Determining Genetic Causal Variants Through Multivariate Regression Using Mixture Model Penalty

por Sundar, V. S., Fan, Chun-Chieh, Holland, Dominic, Dale, Anders M.
Publicado 2018

Rates of Decline in Alzheimer Disease Decrease with Age

por Holland, Dominic, Desikan, Rahul S., Dale, Anders M., McEvoy, Linda K.
Publicado 2012

Enrichment and Stratification for Predementia Alzheimer Disease Clinical Trials

por Holland, Dominic, McEvoy, Linda K., Desikan, Rahul S., Dale, Anders M.
Publicado 2012

Modifying the minimum criteria for diagnosing amnestic MCI to improve prediction of brain atrophy and progression to Alzheimer’s disease

por Vuoksimaa, Eero, McEvoy, Linda K., Holland, Dominic, Franz, Carol E., Kremen, William S.
Publicado 2018

Insulin-Like Growth Factor Binding Protein 2 Is Associated With Biomarkers of Alzheimer’s Disease Pathology and Shows Differential Expression in Transgenic Mice

por Bonham, Luke W., Geier, Ethan G., Steele, Natasha Z. R., Holland, Dominic, Miller, Bruce L., Dale, Anders M., Desikan, Rahul S., Yokoyama, Jennifer S.
Publicado 2018

An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies

por Thompson, Wesley K., Wang, Yunpeng, Schork, Andrew J., Witoelar, Aree, Zuber, Verena, Xu, Shujing, Werge, Thomas, Holland, Dominic, Andreassen, Ole A., Dale, Anders M.
Publicado 2015

Combining Polygenic Hazard Score With Volumetric MRI and Cognitive Measures Improves Prediction of Progression From Mild Cognitive Impairment to Alzheimer's Disease

por Kauppi, Karolina, Fan, Chun Chieh, McEvoy, Linda K., Holland, Dominic, Tan, Chin Hong, Chen, Chi-Hua, Andreassen, Ole A., Desikan, Rahul S., Dale, Anders M.
Publicado 2018

Beyond SNP heritability: Polygenicity and discoverability of phenotypes estimated with a univariate Gaussian mixture model

por Holland, Dominic, Frei, Oleksandr, Desikan, Rahul, Fan, Chun-Chieh, Shadrin, Alexey A., Smeland, Olav B., Sundar, V. S., Thompson, Paul, Andreassen, Ole A., Dale, Anders M.
Publicado 2020

Characterization and Correction of Geometric Distortions in 814 Diffusion Weighted Images

por Treiber, Jeffrey Mark, White, Nathan S., Steed, Tyler Christian, Bartsch, Hauke, Holland, Dominic, Farid, Nikdokht, McDonald, Carrie R., Carter, Bob S., Dale, Anders Martin, Chen, Clark C.
Publicado 2016

Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics

por Holland, Dominic, Wang, Yunpeng, Thompson, Wesley K., Schork, Andrew, Chen, Chi-Hua, Lo, Min-Tzu, Witoelar, Aree, Werge, Thomas, O'Donovan, Michael, Andreassen, Ole A., Dale, Anders M.
Publicado 2016

Heart fatty acid binding protein and Aβ-associated Alzheimer’s neurodegeneration

por Desikan, Rahul S, Thompson, Wesley K, Holland, Dominic, Hess, Christopher P, Brewer, James B, Zetterberg, Henrik, Blennow, Kaj, Andreassen, Ole A, McEvoy, Linda K, Hyman, Bradley T, Dale, Anders M
Publicado 2013

Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation

por Frei, Oleksandr, Holland, Dominic, Smeland, Olav B., Shadrin, Alexey A., Fan, Chun Chieh, Maeland, Steffen, O’Connell, Kevin S., Wang, Yunpeng, Djurovic, Srdjan, Thompson, Wesley K., Andreassen, Ole A., Dale, Anders M.
Publicado 2019

Phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories revealed by AI-MiXeR

por Shadrin, Alexey A, Frei, Oleksandr, Smeland, Olav B, Bettella, Francesco, O'Connell, Kevin S, Gani, Osman, Bahrami, Shahram, Uggen, Tea K E, Djurovic, Srdjan, Holland, Dominic, Andreassen, Ole A, Dale, Anders M
Publicado 2020

Understanding the genetic determinants of the brain with MOSTest

por van der Meer, Dennis, Frei, Oleksandr, Kaufmann, Tobias, Shadrin, Alexey A., Devor, Anna, Smeland, Olav B., Thompson, Wesley K., Fan, Chun Chieh, Holland, Dominic, Westlye, Lars T., Andreassen, Ole A., Dale, Anders M.
Publicado 2020

