Folded domain charge properties influence the conformational behavior of disordered tails

por Taneja, Ishan, Holehouse, Alex S.
Publicado 2021

PARROT is a flexible recurrent neural network framework for analysis of large protein datasets

por Griffith, Daniel, Holehouse, Alex S
Publicado 2021

Reproducible Analysis of Post-Translational Modifications in Proteomes—Application to Human Mutations

por Holehouse, Alex S., Naegle, Kristen M.
Publicado 2015

Integrating single-molecule spectroscopy and simulations for the study of intrinsically disordered proteins

por Alston, Jhullian J., Soranno, Andrea, Holehouse, Alex S.
Publicado 2021

SHEPHARD: a modular and extensible software architecture for analyzing and annotating large protein datasets

por Ginell, Garrett M, Flynn, Aidan J, Holehouse, Alex S
Publicado 2023

ProteomeScout: a repository and analysis resource for post-translational modifications and proteins

por Matlock, Matthew K., Holehouse, Alex S., Naegle, Kristen M.
Publicado 2014

Sequence determinants of in cell condensate morphology, dynamics, and oligomerization as measured by number and brightness analysis

por Emenecker, Ryan J., Holehouse, Alex S., Strader, Lucia C.
Publicado 2021

Clustering of Aromatic Residues in Prion-like Domains Can Tune the Formation, State, and Organization of Biomolecular Condensates: Published as part of the Biochemistry virtual spe...

por Holehouse, Alex S., Ginell, Garrett M., Griffith, Daniel, Böke, Elvan
Publicado 2021

The analytical Flory random coil is a simple-to-use reference model for unfolded and disordered proteins

por Alston, Jhullian J., Ginell, Garrett M., Soranno, Andrea, Holehouse, Alex S.
Publicado 2023

Sequence-ensemble-function relationships for disordered proteins in live cells

por Holehouse, Alex, Emenecker, Ryan, Guadalupe, Karina, Shamoon, Nora, Sukenik, Shahar
Publicado 2023

Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins

por Harmon, Tyler S, Holehouse, Alex S, Rosen, Michael K, Pappu, Rohit V
Publicado 2017

Investigating the ferric ion binding site of magnetite biomineralisation protein Mms6

por Rawlings, Andrea E., Liravi, Panah, Corbett, Sybilla, Holehouse, Alex S., Staniland, Sarah S.
Publicado 2020

Connecting Coil-to-Globule Transitions to Full Phase Diagrams for Intrinsically Disordered Proteins

por Zeng, Xiangze, Holehouse, Alex S., Chilkoti, Ashutosh, Mittag, Tanja, Pappu, Rohit V.
Publicado 2020

Sequence-ensemble-function relationships for disordered proteins in live cells

por Emenecker, Ryan J., Guadalupe, Karina, Shamoon, Nora M., Sukenik, Shahar, Holehouse, Alex S.
Publicado 2023

Unfolded states under folding conditions accommodate sequence-specific conformational preferences with random coil-like dimensions

por Peran, Ivan, Holehouse, Alex S., Carrico, Isaac S., Pappu, Rohit V., Bilsel, Osman, Raleigh, Daniel P.
Publicado 2019

CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins

por Holehouse, Alex S., Das, Rahul K., Ahad, James N., Richardson, Mary O.G., Pappu, Rohit V.
Publicado 2017

Transcription factor dimerization activates the p300 acetyltransferase

por Ortega, Esther, Rengachari, Srinivasan, Ibrahim, Ziad, Hoghoughi, Naghmeh, Gaucher, Jonathan, Holehouse, Alex S., Khochbin, Saadi, Panne, Daniel
Publicado 2019

Directed mutational scanning reveals a balance between acidic and hydrophobic residues in strong human activation domains

por Staller, Max V., Ramirez, Eddie, Kotha, Sanjana R., Holehouse, Alex S., Pappu, Rohit V., Cohen, Barak A.
Publicado 2022

Combining simulations and single-molecule fluorescence spectroscopy to understand SARS-CoV-2 nucleocapsid protein RNA interaction

por Alston, Jhullian J., Cubuk, Jasmine, Incicco, Jeremias, Stuchell-Brereton, Melissa D., Hall, Kathleen B., Holehouse, Alex S., Soranno, Andrea
Publicado 2023

SWI/SNF senses carbon starvation with a pH-sensitive low-complexity sequence

por Gutierrez, J Ignacio, Brittingham, Gregory P, Karadeniz, Yonca, Tran, Kathleen D, Dutta, Arnob, Holehouse, Alex S, Peterson, Craig L, Holt, Liam J
Publicado 2022