NEO212: sub-cytotoxic doses capable of inhibiting glioma stem cell invasion

por Marín-Ramos, Nagore I., Hofman, Florence M., Chen, Thomas C.
Publicado 2018

Distribution of cancer stem cells in two human brain gliomas

por Peng, Lilei, Fu, Jie, Wang, Weijun, Hofman, Florence M., Chen, Thomas C., Chen, Ligang
Publicado 2019

Rare Stochastic Expression of O6-Methylguanine- DNA Methyltransferase (MGMT) in MGMT-Negative Melanoma Cells Determines Immediate Emergence of Drug-Resistant Populations upon Treat...

por Chen, Thomas C., Chan, Nymph, Minea, Radu O., Hartman, Hannah, Hofman, Florence M., Schönthal, Axel H.
Publicado 2018

Breast Cancer MDA-MB-231 Cells Use Secreted Heat Shock Protein-90alpha (Hsp90α) to Survive a Hostile Hypoxic Environment

por Dong, Hangming, Zou, Mengchen, Bhatia, Ayesha, Jayaprakash, Priyamvada, Hofman, Florence, Ying, Qilong, Chen, Mei, Woodley, David T., Li, Wei
Publicado 2016

Induction of Pro-Apoptotic Endoplasmic Reticulum Stress in Multiple Myeloma Cells by NEO214, Perillyl Alcohol Conjugated to Rolipram

por Chen, Thomas C., Chan, Nymph, Labib, Shirin, Yu, Jiali, Cho, Hee-Yeon, Hofman, Florence M., Schönthal, Axel H.
Publicado 2018

Argonaute‐2 Promotes miR‐18a Entry in Human Brain Endothelial Cells

por Ferreira, Raquel, Santos, Tiago, Amar, Arun, Gong, Alex, Chen, Thomas C., Tahara, Stanley M., Giannotta, Steven L., Hofman, Florence M.
Publicado 2014

Heterocellular Contacts with Mouse Brain Endothelial Cells Via Laminin and α6β1 Integrin Sustain Subventricular Zone (SVZ) Stem/Progenitor Cells Properties

por Rosa, Alexandra I., Grade, Sofia, Santos, Sofia D., Bernardino, Liliana, Chen, Thomas C., Relvas, João, Hofman, Florence M., Agasse, Fabienne
Publicado 2016

Chemotherapeutic effect of a novel temozolomide analog on nasopharyngeal carcinoma in vitro and in vivo

por Chen, Thomas C., Cho, Hee-Yeon, Wang, Weijun, Wetzel, Stephanie J., Singh, Anupam, Nguyen, Jenny, Hofman, Florence M., Schönthal, Axel H.
Publicado 2015

NEO412: A temozolomide analog with transdermal activity in melanoma in vitro and in vivo

por Swenson, Steve, Silva-Hirschberg, Catalina, Wang, Weijun, Singh, Anupam, Hofman, Florence M., Chen, Kristen L., Schönthal, Axel H., Chen, Thomas C.
Publicado 2018

Development of immune memory to glial brain tumors after tumor regression induced by immunotherapeutic Toll-like receptor 7/8 activation

por Stathopoulos, Apostolis, Pretto, Chrystel, Devillers, Laurent, Pierre, Denis, Hofman, Florence M., Kruse, Carol, Jadus, Martin, Chen, Thomas C., Schijns, Virgil E.J.C.
Publicado 2012

Repositioning of Verrucosidin, a Purported Inhibitor of Chaperone Protein GRP78, as an Inhibitor of Mitochondrial Electron Transport Chain Complex I

por Thomas, Simmy, Sharma, Natasha, Gonzalez, Reyna, Pao, Peng-Wen, Hofman, Florence M., Chen, Thomas C., Louie, Stan G., Pirrung, Michael C., Schönthal, Axel H.
Publicado 2013

