IL-1 and autoinflammatory disease: biology, pathogenesis and therapeutic targeting

por Broderick, Lori, Hoffman, Hal M.
Publicado 2022

Inflammasome and IL-1β-Mediated Disorders

por Hoffman, Hal M., Wanderer, Alan A.
Publicado 2010

Association between celiac sprue and cryopyrin associated autoinflammatory disorders: a case report

por Shaker, Marcus, Edwards, Susan, Chionuma, Henry, Shamansky, Eric, Hoffman, Hal M
Publicado 2007

Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity

por Liu, George Y., Essex, Anthony, Buchanan, John T., Datta, Vivekanand, Hoffman, Hal M., Bastian, John F., Fierer, Joshua, Nizet, Victor
Publicado 2005

Increased Neutrophil Secretion Induced by NLRP3 Mutation Links the Inflammasome to Azurophilic Granule Exocytosis

por Johnson, Jennifer L., Ramadass, Mahalakshmi, Haimovich, Ariela, McGeough, Matthew D., Zhang, Jinzhong, Hoffman, Hal M., Catz, Sergio D.
Publicado 2017

The role of IL-1 in adipose browning and muscle wasting in CKD-associated cachexia

por Cheung, Wai W., Zheng, Ronghao, Hao, Sheng, Wang, Zhen, Gonzalez, Alex, Zhou, Ping, Hoffman, Hal M., Mak, Robert H.
Publicado 2021

Targeting interleukin‐1 for reversing fat browning and muscle wasting in infantile nephropathic cystinosis

por Cheung, Wai W., Hao, Sheng, Zheng, Ronghao, Wang, Zhen, Gonzalez, Alex, Zhou, Ping, Hoffman, Hal M., Mak, Robert H.
Publicado 2021

RNA Sequencing Reveals Beneficial Effects of Atorvastatin on Endothelial Cells in Acute Kawasaki Disease

por Shimizu, Chisato, Kim, Jihoon, He, Ming, Tremoulet, Adriana H., Hoffman, Hal M., Shyy, John Y‐J., Burns, Jane C.
Publicado 2022

A Group A Streptococcus ADP-Ribosyltransferase Toxin Stimulates a Protective Interleukin 1β-Dependent Macrophage Immune Response

por Lin, Ann E., Beasley, Federico C., Keller, Nadia, Hollands, Andrew, Urbano, Rodolfo, Troemel, Emily R., Hoffman, Hal M., Nizet, Victor
Publicado 2015

Differential Binding of NLRP3 to non-oxidized and Ox-mtDNA mediates NLRP3 Inflammasome Activation

por Cabral, Angela, Cabral, Julia Elise, Wang, Angelina, Zhang, Yiyang, Liang, Hailin, Nikbakht, Donya, Corona, Leslie, Hoffman, Hal M., McNulty, Reginald
Publicado 2023

Author Correction: Differential binding of NLRP3 to non-oxidized and Ox-mtDNA mediates NLRP3 Inflammasome Activation

por Cabral, Angela, Cabral, Julia Elise, Wang, Angelina, Zhang, Yiyang, Liang, Hailin, Nikbakht, Donya, Corona, Leslie, Hoffman, Hal M., McNulty, Reginald
Publicado 2023

Endothelial Cell Response in Kawasaki Disease and Multisystem Inflammatory Syndrome in Children

por Kim, Jihoon, Shimizu, Chisato, He, Ming, Wang, Hao, Hoffman, Hal M., Tremoulet, Adriana H., Shyy, John Y.-J., Burns, Jane C.
Publicado 2023

Differential Immune Activation in Fetal Macrophage Populations

por Lakhdari, Omar, Yamamura, Asami, Hernandez, Gilberto E., Anderson, Kathryn K., Lund, Sean J., Oppong-Nonterah, Gertrude O., Hoffman, Hal M., Prince, Lawrence S.
Publicado 2019

Partial Jacobsen syndrome phenotype in a patient with a de novo frameshift mutation in the ETS1 transcription factor

por Tootleman, Eva, Malamut, Barbara, Akshoomoff, Natacha, Mattson, Sarah N., Hoffman, Hal M., Jones, Marilyn C., Printz, Beth, Shiryaev, Sergey A., Grossfeld, Paul
Publicado 2019

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

por Lamkanfi, Mohamed, Mueller, James L., Vitari, Alberto C., Misaghi, Shahram, Fedorova, Anna, Deshayes, Kurt, Lee, Wyne P., Hoffman, Hal M., Dixit, Vishva M.
Publicado 2009

Methodological challenges in monitoring new treatments for rare diseases: lessons from the cryopyrin-associated periodic syndrome registry

por Tilson, Hugh, Primatesta, Paola, Kim, Dennis, Rauer, Barbara, Hawkins, Philip N, Hoffman, Hal M, Kuemmerle-Deschner, Jasmin, van der Poll, Tom, Walker, Ulrich A
Publicado 2013

Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9–driven antiinflammatory cytokine production

por González-Navajas, Jose M., Law, Jason, Nguyen, Kim Phung, Bhargava, Meha, Corr, Mary Patricia, Varki, Nissi, Eckmann, Lars, Hoffman, Hal M., Lee, Jongdae, Raz, Eyal
Publicado 2010

The TGFβ1 Promoter SNP C-509T and Food Sensitization Promote Esophageal Remodeling in Pediatric Eosinophilic Esophagitis

por Rawson, Renee, Anilkumar, Arjun, Newbury, Robert O., Bafna, Vineet, Aquino, Melissa, Palmquist, Jacob, Hoffman, Hal M., Mueller, James L., Dohil, Ranjan, . Broide, David H, Aceves, Seema S.
Publicado 2015

Long-term safety and effectiveness of canakinumab therapy in patients with cryopyrin-associated periodic syndrome: results from the β-Confident Registry

por Walker, Ulrich A, Tilson, Hugh H, Hawkins, Philip N, van der Poll, Tom, Noviello, Stephanie, Levy, Jeremy, Vritzali, Eleni, Hoffman, Hal M, Kuemmerle-Deschner, Jasmin B
Publicado 2021

Cell-specific Deletion of NLRP3 Inflammasome Identifies Myeloid Cells as Key Drivers of Liver Inflammation and Fibrosis in Murine Steatohepatitis

por Kaufmann, Benedikt, Kui, Lin, Reca, Agustina, Leszczynska, Aleksandra, Kim, Andrea D., Booshehri, Laela M., Wree, Alexander, Friess, Helmut, Hartmann, Daniel, Broderick, Lori, Hoffman, Hal M., Feldstein, Ariel E.
Publicado 2022