The Heritability of Replication Problems

por Hoffmann, Jean-Sébastien
Publicado 2021

Pol κ in replication checkpoint

por Maiorano, Domenico, Hoffmann, Jean-Sébastien
Publicado 2013

When RAD52 Allows Mitosis to Accept Unscheduled DNA Synthesis

por Franchet, Camille, Hoffmann, Jean-Sébastien
Publicado 2019

The Protective Role of Dormant Origins in Response to Replicative Stress

por Courtot, Lilas, Hoffmann, Jean-Sébastien, Bergoglio, Valérie
Publicado 2018

Recent Advances in Enhancing the Therapeutic Index of PARP Inhibitors in Breast Cancer

por Franchet, Camille, Hoffmann, Jean-Sébastien, Dalenc, Florence
Publicado 2021

Impact of the DNA polymerase Theta on the DNA replication program

por Baldacci, Giuseppe, Hoffmann, Jean-Sebastien, Cadoret, Jean-Charles
Publicado 2014

Role of DNA polymerase κ in the maintenance of genomic stability

por Pillaire, Marie-Jeanne, Bétous, Rémy, Hoffmann, Jean-Sébastien
Publicado 2014

Under-Replicated DNA: The Byproduct of Large Genomes?

por Bertolin, Agustina P., Hoffmann, Jean-Sébastien, Gottifredi, Vanesa
Publicado 2020

Translesion Synthesis or Repair by Specialized DNA Polymerases Limits Excessive Genomic Instability upon Replication Stress

por Maiorano, Domenico, El Etri, Jana, Franchet, Camille, Hoffmann, Jean-Sébastien
Publicado 2021

Involvement of DNA polymerase μ in the repair of a specific subset of DNA double-strand breaks in mammalian cells

por Capp, Jean-Pascal, Boudsocq, François, Besnard, Anne-Gaelle, Lopez, Bernard S., Cazaux, Christophe, Hoffmann, Jean-Sébastien, Canitrot, Yvan
Publicado 2007

A DNA repair variant in POLQ (c.-1060A > G) is associated to hereditary breast cancer patients: a case–control study

por Brandalize, Ana Paula Carneiro, Schüler-Faccini, Lavínia, Hoffmann, Jean-Sébastien, Caleffi, Maira, Cazaux, Christophe, Ashton-Prolla, Patricia
Publicado 2014

MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells

por Lai, Xianning, Broderick, Ronan, Bergoglio, Valérie, Zimmer, Jutta, Badie, Sophie, Niedzwiedz, Wojciech, Hoffmann, Jean-Sébastien, Tarsounas, Madalena
Publicado 2017

Corrigendum: MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells

por Lai, Xianning, Broderick, Ronan, Bergoglio, Valérie, Zimmer, Jutta, Badie, Sophie, Niedzwiedz, Wojciech, Hoffmann, Jean-Sébastien, Tarsounas, Madalena
Publicado 2017

DNA replication stress triggers rapid DNA replication fork breakage by Artemis and XPF

por Bétous, Rémy, Goullet de Rugy, Théo, Pelegrini, Alessandra Luiza, Queille, Sophie, de Villartay, Jean-Pierre, Hoffmann, Jean-Sébastien
Publicado 2018

Exploring the basis of heterogeneity of cancer aggressiveness among the mutated POLE variants

por Selves, Janick, de Castro e Gloria, Helena, Brunac, Anne-Cécile, Saffi, Jenifer, Guimbaud, Rosine, Brousset, Pierre, Hoffmann, Jean-Sébastien
Publicado 2023

Analyzing the Opportunities to Target DNA Double-Strand Breaks Repair and Replicative Stress Responses to Improve Therapeutic Index of Colorectal Cancer

por Tomasini, Paula Pellenz, Guecheva, Temenouga Nikolova, Leguisamo, Natalia Motta, Péricart, Sarah, Brunac, Anne-Cécile, Hoffmann, Jean Sébastien, Saffi, Jenifer
Publicado 2021

Human Adipose‐Derived Stem Cells Expanded Under Ambient Oxygen Concentration Accumulate Oxidative DNA Lesions and Experience Procarcinogenic DNA Replication Stress

por Bétous, Rémy, Renoud, Marie‐Laure, Hoede, Claire, Gonzalez, Ignacio, Jones, Natalie, Longy, Michel, Sensebé, Luc, Cazaux, Christophe, Hoffmann, Jean‐Sébastien
Publicado 2016

KDM5A and KDM5B histone-demethylases contribute to HU-induced replication stress response and tolerance

por Gaillard, Solenne, Charasson, Virginie, Ribeyre, Cyril, Salifou, Kader, Pillaire, Marie-Jeanne, Hoffmann, Jean-Sebastien, Constantinou, Angelos, Trouche, Didier, Vandromme, Marie
Publicado 2021

Depletion of DNA Polymerase Theta Inhibits Tumor Growth and Promotes Genome Instability through the cGAS-STING-ISG Pathway in Esophageal Squamous Cell Carcinoma

por Li, Jian, Ko, Josephine Mun-Yee, Dai, Wei, Yu, Valen Zhuoyou, Ng, Hoi Yan, Hoffmann, Jean-Sébastien, Lung, Maria Li
Publicado 2021

The DNA polymerase λ is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells

por Capp, Jean-Pascal, Boudsocq, François, Bertrand, Pascale, Laroche-Clary, Audrey, Pourquier, Philippe, Lopez, Bernard S., Cazaux, Christophe, Hoffmann, Jean-Sébastien, Canitrot, Yvan
Publicado 2006