Sequential Administration of Carbon Nanotubes and Near-Infrared Radiation for the Treatment of Gliomas

por Santos, Tiago, Fang, Xin, Chen, Meng-Tse, Wang, Weijun, Ferreira, Raquel, Jhaveri, Niyati, Gundersen, Martin, Zhou, Chongwu, Pagnini, Paul, Hofman, Florence M., Chen, Thomas C.
Publicado 2014

Developing a clinically relevant radiosensitizer for temozolomide-resistant gliomas

por Minea, Radu O., Duc, Tuan Cao, Swenson, Stephen D., Cho, Hee-Yeon, Huang, Mickey, Hartman, Hannah, Hofman, Florence M., Schönthal, Axel H., Chen, Thomas C.
Publicado 2020

Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells i...

por Pyrko, Peter, Soriano, Nathaniel, Kardosh, Adel, Liu, Yen-Ting, Uddin, Jasim, Petasis, Nicos A, Hofman, Florence M, Chen, Ching-Shih, Chen, Thomas C, Schönthal, Axel H
Publicado 2006

First clinical results of a personalized immunotherapeutic vaccine against recurrent, incompletely resected, treatment-resistant glioblastoma multiforme (GBM) tumors, based on comb...

por Schijns, Virgil E.J.C., Pretto, Chrystel, Devillers, Laurent, Pierre, Denis, Hofman, Florence M., Chen, Thomas C., Mespouille, Pascal, Hantos, Peter, Glorieux, Philippe, Bota, Daniela A., Stathopoulos, Apostolos
Publicado 2015

Pharmacokinetic properties of the temozolomide perillyl alcohol conjugate (NEO212) in mice

por Cho, Hee-Yeon, Swenson, Steve, Thein, Thu Zan, Wang, Weijun, Wijeratne, Neloni R, Marín-Ramos, Nagore I, Katz, Jonathan E, Hofman, Florence M, Schönthal, Axel H, Chen, Thomas C
Publicado 2020

Exploring the Therapeutic Efficacy of Glioma Vaccines Based on Allo- and Syngeneic Antigens and Distinct Immunological Costimulation Activators

por Stathopoulos, Apostolos, Pretto, Chrystel, Devillers, Laurent, Pierre, Denis, Hofman, Florence M., Epstein, Alan L., Farghadani, Hooman, Kruse, Carol A., Jadus, Martin R., Chen, Thomas C., Schijns, Virgil E.J.C.
Publicado 2012

Monoamine oxidase A (MAO A) inhibitors decrease glioma progression

por Kushal, Swati, Wang, Weijun, Vaikari, Vijaya Pooja, Kota, Rajesh, Chen, Kevin, Yeh, Tzu-Shao, Jhaveri, Niyati, Groshen, Susan L., Olenyuk, Bogdan Z., Chen, Thomas C., Hofman, Florence M., Shih, Jean C.
Publicado 2016

Phase II study of ERC1671 plus bevacizumab versus bevacizumab plus placebo in recurrent glioblastoma: interim results and correlations with CD4(+) T-lymphocyte counts

por Bota, Daniela A, Chung, Jinah, Dandekar, Manisha, Carrillo, Jose A, Kong, Xiao-Tang, Fu, Beverly D, Hsu, Frank PK, Schönthal, Axel H, Hofman, Florence M, Chen, Thomas C, Zidovetzki, Raphael, Pretto, Chrystel, Strik, Ankie, Schijns, Virgil EJC, Stathopoulos, Apostolos
Publicado 2018

Therapeutic Immunization against Glioblastoma

por Schijns, Virgil E. J. C., Pretto, Chrystel, Strik, Anna M., Gloudemans-Rijkers, Rianne, Devillers, Laurent, Pierre, Denis, Chung, Jinah, Dandekar, Manisha, Carrillo, Jose A., Kong, Xiao-Tang, Fu, Beverly D., Hsu, Frank P. K., Hofman, Florence M., Chen, Thomas C., Zidovetzki, Raphael, Bota, Daniela A., Stathopoulos, Apostolos
Publicado 2018