Targeting protein geranylgeranylation slows tumor development in a murine model of prostate cancer metastasis

por Reilly, Jacqueline E., Neighbors, Jeffrey D., Hohl, Raymond J.
Publicado 2016

Synthesis of isoprenoid bisphosphonate ethers through C–P bond formations: Potential inhibitors of geranylgeranyl diphosphate synthase

por Zhou, Xiang, Reilly, Jacqueline E, Loerch, Kathleen A, Hohl, Raymond J, Wiemer, David F
Publicado 2014

Prostate cancer in Pennsylvania: The role of older age at diagnosis, aggressiveness, and environmental risk factors on treatment and mortality using data from the Pennsylvania Canc...

por Bluethmann, Shirley M., Wang, Ming, Wasserman, Emily, Chen, Chixiang, Zaorsky, Nicholas G., Hohl, Raymond J., McDonald, Alicia C.
Publicado 2020

Antipsychotic drugs elicit cytotoxicity in glioblastoma multiforme in a calcium‐dependent, non‐D(2) receptor‐dependent, manner

por Weissenrieder, Jillian S., Reed, Jessie L., Moldovan, George‐Lucian, Johnson, Martin T., Trebak, Mohamed, Neighbors, Jeffrey D., Mailman, Richard B., Hohl, Raymond J.
Publicado 2021

RNAseq reveals extensive metabolic disruptions in the sensitive SF-295 cell line treated with schweinfurthins

por Weissenrieder, J. S., Weissenkampen, J. D., Reed, J. L., Green, M. V., Zheng, C., Neighbors, J. D., Liu, D. J., Hohl, Raymond J.
Publicado 2022

A phase I clinical trial of avelumab in combination with decitabine as first line treatment of unfit patients with acute myeloid leukemia

por Zheng, Hong, Mineishi, Shin, Claxton, David, Zhu, Junjia, Zhao, Chenchen, Jia, Bei, Ehmann, W. Christopher, Rybka, Witold B., Naik, Seema, Songdej, Natthapol, Drabick, Joseph J., Hohl, Raymond J.
Publicado 2020

Therapeutic Potential of 5′-Methylschweinfurthin G in Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma

por Koubek, Emily J., Weissenrieder, Jillian S., Ortiz, Luz E., Nwogu, Nnenna, Pham, Alexander M., Weissenkampen, J. Dylan, Reed, Jessie L., Neighbors, Jeffrey D., Hohl, Raymond J., Kwun, Hyun Jin
Publicado 2022

Bone marrow CD8 T cells express high frequency of PD-1 and exhibit reduced anti-leukemia response in newly diagnosed AML patients

por Jia, Bei, Wang, Liru, Claxton, David F., Ehmann, W Christopher, Rybka, Witold B., Mineishi, Shin, Rizvi, Syed, Shike, Hiroko, Bayerl, Michael, Schell, Todd D., Hohl, Raymond J., Zheng, Hong
Publicado 2018

VISTA is highly expressed on MDSCs and mediates an inhibition of T cell response in patients with AML

por Wang, Liru, Jia, Bei, Claxton, David F., Ehmann, W Christopher, Rybka, Witold B., Mineishi, Shin, Naik, Seema, Khawaja, Muhammad R., Sivik, Jeff, Han, Junyan, Hohl, Raymond J., Zheng, Hong
Publicado 2018

GBM-associated mutations and altered protein expression are more common in young patients

por Ferguson, Sherise D., Xiu, Joanne, Weathers, Shiao-Pei, Zhou, Shouhao, Kesari, Santosh, Weiss, Stephanie E., Verhaak, Roeland G., Hohl, Raymond J., Barger, Geoffrey R., Reddy, Sandeep K., Heimberger, Amy B.
Publicado 2016

Blimp-1 impairs T cell function via upregulation of TIGIT and PD-1 in patients with acute myeloid leukemia

por Zhu, Liuluan, Kong, Yaxian, Zhang, Jianhong, Claxton, David F., Ehmann, W. Christopher, Rybka, Witold B., Palmisiano, Neil D., Wang, Ming, Jia, Bei, Bayerl, Michael, Schell, Todd D., Hohl, Raymond J., Zeng, Hui, Zheng, Hong
Publicado 2017

Multi‐dimensional analysis identifies an immune signature predicting response to decitabine treatment in elderly patients with AML

por Zhao, Chenchen, Jia, Bei, Wang, Ming, Schell, Todd D., Claxton, David F., Ehmann, W Christopher, Rybka, Witold B., Mineishi, Shin, Naik, Seema, Songdej, Natthapol, Sivik, Jeff M., Hohl, Raymond J., Zeng, Hui, Zheng, Hong
Publicado 2019

Post-transplant cyclophosphamide alters immune signatures and leads to impaired T cell reconstitution in allogeneic hematopoietic stem cell transplant

por Zhao, Chenchen, Bartock, Matthew, Jia, Bei, Shah, Neal, Claxton, David F., Wirk, Baldeep, Rakszawski, Kevin L., Nickolich, Myles S., Naik, Seema G., Rybka, Witold B., Ehmann, W Christopher C., Hohl, Raymond J., Valentin, Jessica, Bernas-Peterson, Michelle, Gerber, Emily M., Zimmerman, Michele, Mierski, Joseph A., Mineishi, Shin, Zheng, Hong
Publicado 2022

PIGN gene expression aberration is associated with genomic instability and leukemic progression in acute myeloid leukemia with myelodysplastic features

por Teye, Emmanuel K., Sido, Abigail, Xin, Ping, Finnberg, Niklas K., Gokare, Prashanth, Kawasawa, Yuka I., Salzberg, Anna C., Shimko, Sara, Bayerl, Michael, Ehmann, W. Christopher, Claxton, David F., Rybka, Witold B., Drabick, Joseph J., Wang, Hong-Gang, Abraham, Thomas, El-Deiry, Wafik S., Brodsky, Robert A., Hohl, Raymond J., Pu, Jeffrey J.
Publicado 2017