Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2

por Plotnik, Joshua P., Hollenhorst, Peter C.
Publicado 2017

Comparison of MAPK specificity across the ETS transcription factor family identifies a high-affinity ERK interaction required for ERG function in prostate cells

por Selvaraj, Nagarathinam, Kedage, Vivekananda, Hollenhorst, Peter C
Publicado 2015

Ras/ERK and PI3K/AKT signaling differentially regulate oncogenic ERG mediated transcription in prostate cells

por Strittmatter, Brady G., Jerde, Travis J., Hollenhorst, Peter C.
Publicado 2021

ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells

por Plotnik, Joshua P., Budka, Justin A., Ferris, Mary W., Hollenhorst, Peter C.
Publicado 2014

Common ELF1 deletion in prostate cancer bolsters oncogenic ETS function, inhibits senescence and promotes docetaxel resistance

por Budka, Justin A., Ferris, Mary W., Capone, Matthew J., Hollenhorst, Peter C.
Publicado 2018

Toll-like receptor 4 signaling activates ERG function in prostate cancer and provides a therapeutic target

por Greulich, Benjamin M, Plotnik, Joshua P, Jerde, Travis J, Hollenhorst, Peter C
Publicado 2021

Androgen signaling connects short isoform production to breakpoint formation at Ewing sarcoma breakpoint region 1

por Nicholas, Taylor R, Metcalf, Stephanie A, Greulich, Benjamin M, Hollenhorst, Peter C
Publicado 2021

Prostate cancer ETS rearrangements switch a cell migration gene expression program from RAS/ERK to PI3K/AKT regulation

por Selvaraj, Nagarathinam, Budka, Justin A, Ferris, Mary W, Jerde, Travis J, Hollenhorst, Peter C
Publicado 2014

­­A high-throughput screen identifies inhibitors of the interaction between the oncogenic transcription factor ERG and the cofactor EWS

por Nicholas, Taylor R., Meng, Jingwei, Greulich, Benjamin M., Morris, Teresa Stevie, Hollenhorst, Peter C.
Publicado 2020

Activation of AKT induces EZH2-mediated β-catenin trimethylation in colorectal cancer

por Ghobashi, Ahmed H., Vuong, Truc T., Kimani, Jane W., Ladaika, Christopher A., Hollenhorst, Peter C., O’Hagan, Heather M.
Publicado 2023

DNA Specificity Determinants Associate with Distinct Transcription Factor Functions

por Hollenhorst, Peter C., Chandler, Katherine J., Poulsen, Rachel L., Johnson, W. Evan, Speck, Nancy A., Graves, Barbara J.
Publicado 2009

Usp9x regulates Ets-1 ubiquitination and stability to control NRAS expression and tumorigenicity in melanoma

por Potu, Harish, Peterson, Luke F., Kandarpa, Malathi, Pal, Anupama, Sun, Hanshi, Durham, Alison, Harms, Paul W., Hollenhorst, Peter C., Eskiocak, Ugur, Talpaz, Moshe, Donato, Nicholas J.
Publicado 2017

Human RNA Polymerase III transcriptomes and relationships to Pol II promoters, enhancer-binding factors and chromatin domains

por Oler, Andrew J., Alla, Ravi K., Roberts, Douglas N., Wong, Alexander, Hollenhorst, Peter C., Chandler, Katherine J., Cassiday, Patrick A., Nelson, Cassie A., Hagedorn, Curt H., Graves, Barbara J., Cairns, Bradley R.
Publicado 2010