Miguel, Kepp, Oliver, Hoefler, Gerald, Schmidt, Albrecht, Rainer, Peter P., Scherr, Daniel, von Lewinski, Dirk, Bisping, Egbert, McMullen, Julie R., Diwan, Abhinav, Eisenberg, Tobias, Madeo, Frank, Thedieck, Kathrin, Kroemer, Guido, Sedej, Simon
Publicado 2022

Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models

por Costa-Machado, Luis Filipe, Garcia-Dominguez, Esther, McIntyre, Rebecca L., Lopez-Aceituno, Jose Luis, Ballesteros-Gonzalez, Álvaro, Tapia-Gonzalez, Andrea, Fabregat-Safont, David, Eisenberg, Tobias, Gomez, Jesús, Plaza, Adrian, Sierra-Ramirez, Aranzazu, Perez, Manuel, Villanueva-Bermejo, David, Fornari, Tiziana, Loza, María Isabel, Herradon, Gonzalo, Hofer, Sebastian J., Magnes, Christoph, Madeo, Frank, Duerr, Janet S., Pozo, Oscar J., Galindo, Maximo-Ibo, del Pino, Isabel, Houtkooper, Riekelt H., Megias, Diego, Viña, Jose, Gomez-Cabrera, Mari Carmen, Fernandez-Marcos, Pablo J.
Publicado 2023

The HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity

por Ring, Julia, Tadic, Jelena, Ristic, Selena, Poglitsch, Michael, Bergmann, Martina, Radic, Nemanja, Mossmann, Dirk, Liang, YongTian, Maglione, Marta, Jerkovic, Andrea, Hajiraissi, Roozbeh, Hanke, Marcel, Küttner, Victoria, Wolinski, Heimo, Zimmermann, Andreas, Domuz Trifunović, Lana, Mikolasch, Leonie, Moretti, Daiana N, Broeskamp, Filomena, Westermayer, Julia, Abraham, Claudia, Schauer, Simon, Dammbrueck, Christopher, Hofer, Sebastian J, Abdellatif, Mahmoud, Grundmeier, Guido, Kroemer, Guido, Braun, Ralf J, Hansen, Niklas, Sommer, Cornelia, Ninkovic, Mirjana, Seba, Sandra, Rockenfeller, Patrick, Vögtle, Friederike‐Nora, Dengjel, Jörn, Meisinger, Chris, Keller, Adrian, Sigrist, Stephan J, Eisenberg, Tobias, Madeo, Frank
Publicado 2022

The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species

por Carmona-Gutierrez, Didac, Zimmermann, Andreas, Kainz, Katharina, Pietrocola, Federico, Chen, Guo, Maglioni, Silvia, Schiavi, Alfonso, Nah, Jihoon, Mertel, Sara, Beuschel, Christine B., Castoldi, Francesca, Sica, Valentina, Trausinger, Gert, Raml, Reingard, Sommer, Cornelia, Schroeder, Sabrina, Hofer, Sebastian J., Bauer, Maria A., Pendl, Tobias, Tadic, Jelena, Dammbrueck, Christopher, Hu, Zehan, Ruckenstuhl, Christoph, Eisenberg, Tobias, Durand, Sylvere, Bossut, Noélie, Aprahamian, Fanny, Abdellatif, Mahmoud, Sedej, Simon, Enot, David P., Wolinski, Heimo, Dengjel, Jörn, Kepp, Oliver, Magnes, Christoph, Sinner, Frank, Pieber, Thomas R., Sadoshima, Junichi, Ventura, Natascia, Sigrist, Stephan J., Kroemer, Guido, Madeo, Frank
Publicado 2019