Innate and Autoimmunity in the Pathogenesis of Inherited Retinal Dystrophy

por Hollingsworth, T. J., Gross, Alecia K.
Publicado 2020

Activity (transcription) of the genes for MLH1, MSH2 and p53 in sporadic colorectal tumours with micro-satellite instability

por Tou, S I H, Drye, E R, Boulos, P B, Hollingsworth, S J
Publicado 2004

Cellular and Molecular Mechanisms of Pathogenesis Underlying Inherited Retinal Dystrophies

por Manley, Andrew, Meshkat, Bahar I., Jablonski, Monica M., Hollingsworth, T.J.
Publicado 2023

Chronic Proinflammatory Signaling Accelerates the Rate of Degeneration in a Spontaneous Polygenic Model of Inherited Retinal Dystrophy

por Hollingsworth, T. J., Wang, Xiangdi, White, William A., Simpson, Raven N., Jablonski, Monica M.
Publicado 2022

Murine Retinal Citrullination Declines With Age and is Mainly Dependent on Peptidyl Arginine Deiminase 4 (PAD4)

por Hollingsworth, T. J., Radic, Marko Z., Beranova-Giorgianni, Sarka, Giorgianni, Francesco, Wang, Yanming, Iannaccone, Alessandro
Publicado 2018

Enhanced Corneal Penetration of a Poorly Permeable Drug Using Bioadhesive Multiple Microemulsion Technology

por Ibrahim, Mohamed Moustafa, Maria, Doaa Nabih, Wang, XiangDi, Simpson, Raven N., Hollingsworth, T.J., Jablonski, Monica M.
Publicado 2020

The effect of combined expression of interleukin 2 and interleukin 4 on the tumorigenicity and treatment of B16F10 melanoma.

por Hollingsworth, S. J., Darling, D., Gäken, J., Hirst, W., Patel, P., Kuiper, M., Towner, P., Humphreys, S., Farzaneh, F., Mufti, G. J.
Publicado 1996

The National Lung Matrix Trial: translating the biology of stratification in advanced non-small-cell lung cancer

por Middleton, G., Crack, L. R., Popat, S., Swanton, C., Hollingsworth, S. J., Buller, R., Walker, I., Carr, T. H., Wherton, D., Billingham, L. J.
Publicado 2015

Proinflammatory Pathways Are Activated in the Human Q344X Rhodopsin Knock-In Mouse Model of Retinitis Pigmentosa

por Hollingsworth, T.J., Hubbard, Meredith G., Levi, Hailey J., White, William, Wang, Xiangdi, Simpson, Raven, Jablonski, Monica M., Gross, Alecia K.
Publicado 2021

Mechanisms of Acquired Resistance to Savolitinib, a Selective MET Inhibitor in MET-Amplified Gastric Cancer

por Frigault, Melanie M., Markovets, Aleksandra, Nuttall, Barrett, Kim, Kyoung-Mee, Park, Se Hoon, Gangolli, Esha A., Mortimer, Peter G.S., Hollingsworth, Simon J., Hong, Jung Yong, Kim, Kyung, Kim, Seung Tae, Barrett, J. Carl, Lee, Jeeyun
Publicado 2020

Genome-wide association study finds multiple loci associated with intraocular pressure in HS rats

por Fowler, Samuel, Wang, Tengfei, Munro, Daniel, Kumar, Aman, Chitre, Apurva S., Hollingsworth, T. J., Garcia Martinez, Angel, St. Pierre, Celine L., Bimschleger, Hannah, Gao, Jianjun, Cheng, Riyan, Mohammadi, Pejman, Chen, Hao, Palmer, Abraham A., Polesskaya, Oksana, Jablonski, Monica M.
Publicado 2023

Combination of Docetaxel Plus Savolitinib in Refractory Cancer Patients: A Report on Phase I Trial

por Kim, Seung Tae, Lee, Sujin, Park, Minhwa, Park, Se Hoon, Park, Joon Oh, Lim, Ho Yeong, Park, Young Suk, Kang, Won Ki, Gangolli, Esha A., Shin, Hyeongchan, Kim, Kyoung-Mee, Hollingsworth, Simon J., Mortimer, Peter G.S., Lee, Jeeyun
Publicado 2019

Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stre...

por Iannaccone, Alessandro, Giorgianni, Francesco, New, David D., Hollingsworth, T. J., Umfress, Allison, Alhatem, Albert H., Neeli, Indira, Lenchik, Nataliya I., Jennings, Barbara J., Calzada, Jorge I., Satterfield, Suzanne, Mathews, Dennis, Diaz, Rocio I., Harris, Tamara, Johnson, Karen C., Charles, Steve, Kritchevsky, Stephen B., Gerling, Ivan C., Beranova-Giorgianni, Sarka, Radic, Marko Z.
Publicado 2015

Ceralasertib (AZD6738), an Oral ATR Kinase Inhibitor, in Combination with Carboplatin in Patients with Advanced Solid Tumors: A Phase I Study

por Yap, Timothy A., Krebs, Matthew G., Postel-Vinay, Sophie, El-Khouiery, Anthony, Soria, Jean-Charles, Lopez, Juanita, Berges, Alienor, Cheung, S.Y. Amy, Irurzun-Arana, Itziar, Goldwin, Andrew, Felicetti, Brunella, Jones, Gemma N., Lau, Alan, Frewer, Paul, Pierce, Andrew J., Clack, Glen, Stephens, Christine, Smith, Simon A., Dean, Emma, Hollingsworth, Simon J.
Publicado 2021

AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity

por Fok, Jacqueline H. L., Ramos-Montoya, Antonio, Vazquez-Chantada, Mercedes, Wijnhoven, Paul W. G., Follia, Valeria, James, Neil, Farrington, Paul M., Karmokar, Ankur, Willis, Sophie E., Cairns, Jonathan, Nikkilä, Jenni, Beattie, David, Lamont, Gillian M., Finlay, M. Raymond V., Wilson, Joanne, Smith, Aaron, O’Connor, Lenka Oplustil, Ling, Stephanie, Fawell, Stephen E., O’Connor, Mark J., Hollingsworth, Simon J., Dean, Emma, Goldberg, Frederick W., Davies, Barry R., Cadogan, Elaine B.
Publicado 2019