Strong Heart, Low Ceramides

por Holland, William L., Summers, Scott A.
Publicado 2018

Dichotomous roles of leptin and adiponectin as enforcers against lipotoxicity during feast and famine

por Unger, Roger H., Scherer, Philipp E., Holland, William L.
Publicado 2013

Clinical Trials, Triumphs, and Tribulations of Glucagon Receptor Antagonists

por Pearson, Mackenzie J., Unger, Roger H., Holland, William L.
Publicado 2016

Listen to your heart when ceramide's calling for higher glucose

por Wilkerson, Joseph L., Summers, Scott A., Holland, William L.
Publicado 2019

Low-Density Lipoprotein Receptor-Related Protein-1 Protects Against Hepatic Insulin Resistance and Hepatic Steatosis

por Ding, Yinyuan, Xian, Xunde, Holland, William L., Tsai, Shirling, Herz, Joachim
Publicado 2016

PPARγ-K107 SUMOylation regulates insulin sensitivity but not adiposity in mice

por Katafuchi, Takeshi, Holland, William L., Kollipara, Rahul K., Kittler, Ralf, Mangelsdorf, David J., Kliewer, Steven A.
Publicado 2018

Differential transendothelial transport of adiponectin complexes

por Rutkowski, Joseph M, Halberg, Nils, Wang, Qiong A, Holland, William L, Xia, Jonathan Y, Scherer, Philipp E
Publicado 2014

FOXN3 controls liver glucose metabolism by regulating gluconeogenic substrate selection

por Karanth, Santhosh, Chaurasia, Bhagirath, Bowman, Faith M., Tippetts, Trevor S., Holland, William L., Summers, Scott A., Schlegel, Amnon
Publicado 2019

Senolytic drugs, dasatinib and quercetin, attenuate adipose tissue inflammation, and ameliorate metabolic function in old age

por Islam, Md Torikul, Tuday, Eric, Allen, Shanena, Kim, John, Trott, Daniel W., Holland, William L., Donato, Anthony J., Lesniewski, Lisa A.
Publicado 2023

Brown adipose tissue derived VEGF-A modulates cold tolerance and energy expenditure

por Sun, Kai, Kusminski, Christine M., Luby-Phelps, Kate, Spurgin, Stephen B., An, Yu A., Wang, Qiong A., Holland, William L., Scherer, Philipp E.
Publicado 2014

Ablation of AMP-Activated Protein Kinase α2 Activity Exacerbates Insulin Resistance Induced by High-Fat Feeding of Mice

por Fujii, Nobuharu, Ho, Richard C., Manabe, Yasuko, Jessen, Niels, Toyoda, Taro, Holland, William L., Summers, Scott A., Hirshman, Michael F., Goodyear, Laurie J.
Publicado 2008

Ceramides are necessary and sufficient for diet-induced impairment of thermogenic adipocytes

por Chaurasia, Bhagirath, Ying, Li, Talbot, Chad Lamar, Maschek, John Alan, Cox, James, Schuchman, Edward H., Hirabayashi, Yoshio, Holland, William L., Summers, Scott A.
Publicado 2020

Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration

por Ye, Risheng, Holland, William L, Gordillo, Ruth, Wang, Miao, Wang, Qiong A, Shao, Mengle, Morley, Thomas S, Gupta, Rana K, Stahl, Andreas, Scherer, Philipp E
Publicado 2014

Perilipin 5 links mitochondrial uncoupled respiration in brown fat to healthy white fat remodeling and systemic glucose tolerance

por Gallardo-Montejano, Violeta I., Yang, Chaofeng, Hahner, Lisa, McAfee, John L., Johnson, Joshua A., Holland, William L., Fernandez-Valdivia, Rodrigo, Bickel, Perry E.
Publicado 2021

Directing visceral white adipocyte precursors to a thermogenic adipocyte fate improves insulin sensitivity in obese mice

por Hepler, Chelsea, Shao, Mengle, Xia, Jonathan Y, Ghaben, Alexandra L, Pearson, Mackenzie J, Vishvanath, Lavanya, Sharma, Ankit X, Morley, Thomas S, Holland, William L, Gupta, Rana K
Publicado 2017

Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis

por Holland, William L., Xia, Jonathan Y., Johnson, Joshua A., Sun, Kai, Pearson, Mackenzie J., Sharma, Ankit X., Quittner-Strom, Ezekiel, Tippetts, Trevor S., Gordillo, Ruth, Scherer, Philipp E.
Publicado 2017

Lipidomic QTL in Diversity Outbred mice identifies a novel function for α/β hydrolase domain 2 (Abhd2) as an enzyme that metabolizes phosphatidylcholine and cardiolipin

por Price, Tara R., Stapleton, Donnie S., Schueler, Kathryn L., Norris, Marie K., Parks, Brian W., Yandell, Brian S., Churchill, Gary A., Holland, William L., Keller, Mark P., Attie, Alan D.
Publicado 2023

Lipidomic QTL in Diversity Outbred mice identifies a novel function for α/β hydrolase domain 2 (Abhd2) as an enzyme that metabolizes phosphatidylcholine and cardiolipin

por Price, Tara R., Stapleton, Donnie S., Schueler, Kathryn L., Norris, Marie K., Parks, Brian W., Yandell, Brian S., Churchill, Gary A., Holland, William L., Keller, Mark P., Attie, Alan D.
Publicado 2023

Distinct Regulatory Mechanisms Govern Embryonic versus Adult Adipocyte Maturation

por Wang, Qiong A., Tao, Caroline, Jiang, Lei, Shao, Mengle, Ye, Risheng, Zhu, Yi, Gordillo, Ruth, Ali, Aktar, Lian, Yun, Holland, William L., Gupta, Rana K., Scherer, Philipp E.
Publicado 2015

De novo adipocyte differentiation from Pdgfrβ(+) preadipocytes protects against pathologic visceral adipose expansion in obesity

por Shao, Mengle, Vishvanath, Lavanya, Busbuso, Napoleon C., Hepler, Chelsea, Shan, Bo, Sharma, Ankit X., Chen, Shiuhwei, Yu, Xinxin, An, Yu A., Zhu, Yi, Holland, William L., Gupta, Rana K.
Publicado 2018