The Rad50 Coiled Coil Domain is indispensable for Mre11 complex functions

por Hohl, Marcel, Kwon, Youngho, Galván, Sandra Muñoz, Xue, Xiaoyu, Tous, Cristina, Aguilera, Andrés, Sung, Patrick, Petrini, John H.J.
Publicado 2011

Domain swapping between FEN-1 and XPG defines regions in XPG that mediate nucleotide excision repair activity and substrate specificity

por Hohl, Marcel, Dunand-Sauthier, Isabelle, Staresincic, Lidija, Jaquier-Gubler, Pascale, Thorel, Fabrizio, Modesti, Mauro, Clarkson, Stuart G., Schärer, Orlando D.
Publicado 2007

Eukaryotic Rad50 Functions as A Rod-shaped Dimer

por Park, Young Bong, Hohl, Marcel, Padjasek, Michał, Jeong, Eunyoung, Jin, Kyeong Sik, Krężel, Artur, Petrini, John H. J., Cho, Yunje
Publicado 2017

RTEL1 influences the abundance and localization of TERRA RNA

por Ghisays, Fiorella, Garzia, Aitor, Wang, Hexiao, Canasto-Chibuque, Claudia, Hohl, Marcel, Savage, Sharon A., Tuschl, Thomas, Petrini, John H. J.
Publicado 2021

Nej1 Interacts with Mre11 to Regulate Tethering and Dna2 Binding at DNA Double-Strand Breaks

por Mojumdar, Aditya, Sorenson, Kyle, Hohl, Marcel, Toulouze, Mathias, Lees-Miller, Susan P., Dubrana, Karine, Petrini, John H.J., Cobb, Jennifer A.
Publicado 2019

The Rad50 hook domain regulates DNA damage signaling and tumorigenesis

por Roset, Ramon, Inagaki, Akiko, Hohl, Marcel, Brenet, Fabienne, Lafrance-Vanasse, Julien, Lange, Julian, Scandura, Joseph M., Tainer, John A., Keeney, Scott, Petrini, John H.J.
Publicado 2014

A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans

por Chansel-Da Cruz, Marie, Hohl, Marcel, Ceppi, Ilaria, Kermasson, Laëtitia, Maggiorella, Laurence, Modesti, Mauro, de Villartay, Jean-Pierre, Ileri, Talia, Cejka, Petr, Petrini, John H.J., Revy, Patrick
Publicado 2020

Modeling cancer genomic data in yeast reveals selection against ATM function during tumorigenesis

por Hohl, Marcel, Mojumdar, Aditya, Hailemariam, Sarem, Kuryavyi, Vitaly, Ghisays, Fiorella, Sorenson, Kyle, Chang, Matthew, Taylor, Barry S., Patel, Dinshaw J., Burgers, Peter M., Cobb, Jennifer A., Petrini, John H. J.
Publicado 2020