Glutamine antagonism attenuates physical and cognitive deficits in a model of MS

por Hollinger, Kristen R., Smith, Matthew D., Kirby, Leslie A., Prchalova, Eva, Alt, Jesse, Rais, Rana, Calabresi, Peter A., Slusher, Barbara S.
Publicado 2019

Glutamine antagonist JHU083 improves psychosocial behavior and sleep deficits in EcoHIV-infected mice

por Bell, Benjamin J., Hollinger, Kristen R., Deme, Pragney, Sakamoto, Shinji, Hasegawa, Yuto, Volsky, David, Kamiya, Atsushi, Haughey, Norman, Zhu, Xiaolei, Slusher, Barbara S.
Publicado 2022

Neutral sphingomyelinase 2 inhibition attenuates extracellular vesicle release and improves neurobehavioral deficits in murine HIV

por Zhu, Xiaolei, Hollinger, Kristen R., Huang, Yiyao, Borjabad, Alejandra, Kim, Boe-Hyun, Arab, Tanina, Thomas, Ajit G., Moniruzzaman, Mohammed, Lovell, Lyndah, Turchinovich, Andrey, Witwer, Kenneth W., Volsky, David J., Haughey, Norman J., Slusher, Barbara S.
Publicado 2022

Dendrimer-2PMPA selectively blocks upregulated microglial GCPII activity and improves cognition in a mouse model of multiple sclerosis

por Hollinger, Kristen R., Sharma, Anjali, Tallon, Carolyn, Lovell, Lyndah, Thomas, Ajit G., Zhu, Xiaolei, Wiseman, Robyn, Wu, Ying, Kambhampati, Siva P., Liaw, Kevin, Sharma, Rishi, Rojas, Camilo, Rais, Rana, Kannan, Sujatha, Kannan, Rangaramanujam M., Slusher, Barbara S.
Publicado 2022

Dendrimer-Conjugated nSMase2 Inhibitor Reduces Tau Propagation in Mice

por Tallon, Carolyn, Bell, Benjamin J., Sharma, Anjali, Pal, Arindom, Malvankar, Medhinee M., Thomas, Ajit G., Yoo, Seung-Wan, Hollinger, Kristen R., Coleman, Kaleem, Wilkinson, Elizabeth L., Kannan, Sujatha, Haughey, Norman J., Kannan, Rangaramanujam M., Rais, Rana, Slusher, Barbara S.
Publicado 2022

Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in murine Alzheimer’s disease

por Tallon, Carolyn, Bell, Benjamin J, Malvankar, Medhinee M, Deme, Pragney, Nogueras-Ortiz, Carlos, Eren, Erden, Thomas, Ajit G, Hollinger, Kristen R, Pal, Arindom, Mustapic, Maja, Huang, Meixiang, Coleman, Kaleem, Joe, Tawnjerae R, Rais, Rana, Haughey, Norman J, Kapogiannis, Dimitrios, Slusher, Barbara S
Publicado 2023

Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in an Alzheimer’s disease mouse model

por Tallon, Carolyn, Bell, Benjamin J., Malvankar, Medhinee M., Deme, Pragney, Nogueras-Ortiz, Carlos, Eren, Erden, Thomas, Ajit G., Hollinger, Kristen R., Pal, Arindom, Mustapic, Maja, Huang, Meixiang, Coleman, Kaleem, Joe, Tawnjerae R., Rais, Rana, Haughey, Norman J., Kapogiannis, Dimitrios, Slusher, Barbara S.
Publicado 2023