“Gene accordions” cause genotypic and phenotypic heterogeneity in clonal populations of Staphylococcus aureus

por Belikova, Darya, Jochim, Angelika, Power, Jeffrey, Holden, Matthew T. G., Heilbronner, Simon
Publicado 2020

Naturally occurring polymorphisms in the virulence regulator Rsp modulate Staphylococcus aureus survival in blood and antibiotic susceptibility

por Krishna, Aishwarya, Holden, Matthew T. G., Peacock, Sharon J., Edwards, Andrew M., Wigneshweraraj, Sivaramesh
Publicado 2018

Mapping HPV 16 Sub-Lineages in Anal Cancer and Implications for Disease Outcomes

por Guerendiain, Daniel, Mühr, Laila Sara Arroyo, Grigorescu, Raluca, Holden, Matthew T. G., Cuschieri, Kate
Publicado 2022

Functional analysis of the EsaB component of the Staphylococcus aureus Type VII secretion system

por Casabona, M. Guillermina, Buchanan, Grant, Zoltner, Martin, Harkins, Catriona P., Holden, Matthew T. G., Palmer, Tracy
Publicado 2017

The Emergence of Successful Streptococcus pyogenes Lineages through Convergent Pathways of Capsule Loss and Recombination Directing High Toxin Expression

por Turner, Claire E., Holden, Matthew T. G., Blane, Beth, Horner, Carolyne, Peacock, Sharon J., Sriskandan, Shiranee
Publicado 2019

Origin, maintenance and spread of antibiotic resistance genes within plasmids and chromosomes of bloodstream isolates of Escherichia coli

por Goswami, Cosmika, Fox, Stephen, Holden, Matthew T.G., Connor, Martin, Leanord, Alistair, Evans, Thomas J.
Publicado 2020

The Impact of Recombination on dN/dS within Recently Emerged Bacterial Clones

por Castillo-Ramírez, Santiago, Harris, Simon R., Holden, Matthew T. G., He, Miao, Parkhill, Julian, Bentley, Stephen D., Feil, Edward J.
Publicado 2011

Turner et al. Reply to “Emergence of the Same Successful Clade among Distinct Populations of emm89 Streptococcus pyogenes in Multiple Geographic Regions”

por Turner, Claire E., Lamagni, Theresa, Holden, Matthew T. G., David, Sophia, Jones, Michael D., Game, Laurence, Efstratiou, Androulla, Sriskandan, Shiranee
Publicado 2015

Whole Genome Sequencing and Molecular Epidemiology of Clinical Isolates of Staphylococcus aureus from Algeria

por Namoune, Rachida, Djebbar, Abla, Mekler, Rebecca, McHugh, Martin, Bekara, Mohammed El Amine, Decano, Arun, Holden, Matthew T. G., Sebaihia, Mohammed
Publicado 2023

Genome specialization and decay of the strangles pathogen, Streptococcus equi, is driven by persistent infection

por Harris, Simon R., Robinson, Carl, Steward, Karen F., Webb, Katy S., Paillot, Romain, Parkhill, Julian, Holden, Matthew T.G., Waller, Andrew S.
Publicado 2015

Whole-genome sequencing to investigate a non-clonal melioidosis cluster on a remote Australian island

por Sarovich, Derek S., Chapple, Stephanie N. J., Price, Erin P., Mayo, Mark, Holden, Matthew T. G., Peacock, Sharon J., Currie, Bart J.
Publicado 2017

HPV status and HPV16 viral load in anal cancer and its association with clinical outcome

por Guerendiain, Daniel, Grigorescu, Raluca, Kirk, Anna, Stevenson, Andrew, Holden, Matthew T. G., Pan, Jiafeng, Kavanagh, Kim, Graham, Sheila V., Cuschieri, Kate
Publicado 2022

Microevolution of Burkholderia pseudomallei during an Acute Infection

por Limmathurotsakul, Direk, Holden, Matthew T. G., Coupland, Paul, Price, Erin P., Chantratita, Narisara, Wuthiekanun, Vanaporn, Amornchai, Premjit, Parkhill, Julian, Peacock, Sharon J.
Publicado 2014

Emergence of a New Highly Successful Acapsular Group A Streptococcus Clade of Genotype emm89 in the United Kingdom

por Turner, Claire E., Abbott, James, Lamagni, Theresa, Holden, Matthew T. G., David, Sophia, Jones, Michael D., Game, Laurence, Efstratiou, Androulla, Sriskandan, Shiranee
Publicado 2015

Pan-genomic perspective on the evolution of the Staphylococcus aureus USA300 epidemic

por Jamrozy, Dorota M., Harris, Simon R., Mohamed, Naglaa, Peacock, Sharon J., Tan, Charles Y., Parkhill, Julian, Anderson, Annaliesa S., Holden, Matthew T. G.
Publicado 2016

Haem-iron plays a key role in the regulation of the Ess/type VII secretion system of Staphylococcus aureus RN6390

por Casabona, M. Guillermina, Kneuper, Holger, Alferes de Lima, Daniela, Harkins, Catriona P., Zoltner, Martin, Hjerde, Erik, Holden, Matthew T. G., Palmer, Tracy
Publicado 2017

A novel streptococcal integrative conjugative element involved in iron acquisition

por Heather, Zoe, Holden, Matthew T G, Steward, Karen F, Parkhill, Julian, Song, Lijiang, Challis, Gregory L, Robinson, Carl, Davis-Poynter, Nicholas, Waller, Andrew S
Publicado 2008

Molecular Analysis of an Outbreak of Lethal Postpartum Sepsis Caused by Streptococcus pyogenes

por Turner, Claire E., Dryden, Matthew, Holden, Matthew T. G., Davies, Frances J., Lawrenson, Richard A., Farzaneh, Leili, Bentley, Stephen D., Efstratiou, Androulla, Sriskandan, Shiranee
Publicado 2013

Whole-genome sequencing reveals clonal expansion of multiresistant Staphylococcus haemolyticus in European hospitals

por Cavanagh, Jorunn Pauline, Hjerde, Erik, Holden, Matthew T. G., Kahlke, Tim, Klingenberg, Claus, Flægstad, Trond, Parkhill, Julian, Bentley, Stephen D., Sollid, Johanna U. Ericson
Publicado 2014

The Ess/Type VII secretion system of Staphylococcus aureus shows unexpected genetic diversity

por Warne, Ben, Harkins, Catriona P., Harris, Simon R., Vatsiou, Alexandra, Stanley-Wall, Nicola, Parkhill, Julian, Peacock, Sharon J., Palmer, Tracy, Holden, Matthew T. G.
Publicado 2016