Mitochondrial metabolic remodeling in response to genetic and environmental perturbations

por Hollinshead, Kate E.R., Tennant, Daniel A.
Publicado 2016

Respiratory Supercomplexes Promote Mitochondrial Efficiency and Growth in Severely Hypoxic Pancreatic Cancer

por Hollinshead, Kate E.R., Parker, Seth J., Eapen, Vinay V., Encarnacion-Rosado, Joel, Sohn, Albert, Oncu, Tugba, Cammer, Michael, Mancias, Joseph D., Kimmelman, Alec C.
Publicado 2020

Spontaneous hydrolysis and spurious metabolic properties of α-ketoglutarate esters

por Parker, Seth J., Encarnación-Rosado, Joel, Hollinshead, Kate E. R., Hollinshead, David M., Ash, Leonard J., Rossi, Juan A. K., Lin, Elaine Y., Sohn, Albert S. W., Philips, Mark R., Jones, Drew R., Kimmelman, Alec C.
Publicado 2021

Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism

por Lussey-Lepoutre, Charlotte, Hollinshead, Kate E. R., Ludwig, Christian, Menara, Mélanie, Morin, Aurélie, Castro-Vega, Luis-Jaime, Parker, Seth J., Janin, Maxime, Martinelli, Cosimo, Ottolenghi, Chris, Metallo, Christian, Gimenez-Roqueplo, Anne-Paule, Favier, Judith, Tennant, Daniel A.
Publicado 2015

Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis

por Hollinshead, Kate E.R., Munford, Haydn, Eales, Katherine L., Bardella, Chiara, Li, Chunjie, Escribano-Gonzalez, Cristina, Thakker, Alpesh, Nonnenmacher, Yannic, Kluckova, Katarina, Jeeves, Mark, Murren, Robert, Cuozzo, Federica, Ye, Dan, Laurenti, Giulio, Zhu, Wei, Hiller, Karsten, Hodson, David J., Hua, Wei, Tomlinson, Ian P., Ludwig, Christian, Mao, Ying, Tennant, Daniel A.
Publicado 2018

Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer

por Dowling, Catríona M., Hollinshead, Kate E. R., Di Grande, Alessandra, Pritchard, Justin, Zhang, Hua, Dillon, Eugene T., Haley, Kathryn, Papadopoulos, Eleni, Mehta, Anita K., Bleach, Rachel, Lindner, Andreas U., Mooney, Brian, Düssmann, Heiko, O’Connor, Darran, Prehn, Jochen H. M., Wynne, Kieran, Hemann, Michael, Bradner, James E., Kimmelman, Alec C., Guerriero, Jennifer L., Cagney, Gerard, Wong, Kwok-Kin, Letai, Anthony G., Chonghaile, Tríona Ní
Publicado 2021