ARC (NSC 188491) has identical activity to Sangivamycin (NSC 65346) including inhibition of both P-TEFb and PKC

por Stockwin, Luke H, Yu, Sherry X, Stotler, Howard, Hollingshead, Melinda G, Newton, Dianne L
Publicado 2009

An ELISA system for evaluating antiretroviral activity against Rauscher murine leukemia virus

por Hollingshead, Melinda G., Westbrook, Louise, Ross, Martha J., Bailey, Jean, Qualls, K.Jeanine, Allen, Lois B.
Publicado 1992

Oxyphenisatin acetate (NSC 59687) triggers a cell starvation response leading to autophagy, mitochondrial dysfunction, and autocrine TNFα-mediated apoptosis

por Morrison, Bethanie L, Mullendore, Michael E, Stockwin, Luke H, Borgel, Suzanne, Hollingshead, Melinda G, Newton, Dianne L
Publicado 2013

DNA damage, demethylation and anticancer activity of DNA methyltransferase (DNMT) inhibitors

por Laranjeira, Angelo B. A., Hollingshead, Melinda G., Nguyen, Dat, Kinders, Robert J., Doroshow, James H., Yang, Sherry X.
Publicado 2023

Antitumor Activity of a Novel Oncrasin Analogue Is Mediated by JNK Activation and STAT3 Inhibition

por Guo, Wei, Wu, Shuhong, Wang, Li, Wei, Xiaoli, Liu, Xiaoying, Wang, Ji, Lu, Zhimin, Hollingshead, Melinda, Fang, Bingliang
Publicado 2011

Real-time PCR-based assay to quantify the relative amount of human and mouse tissue present in tumor xenografts

por Alcoser, Sergio Y, Kimmel, David J, Borgel, Suzanne D, Carter, John P, Dougherty, Kelly M, Hollingshead, Melinda G
Publicado 2011

ROADMAPS: An Online Database of Response Data, Dosing Regimens, and Toxicities of Approved Oncology Drugs as Single Agents to Guide Preclinical In Vivo Studies

por Hollingshead, Melinda G., Greenberg, Nathaniel, Gottholm-Ahalt, Michelle, Camalier, Richard, Johnson, Barry C., Collins, Jerry M., Doroshow, James H.
Publicado 2022

Molecular analysis reveals heterogeneity of mouse mammary tumors conditionally mutant for Brca1

por Wright, Mollie H, Robles, Ana I, Herschkowitz, Jason I, Hollingshead, Melinda G, Anver, Miriam R, Perou, Charles M, Varticovski, Lyuba
Publicado 2008

Global Metabolomics Reveals Urinary Biomarkers of Breast Cancer in a MCF-7 Xenograft Mouse Model

por Johnson, Caroline H., Manna, Soumen K., Krausz, Kristopher W., Bonzo, Jessica A., Divelbiss, Raymond D., Hollingshead, Melinda G., Gonzalez, Frank J.
Publicado 2013

A spontaneously metastatic model of bladder cancer: imaging characterization

por Tatum, James L., Kalen, Joseph D., Jacobs, Paula M., Ileva, Lilia V., Riffle, Lisa A., Hollingshead, Melinda G., Doroshow, James H.
Publicado 2019

TET2 and DNMT3A mutations and exceptional response to 4′-thio-2′-deoxycytidine in human solid tumor models

por Yang, Sherry X., Hollingshead, Melinda, Rubinstein, Larry, Nguyen, Dat, Larenjeira, Angelo B. A., Kinders, Robert J., Difilippantonio, Michael, Doroshow, James H.
Publicado 2021

Exploiting embryonic niche conditions to grow Wilms tumor blastema in culture

por Wojcik, Heather M., Lovvorn, Harold N., Hollingshead, Melinda, Pierce, Janene, Stotler, Howard, Murphy, Andrew J., Borgel, Suzanne, Phelps, Hannah M., Correa, Hernan, Perantoni, Alan O.
Publicado 2023

