The impact of individualised cardiovascular disease (CVD) risk estimates and lifestyle advice on physical activity in individuals at high risk of CVD: a pilot 2 × 2 factorial under...

por Price, Hermione C, Tucker, Lynne, Griffin, Simon J, Holman, Rury R
Publicado 2008

Economic Evaluation of Factorial Trials: Cost-Utility Analysis of the Atorvastatin in Factorial With Omega EE90 Risk Reduction in Diabetes 2 × 2 × 2 Factorial Trial of Atorvastatin...

por Dakin, Helen A., Farmer, Andrew, Gray, Alastair M., Holman, Rury R.
Publicado 2020

Initiating Insulin as Part of the Treating To Target in Type 2 Diabetes (4-T) Trial: An interview study of patients' and health professionals' experiences

por Jenkins, Nicholas, Hallowell, Nina, Farmer, Andrew J., Holman, Rury R., Lawton, Julia
Publicado 2010

Historical HbA(1c) Values May Explain the Type 2 Diabetes Legacy Effect: UKPDS 88

por Lind, Marcus, Imberg, Henrik, Coleman, Ruth L., Nerman, Olle, Holman, Rury R.
Publicado 2021

Health utilities in Chinese patients with coronary heart disease and impaired glucose tolerance (ACE): A longitudinal analysis of a randomized, double‐blind, placebo‐controlled tri...

por Leal, José, Becker, Frauke, Lim, Lee‐Ling, Holman, Rury R., Gray, Alastair M.
Publicado 2022

Temporal Validation of the UKPDS Outcomes Model Using 10-Year Posttrial Monitoring Data

por Leal, Jose, Hayes, Alison J., Gray, Alastair M., Holman, Rury R., Clarke, Philip M.
Publicado 2013

Health selection into neighborhoods among patients enrolled in a clinical trial

por Arcaya, Mariana C., Coleman, Ruth L., Razak, Fahad, Alva, Maria L., Holman, Rury R.
Publicado 2017

Accurately Reflecting Uncertainty When Using Patient-Level Simulation Models to Extrapolate Clinical Trial Data

por Dakin, Helen A., Leal, José, Briggs, Andrew, Clarke, Philip, Holman, Rury R., Gray, Alastair
Publicado 2020

Challenges of maintaining research protocol fidelity in a clinical care setting: A qualitative study of the experiences and views of patients and staff participating in a randomize...

por Lawton, Julia, Jenkins, Nicholas, Darbyshire, Julie L, Holman, Rury R, Farmer , Andrew J, Hallowell, Nina
Publicado 2011

Effect of race on cardiometabolic responses to once-weekly exenatide: insights from the Exenatide Study of Cardiovascular Event Lowering (EXSCEL)

por Davis, Timothy M. E., Giczewska, Anna, Lokhnygina, Yuliya, Mentz, Robert J., Sattar, Naveed, Holman, Rury R.
Publicado 2022

Meta-analysis of the impact of alpha-glucosidase inhibitors on incident diabetes and cardiovascular outcomes

por Coleman, Ruth L., Scott, Charles A. B., Lang, Zhihui, Bethel, M. Angelyn, Tuomilehto, Jaakko, Holman, Rury R.
Publicado 2019

Medical Management of Hyperglycemia in Type 2 Diabetes: A Consensus Algorithm for the Initiation and Adjustment of Therapy: A consensus statement of the American Diabetes Associati...

por Nathan, David M., Buse, John B., Davidson, Mayer B., Ferrannini, Ele, Holman, Rury R., Sherwin, Robert, Zinman, Bernard
Publicado 2009

The effect of a brief action planning intervention on adherence to double-blind study medication compared to a standard trial protocol in the Atorvastatin in Factorial with Omega E...

por Farmer, Andrew J., Oke, Jason, Hardeman, Wendy, Tucker, Lynne, Sutton, Stephen, Kinmonth, Ann-Louise, Griffin, Simon, Holman, Rury R.
Publicado 2016

Risk of Anemia With Metformin Use in Type 2 Diabetes: A MASTERMIND Study

por Donnelly, Louise A., Dennis, John M., Coleman, Ruth L., Sattar, Naveed, Hattersley, Andrew T., Holman, Rury R., Pearson, Ewan R.
Publicado 2020

Performance of the UK Prospective Diabetes Study Risk Engine and the Framingham Risk Equations in Estimating Cardiovascular Disease in the EPIC- Norfolk Cohort

por Simmons, Rebecca K., Coleman, Ruth L., Price, Hermione C., Holman, Rury R., Khaw, Kay-Tee, Wareham, Nicholas J., Griffin, Simon J.
Publicado 2009

Plasma levels of DPP4 activity and sDPP4 are dissociated from inflammation in mice and humans

por Baggio, Laurie L., Varin, Elodie M., Koehler, Jacqueline A., Cao, Xiemin, Lokhnygina, Yuliya, Stevens, Susanna R., Holman, Rury R., Drucker, Daniel J.
Publicado 2020

International Variation in Outcomes Among People with Cardiovascular Disease or Cardiovascular Risk Factors and Impaired Glucose Tolerance: Insights from the NAVIGATOR Trial

por Harumi Higuchi dos Santos, Marilia, Sharma, Abhinav, Sun, Jie‐Lena, Pieper, Karen, McMurray, John J.V., Holman, Rury R., Lopes, Renato D.
Publicado 2017

Relationship between baseline physical activity assessed by pedometer count and new-onset diabetes in the NAVIGATOR trial

por Kraus, William E, Yates, Thomas, Tuomilehto, Jaakko, Sun, Jie-Lena, Thomas, Laine, McMurray, John J V, Bethel, M Angelyn, Holman, Rury R
Publicado 2018

TriMaster: randomised double-blind crossover study of a DPP4 inhibitor, SGLT2 inhibitor and thiazolidinedione as second-line or third-line therapy in patients with type 2 diabetes...

por Angwin, Catherine, Jenkinson, Caroline, Jones, Angus, Jennison, Christopher, Henley, William, Farmer, Andrew, Sattar, Naveed, Holman, Rury R, Pearson, Ewan, Shields, Beverley, Hattersley, Andrew
Publicado 2020

Time-dependent event accumulation in a cardiovascular outcome trial of patients with type 2 diabetes and established atherosclerotic cardiovascular disease

por Bethel, M. Angelyn, Sourij, Harald, Stevens, Susanna R., Hannan, Karen, Lokhnygina, Yuliya, Adler, Amanda I., Peterson, Eric D., Holman, Rury R., Lopes, Renato D.
Publicado 2023