Structure and dynamics of pteridine reductase 1: the key phenomena relevant to enzyme function and drug design

por Panecka-Hofman, Joanna, Poehner, Ina
Publicado 2023

Application of a simple quantum chemical approach to ligand fragment scoring for Trypanosoma brucei pteridine reductase 1 inhibition

por Jedwabny, Wiktoria, Panecka-Hofman, Joanna, Dyguda-Kazimierowicz, Edyta, Wade, Rebecca C., Sokalski, W. Andrzej
Publicado 2017

Substrate-Based Design of Cytosolic Nucleotidase IIIB Inhibitors and Structural Insights into Inhibition Mechanism

por Kubacka, Dorota, Kozarski, Mateusz, Baranowski, Marek R., Wojcik, Radoslaw, Panecka-Hofman, Joanna, Strzelecka, Dominika, Basquin, Jerome, Jemielity, Jacek, Kowalska, Joanna
Publicado 2022

An engineered variant of MECR reductase reveals indispensability of long-chain acyl-ACPs for mitochondrial respiration

por Tanvir Rahman, M., Kristian Koski, M., Panecka-Hofman, Joanna, Schmitz, Werner, Kastaniotis, Alexander J., Wade, Rebecca C., Wierenga, Rik K., Kalervo Hiltunen, J., Autio, Kaija J.
Publicado 2023

Evaluation of an organisational-level monetary incentive to promote the health and wellbeing of workers in small and medium-sized enterprises: A mixed-methods cluster randomised co...

por Al-Khudairy, Lena, Akram, Yasmin, Watson, Samuel I., Kudrna, Laura, Hofman, Joanna, Nightingale, Madeline, Alidu, Lailah, Rudge, Andrew, Rawdin, Clare, Ghosh, Iman, Mason, Frances, Perera, Chinthana, Wright, Jane, Boachie, Joseph, Hemming, Karla, Vlaev, Ivo, Russell, Sean, Lilford, Richard J.
Publicado 2023

Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1

por Pöhner, Ina, Quotadamo, Antonio, Panecka-Hofman, Joanna, Luciani, Rosaria, Santucci, Matteo, Linciano, Pasquale, Landi, Giacomo, Di Pisa, Flavio, Dello Iacono, Lucia, Pozzi, Cecilia, Mangani, Stefano, Gul, Sheraz, Witt, Gesa, Ellinger, Bernhard, Kuzikov, Maria, Santarem, Nuno, Cordeiro-da-Silva, Anabela, Costi, Maria P., Venturelli, Alberto, Wade, Rebecca C.
Publicado 2022

Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform

por Moraes, Carolina B., Witt, Gesa, Kuzikov, Maria, Ellinger, Bernhard, Calogeropoulou, Theodora, Prousis, Kyriakos C., Mangani, Stefano, Di Pisa, Flavio, Landi, Giacomo, Iacono, Lucia Dello, Pozzi, Cecilia, Freitas-Junior, Lucio H., dos Santos Pascoalino, Bruno, Bertolacini, Claudia P., Behrens, Birte, Keminer, Oliver, Leu, Jennifer, Wolf, Markus, Reinshagen, Jeanette, Cordeiro-da-Silva, Anabela, Santarem, Nuno, Venturelli, Alberto, Wrigley, Stephen, Karunakaran, Deepa, Kebede, Bethlehem, Pöhner, Ina, Müller, Wolfgang, Panecka-Hofman, Joanna, Wade, Rebecca C., Fenske, Martina, Clos, Joachim, Alunda, José María, Corral, María Jesús, Uliassi, Elisa, Bolognesi, Maria Laura, Linciano, Pasquale, Quotadamo, Antonio, Ferrari, Stefania, Santucci, Matteo, Borsari, Chiara, Costi, Maria Paola, Gul, Sheraz
Publicado 2019