Correcting for Population Structure and Kinship Using the Linear Mixed Model: Theory and Extensions

por Hoffman, Gabriel E.
Publicado 2013

Correction: Correcting for Population Structure and Kinship Using the Linear Mixed Model: Theory and Extensions

por Hoffman, Gabriel E.
Publicado 2013

variancePartition: interpreting drivers of variation in complex gene expression studies

por Hoffman, Gabriel E., Schadt, Eric E.
Publicado 2016

A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis

por Logsdon, Benjamin A, Hoffman, Gabriel E, Mezey, Jason G
Publicado 2010

Mouse obesity network reconstruction with a variational Bayes algorithm to employ aggressive false positive control

por Logsdon, Benjamin A, Hoffman, Gabriel E, Mezey, Jason G
Publicado 2012

PUMA: A Unified Framework for Penalized Multiple Regression Analysis of GWAS Data

por Hoffman, Gabriel E., Logsdon, Benjamin A., Mezey, Jason G.
Publicado 2013

Evolution of light-harvesting complex proteins from Chl c-containing algae

por Hoffman, Gabriel E, Sanchez-Puerta, M Virginia, Delwiche, Charles F
Publicado 2011

New considerations for hiPSC-based models of neuropsychiatric disorders

por Hoffman, Gabriel E., Schrode, Nadine, Flaherty, Erin, Brennand, Kristen J.
Publicado 2018

Functional interpretation of genetic variants using deep learning predicts impact on chromatin accessibility and histone modification

por Hoffman, Gabriel E, Bendl, Jaroslav, Girdhar, Kiran, Schadt, Eric E, Roussos, Panos
Publicado 2019

Transcriptional signatures of participant-derived neural progenitor cells and neurons implicate altered Wnt signaling in Phelan-McDermid syndrome and autism

por Breen, Michael S., Browne, Andrew, Hoffman, Gabriel E., Stathopoulos, Sofia, Brennand, Kristen, Buxbaum, Joseph D., Drapeau, Elodie
Publicado 2020

Merged Affinity Network Association Clustering: Joint multi-omic/clinical clustering to identify disease endotypes

por Tyler, Scott R., Chun, Yoojin, Ribeiro, Victoria M., Grishina, Galina, Grishin, Alexander, Hoffman, Gabriel E., Do, Anh N., Bunyavanich, Supinda
Publicado 2021

A Nasal Brush-based Classifier of Asthma Identified by Machine Learning Analysis of Nasal RNA Sequence Data

por Pandey, Gaurav, Pandey, Om P., Rogers, Angela J., Ahsen, Mehmet E., Hoffman, Gabriel E., Raby, Benjamin A., Weiss, Scott T., Schadt, Eric E., Bunyavanich, Supinda
Publicado 2018

DeepGAMI: deep biologically guided auxiliary learning for multimodal integration and imputation to improve genotype–phenotype prediction

por Chandrashekar, Pramod Bharadwaj, Alatkar, Sayali, Wang, Jiebiao, Hoffman, Gabriel E., He, Chenfeng, Jin, Ting, Khullar, Saniya, Bendl, Jaroslav, Fullard, John F., Roussos, Panos, Wang, Daifeng
Publicado 2023

Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains

por Hoffman, Gabriel E., Hartley, Brigham J., Flaherty, Erin, Ladran, Ian, Gochman, Peter, Ruderfer, Douglas M., Stahl, Eli A., Rapoport, Judith, Sklar, Pamela, Brennand, Kristen J.
Publicado 2017

Global landscape and genetic regulation of RNA editing in cortical samples from individuals with schizophrenia

por Breen, Michael S., Dobbyn, Amanda, Li, Qin, Roussos, Panos, Hoffman, Gabriel E., Stahl, Eli, Chess, Andrew, Sklar, Pamela, Li, Jin Billy, Devlin, Bernie, Buxbaum, Joseph D.
Publicado 2019

Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits

por Zhang, Wen, Voloudakis, Georgios, Rajagopal, Veera M., Readhead, Ben, Dudley, Joel T., Schadt, Eric E., Björkegren, Johan L. M., Kim, Yungil, Fullard, John F., Hoffman, Gabriel E., Roussos, Panos
Publicado 2019

Four Loci Explain 83% of Size Variation in the Horse

por Makvandi-Nejad, Shokouh, Hoffman, Gabriel E., Allen, Jeremy J., Chu, Erin, Gu, Esther, Chandler, Alyssa M., Loredo, Ariel I., Bellone, Rebecca R., Mezey, Jason G., Brooks, Samantha A., Sutter, Nathan B.
Publicado 2012

Efficient differential expression analysis of large-scale single cell transcriptomics data using dreamlet

por Hoffman, Gabriel E., Lee, Donghoon, Bendl, Jaroslav, Fnu, Prashant, Hong, Aram, Casey, Clara, Alvia, Marcela, Shao, Zhiping, Argyriou, Stathis, Therrien, Karen, Venkatesh, Sanan, Voloudakis, Georgios, Haroutunian, Vahram, Fullard, John F., Roussos, Panos
Publicado 2023

Efficient differential expression analysis of large-scale single cell transcriptomics data using dreamlet

por Hoffman, Gabriel E., Lee, Donghoon, Bendl, Jaroslav, Fnu, Prashant, Hong, Aram, Casey, Clara, Alvia, Marcela, Shao, Zhiping, Argyriou, Stathis, Therrien, Karen, Venkatesh, Sanan, Voloudakis, Georgios, Haroutunian, Vahram, Fullard, John F., Roussos, Panos
Publicado 2023

Genetic regulation of cell-type specific chromatin accessibility shapes the etiology of brain diseases

por Zeng, Biao, Bendl, Jaroslav, Deng, Chengyu, Lee, Donghoon, Misir, Ruth, Reach, Sarah M., Kleopoulos, Steven P., Auluck, Pavan, Marenco, Stefano, Lewis, David A., Haroutunian, Vahram, Ahituv, Nadav, Fullard, John F., Hoffman, Gabriel E., Roussos, Panos
Publicado 2023