Author Correction: Understanding the genetic determinants of the brain with MOSTest

por van der Meer, Dennis, Frei, Oleksandr, Kaufmann, Tobias, Shadrin, Alexey A., Devor, Anna, Smeland, Olav B., Thompson, Wesley K., Fan, Chun Chieh, Holland, Dominic, Westlye, Lars T., Andreassen, Ole A., Dale, Anders M.
Publicado 2020

Leveraging genome characteristics to improve gene discovery for putamen subcortical brain structure

por Chen, Chi-Hua, Wang, Yunpeng, Lo, Min-Tzu, Schork, Andrew, Fan, Chun-Chieh, Holland, Dominic, Kauppi, Karolina, Smeland, Olav B., Djurovic, Srdjan, Sanyal, Nilotpal, Hibar, Derrek P., Thompson, Paul M., Thompson, Wesley K., Andreassen, Ole A., Dale, Anders M.
Publicado 2017

Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS

por Wang, Yunpeng, Thompson, Wesley K., Schork, Andrew J., Holland, Dominic, Chen, Chi-Hua, Bettella, Francesco, Desikan, Rahul S., Li, Wen, Witoelar, Aree, Zuber, Verena, Devor, Anna, Nöthen, Markus M., Rietschel, Marcella, Chen, Qiang, Werge, Thomas, Cichon, Sven, Weinberger, Daniel R., Djurovic, Srdjan, O’Donovan, Michael, Visscher, Peter M., Andreassen, Ole A., Dale, Anders M.
Publicado 2016

The Global ECT-MRI Research Collaboration (GEMRIC): Establishing a multi-site investigation of the neural mechanisms underlying response to electroconvulsive therapy

por Oltedal, Leif, Bartsch, Hauke, Sørhaug, Ole Johan Evjenth, Kessler, Ute, Abbott, Christopher, Dols, Annemieke, Stek, Max L, Ersland, Lars, Emsell, Louise, van Eijndhoven, Philip, Argyelan, Miklos, Tendolkar, Indira, Nordanskog, Pia, Hamilton, Paul, Jorgensen, Martin Balslev, Sommer, Iris E, Heringa, Sophie M, Draganski, Bogdan, Redlich, Ronny, Dannlowski, Udo, Kugel, Harald, Bouckaert, Filip, Sienaert, Pascal, Anand, Amit, Espinoza, Randall, Narr, Katherine L, Holland, Dominic, Dale, Anders M, Oedegaard, Ketil J
Publicado 2017

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score

por Desikan, Rahul S., Fan, Chun Chieh, Wang, Yunpeng, Schork, Andrew J., Cabral, Howard J., Cupples, L. Adrienne, Thompson, Wesley K., Besser, Lilah, Kukull, Walter A., Holland, Dominic, Chen, Chi-Hua, Brewer, James B., Karow, David S., Kauppi, Karolina, Witoelar, Aree, Karch, Celeste M., Bonham, Luke W., Yokoyama, Jennifer S., Rosen, Howard J., Miller, Bruce L., Dillon, William P., Wilson, David M., Hess, Christopher P., Pericak-Vance, Margaret, Haines, Jonathan L., Farrer, Lindsay A., Mayeux, Richard, Hardy, John, Goate, Alison M., Hyman, Bradley T., Schellenberg, Gerard D., McEvoy, Linda K., Andreassen, Ole A., Dale, Anders M.
Publicado 2017

Genetic overlap between Alzheimer’s disease and Parkinson’s disease at the MAPT locus

por Desikan, Rahul S., Schork, Andrew J., Wang, Yunpeng, Witoelar, Aree, Sharma, Manu, McEvoy, Linda K., Holland, Dominic, Brewer, James B., Chen, Chi-Hua, Thompson, Wesley K., Harold, Denise, Williams, Julie, Owen, Michael J., O’Donovan, Michael C., Pericak-Vance, Margaret A., Mayeux, Richard, Haines, Jonathan L., Farrer, Lindsay A., Schellenberg, Gerard D., Heutink, Peter, Singleton, Andrew B., Brice, Alexis, Wood, Nicolas W., Hardy, John, Martinez, Maria, Choi, Seung Hoi, DeStefano, Anita, Ikram, M. Arfan, Bis, Joshua C., Smith, Albert, Fitzpatrick, Annette L., Launer, Lenore, van Duijn, Cornelia, Seshadri, Sudha, Ulstein, Ingun Dina, Aarsland, Dag, Fladby, Tormod, Djurovic, Srdjan, Hyman, Bradley T., Snaedal, Jon, Stefansson, Hreinn, Stefansson, Kari, Gasser, Thomas, Andreassen, Ole A., Dale, Anders M.
Publicado 2015