Dysregulated Iron Homeostasis as Common Disease Etiology and Promising Therapeutic Target

por Holbein, Bruce E., Lehmann, Christian
Publicado 2023

Iron Chelator DIBI Suppresses Formation of Ciprofloxacin-Induced Antibiotic Resistance in Staphylococcus aureus

por Allan, David S., Holbein, Bruce E.
Publicado 2022

Comparison of Treatment Effects of Different Iron Chelators in Experimental Models of Sepsis

por Lehmann, Christian, Aali, Maral, Zhou, Juan, Holbein, Bruce
Publicado 2021

Iron Chelation as a Potential Therapeutic Approach in Acute Lung Injury

por Zhang, Xiyang, Zhou, Juan, Holbein, Bruce E., Lehmann, Christian
Publicado 2023

Iron Withdrawal with DIBI, a Novel 3-Hydroxypyridin-4-One Chelator Iron-Binding Polymer, Attenuates Macrophage Inflammatory Responses

por Ghassemi-Rad, Javad, Fernando, Wasundara, Holbein, Bruce E., Hoskin, David W.
Publicado 2023

Antimicrobial Activity of the Iron-Chelator, DIBI, against Multidrug-Resistant Canine Methicillin-Susceptible Staphylococcus pseudintermedius: A Preliminary Study of Four Clinical...

por Nocera, Francesca Paola, Iovane, Giuseppe, De Martino, Luisa, Holbein, Bruce E.
Publicado 2022

Iron-withdrawing anti-infectives for new host-directed therapies based on iron dependence, the Achilles’ heel of antibiotic-resistant microbes

por Holbein, Bruce E., Ang, M. Trisha C., Allan, David S., Chen, Wangxue, Lehmann, Christian
Publicado 2021

Novel Iron-Chelator DIBI Inhibits Staphylococcus aureus Growth, Suppresses Experimental MRSA Infection in Mice and Enhances the Activities of Diverse Antibiotics in vitro

por Parquet, Maria del Carmen, Savage, Kimberley A., Allan, David S., Davidson, Ross J., Holbein, Bruce E.
Publicado 2018

Iron Chelation in Murine Models of Systemic Inflammation Induced by Gram-Positive and Gram-Negative Toxins

por Fokam, Danielle, Dickson, Kayle, Kamali, Kiyana, Holbein, Bruce, Colp, Patricia, Stueck, Ashley, Zhou, Juan, Lehmann, Christian
Publicado 2020

Anti-Inflammatory Effects of the Iron Chelator, DIBI, in Experimental Acute Lung Injury

por Lehmann, Christian, Alizadeh-Tabrizi, Nazli, Hall, Stefan, Faridi, Sufyan, Euodia, Irene, Holbein, Bruce, Zhou, Juan, Chappe, Valerie
Publicado 2022