The FusX TALE Base Editor (FusXTBE) for Rapid Mitochondrial DNA Programming of Human Cells In Vitro and Zebrafish Disease Models In Vivo

por Sabharwal, Ankit, Kar, Bibekananda, Restrepo-Castillo, Santiago, Holmberg, Shannon R., Mathew, Neal D., Kendall, Benjamin Luke, Cotter, Ryan P., WareJoncas, Zachary, Seiler, Christoph, Nakamaru-Ogiso, Eiko, Clark, Karl J., Ekker, Stephen C.
Publicado 2021

A Primer Genetic Toolkit for Exploring Mitochondrial Biology and Disease Using Zebrafish

por Sabharwal, Ankit, Campbell, Jarryd M., Schwab, Tanya L., WareJoncas, Zachary, Wishman, Mark D., Ata, Hirotaka, Liu, Wiebin, Ichino, Noriko, Hunter, Danielle E., Bergren, Jake D., Urban, Mark D., Urban, Rhianna M., Holmberg, Shannon R., Kar, Bibekananda, Cook, Alex, Ding, Yonghe, Xu, Xiaolei, Clark, Karl J., Ekker, Stephen C.
Publicado 2022

Genetic therapy in a mitochondrial disease model suggests a critical role for liver dysfunction in mortality

por Sabharwal, Ankit, Wishman, Mark D, Cervera, Roberto Lopez, Serres, MaKayla R, Anderson, Jennifer L, Holmberg, Shannon R, Kar, Bibekananda, Treichel, Anthony J, Ichino, Noriko, Liu, Weibin, Yang, Jingchun, Ding, Yonghe, Deng, Yun, Lacey, Jean M, Laxen, William J, Loken, Perry R, Oglesbee, Devin, Farber, Steven A, Clark, Karl J, Xu, Xiaolei, Ekker, Stephen C
Publicado 2022