Development of a quantitative pharmacodynamic assay for apoptosis in fixed tumor tissue and its application in distinguishing cytotoxic drug—induced DNA double strand breaks from D...

por Dull, Angie B., Wilsker, Deborah, Hollingshead, Melinda, Mazcko, Christina, Annunziata, Christina M., LeBlanc, Amy K., Doroshow, James H., Kinders, Robert J., Parchment, Ralph E.
Publicado 2018

A Small Molecule (Pluripotin) as a Tool for Studying Cancer Stem Cell Biology: Proof of Concept

por Mertins, Susan D., Scudiero, Dominic A., Hollingshead, Melinda G., Divelbiss, Raymond D., Alley, Michael C., Monks, Anne, Covell, David G., Hite, Karen M., Salomon, David S., Niederhuber, John E.
Publicado 2013

3'-[(18)F]fluoro-3'-deoxythymidine ([(18)F]FLT) Positron Emission Tomography as an In Vivo Biomarker of inhibition of CDK 4/6-Rb pathway by Palbociclib in a patient derived bladder...

por Tatum, James L., Kalen, Joseph D., Jacobs, Paula M., Riffle, Lisa A., James, Amy, Thang, Lai, Sanders, Chelsea, Hollingshead, Melinda G., Basuli, Falguni, Shi, Jianfeng, Doroshow, James H.
Publicado 2022

“Glowing Head” Mice: A Genetic Tool Enabling Reliable Preclinical Image-Based Evaluation of Cancers in Immunocompetent Allografts

por Day, Chi-Ping, Carter, John, Ohler, Zoe Weaver, Bonomi, Carrie, El Meskini, Rajaa, Martin, Philip, Graff-Cherry, Cari, Feigenbaum, Lionel, Tüting, Thomas, Van Dyke, Terry, Hollingshead, Melinda, Merlino, Glenn
Publicado 2014

Dual oxidase 2 and pancreatic adenocarcinoma: IFN-γ-mediated dual oxidase 2 overexpression results in H(2)O(2)-induced, ERK-associated up-regulation of HIF-1α and VEGF-A

por Wu, Yongzhong, Meitzler, Jennifer L., Antony, Smitha, Juhasz, Agnes, Lu, Jiamo, Jiang, Guojian, Liu, Han, Hollingshead, Melinda, Haines, Diana C., Butcher, Donna, Panter, Michaela S., Roy, Krishnendu, Doroshow, James H.
Publicado 2016

Cross-species genomic and functional analyses identify a combination therapy using a CHK1 inhibitor and a ribonucleotide reductase inhibitor to treat triple-negative breast cancer

por Bennett, Christina N, Tomlinson, Christine C, Michalowski, Aleksandra M, Chu, Isabel M, Luger, Dror, Mittereder, Lara R, Aprelikova, Olga, Shou, James, Piwinica-Worms, Helen, Caplen, Natasha J, Hollingshead, Melinda G, Green, Jeffrey E
Publicado 2012

Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay

por Ji, Jiuping, Zhang, Yiping, Redon, Christophe E., Reinhold, William C., Chen, Alice P., Fogli, Laura K., Holbeck, Susan L., Parchment, Ralph E., Hollingshead, Melinda, Tomaszewski, Joseph E., Dudon, Quentin, Pommier, Yves, Doroshow, James H., Bonner, William M.
Publicado 2017

Identification of CBX3 and ABCA5 as Putative Biomarkers for Tumor Stem Cells in Osteosarcoma

por Saini, Vaibhav, Hose, Curtis D., Monks, Anne, Nagashima, Kunio, Han, Bingnan, Newton, Dianne L., Millione, Angelena, Shah, Jalpa, Hollingshead, Melinda G., Hite, Karen M., Burkett, Mark W., Delosh, Rene M., Silvers, Thomas E., Scudiero, Dominic A., Shoemaker, Robert H.
Publicado 2012