Cannabinoid disruption of learning mechanisms involved in reward processing

por Lupica, Carl R., Hoffman, Alexander F.
Publicado 2018

Optogenetic silencing of a corticotropin-releasing factor pathway from the central amygdala to the bed nucleus of the stria terminalis disrupts sustained fear

por Asok, Arun, Draper, Adam, Hoffman, Alexander F., Schulkin, Jay, Lupica, Carl R., Rosen, Jeffrey B.
Publicado 2017

Silent synapses in selectively activated nucleus accumbens neurons following cocaine-sensitization

por Koya, Eisuke, Cruz, Fabio C., Ator, Robert, Golden, Sam A., Hoffman, Alexander F., Lupica, Carl R., Hope, Bruce T.
Publicado 2012

Single rodent mesohabenular axons release glutamate and GABA

por Root, David H., Mejias-Aponte, Carlos, Zhang, Shiliang, Wang, Huiling, Hoffman, Alexander F., Lupica, Carl R., Morales, Marisela
Publicado 2014

Disruption of hippocampal synaptic transmission and long‐term potentiation by psychoactive synthetic cannabinoid ‘Spice’ compounds: comparison with Δ(9)‐tetrahydrocannabinol...

por Hoffman, Alexander F., Lycas, Matthew D., Kaczmarzyk, Jakub R., Spivak, Charles E., Baumann, Michael H., Lupica, Carl R.
Publicado 2016

A subtle structural modification of a synthetic cannabinoid receptor agonist drastically increases its efficacy at the CB1 receptor

por Yano, Hideaki, Chitsazi, Rezvan, Lucaj, Christopher, Tran, Phuong, Hoffman, Alexander F., Baumann, Michael H., Lupica, Carl R., Shi, Lei
Publicado 2023

Subtle Structural Modification of a Synthetic Cannabinoid Receptor Agonist Drastically Increases its Efficacy at the CB1 Receptor

por Yano, Hideaki, Chitsazi, Rezvan, Lucaj, Christopher, Tran, Phuong, Hoffman, Alexander F., Baumann, Michael H., Lupica, Carl R., Shi, Lei
Publicado 2023

Orbitofrontal activation restores insight lost after cocaine use

por Lucantonio, Federica, Takahashi, Yuji, Hoffman, Alexander F, Chang, Chun Y, Chaudhary, Sheena, Shaham, Yavin, Lupica, Carl R, Schoenbaum, Geoffrey
Publicado 2014

Reversing anterior insular cortex neuronal hypoexcitability attenuates compulsive behavior in adolescent rats

por Jadhav, Kshitij S., Bernheim, Aurélien P., Aeschlimann, Léa, Kirschmann, Guylène, Decosterd, Isabelle, Hoffman, Alexander F., Lupica, Carl R., Boutrel, Benjamin
Publicado 2022

Novel and Potent Dopamine D(2) Receptor Go-Protein Biased Agonists

por Bonifazi, Alessandro, Yano, Hideaki, Guerrero, Adrian M., Kumar, Vivek, Hoffman, Alexander F., Lupica, Carl R., Shi, Lei, Newman, Amy Hauck
Publicado 2019

Dopaminergic and glutamatergic microdomains within a subset of rodent mesoaccumbens axons

por Zhang, Shiliang, Qi, Jia, Li, Xueping, Wang, Hui-Ling, Britt, Jonathan P., Hoffman, Alexander F., Bonci, Antonello, Lupica, Carl R., Morales, Marisela
Publicado 2015

Gs- versus Golf-dependent functional selectivity mediated by the dopamine D(1) receptor

por Yano, Hideaki, Cai, Ning-Sheng, Xu, Min, Verma, Ravi Kumar, Rea, William, Hoffman, Alexander F., Shi, Lei, Javitch, Jonathan A., Bonci, Antonello, Ferré, Sergi
Publicado 2018

A glutamatergic reward input from the dorsal raphe to ventral tegmental area dopamine neurons

por Qi, Jia, Zhang, Shiliang, Wang, Hui-Ling, Wang, Huikun, de Jesus Aceves Buendia, Jose, Hoffman, Alexander F., Lupica, Carl R., Seal, Rebecca P., Morales, Marisela
Publicado 2014

Effects of Withdrawal from Cocaine Self-Administration on Rat Orbitofrontal Cortex Parvalbumin Neurons Expressing Cre recombinase: Sex-Dependent Changes in Neuronal Function and Un...

por Wright, Andrew M., Zapata, Agustin, Hoffman, Alexander F., Necarsulmer, Julie C., Coke, Lamarque M., Svarcbahs, Reinis, Richie, Christopher T., Pickel, James, Hope, Bruce T., Harvey, Brandon K., Lupica, Carl R.
Publicado 2021

PTEN deletion enhances survival, neurite outgrowth and function of dopamine neuron grafts to MitoPark mice

por Zhang, YaJun, Granholm, Ann-Charlotte, Huh, Kyounghee, Shan, Lufei, Diaz-Ruiz, Oscar, Malik, Nasir, Olson, Lars, Hoffer, Barry J., Lupica, Carl R., Hoffman, Alexander F., Bäckman, Cristina M.
Publicado 2012

NMDA Receptors on Non-Dopaminergic Neurons in the VTA Support Cocaine Sensitization

por Luo, Yu, Good, Cameron H., Diaz-Ruiz, Oscar, Zhang, YaJun, Hoffman, Alexander F., Shan, Lufei, Kuang, Serena Y., Malik, Nasir, Chefer, Vladimir I., Tomac, Andreas C., Lupica, Carl R., Bäckman, Cristina M.
Publicado 2010

Persistent binding at dopamine transporters determines sustained psychostimulant effects

por Niello, Marco, Sideromenos, Spyridon, Gradisch, Ralph, O´Shea, Ronan, Schwazer, Jakob, Maier, Julian, Kastner, Nina, Sandtner, Walter, Jäntsch, Kathrin, Lupica, Carl R., Hoffman, Alexander F., Lubec, Gert, Loland, Claus J., Stockner, Thomas, Pollak, Daniela D., Baumann, Michael H., Sitte, Harald H.
Publicado 2023

Striatal Rgs4 regulates feeding and susceptibility to diet-induced obesity

por Michaelides, Michael, Miller, Michael L., Egervari, Gabor, Primeaux, Stefany D., Gomez, Juan L., Ellis, Randall J., Landry, Joseph A., Szutorisz, Henrietta, Hoffman, Alexander F., Lupica, Carl R., Loos, Ruth J.F., Thanos, Panayotis K., Bray, George A., Neumaier, John F., Zachariou, Venetia, Wang, Gene-Jack, Volkow, Nora D., Hurd, Yasmin L.
Publicado 2018