Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis

por Maio, Nunziata, Kim, Ki Soon, Holmes-Hampton, Gregory, Singh, Anamika, Rouault, Tracey A.
Publicado 2019

Impairment of IGF-1 Signaling and Antioxidant Response Are Associated with Radiation Sensitivity and Mortality

por Y. Aghdam, Saeed, Kenchegowda, Doreswamy, Holmes-Hampton, Gregory P., Moroni, Maria, P. Ghosh, Sanchita
Publicado 2021

PrC-210 Protects against Radiation-Induced Hematopoietic and Intestinal Injury in Mice and Reduces Oxidative Stress

por Kumar, Vidya P., Biswas, Shukla, Holmes-Hampton, Gregory P., Goesch, Torsten, Fahl, William, Ghosh, Sanchita P.
Publicado 2023

CDX-301: a novel medical countermeasure for hematopoietic acute radiation syndrome in mice

por Satyamitra, Merriline, Cary, Lynnette, Dunn, Dylan, Holmes-Hampton, Gregory P., Thomas, Lawrence J., Ghosh, Sanchita P.
Publicado 2020

Dysregulated Cardiac IGF-1 Signaling and Antioxidant Response Are Associated with Radiation Sensitivity

por Aghdam, Saeed Y., Kenchegowda, Doreswamy, Sharma, Neel K., Holmes-Hampton, Gregory P., Legesse, Betre, Moroni, Maria, Ghosh, Sanchita P.
Publicado 2020

Pre-Administration of PLX-R18 Cells Protects Mice from Radiation-Induced Hematopoietic Failure and Lethality

por Kumar, Vidya P., Biswas, Shukla, Holmes-Hampton, Gregory P., Sheleg, Michal, Stone, Sasha, Legesse, Betre, Ofir, Racheli, Ghosh, Sanchita P.
Publicado 2022

Early to sustained impacts of lethal radiation on circulating miRNAs in a minipig model

por Chakraborty, Nabarun, Holmes-Hampton, Gregory P., Gautam, Aarti, Kumar, Raina, Hritzo, Bernadette, Legesse, Betre, Dimitrov, George, Ghosh, Sanchita P., Hammamieh, Rasha
Publicado 2023

CDX-301 prevents radiation-induced dysregulation of miRNA expression and biogenesis

por Soni, Dharmendra Kumar, Kumar, Vidya P., Biswas, Shukla, Holmes-Hampton, Gregory P., Bhattacharyya, Sharmistha, Thomas, Lawrence J., Biswas, Roopa, Ghosh, Sanchita P.
Publicado 2022

PEGylated thrombopoietin mimetic, JNJ‑26366821 a novel prophylactic radiation countermeasure for acute radiation injury

por Holmes-Hampton, Gregory P., Kumar, Vidya P., Biswas, Shukla, Stone, Sasha, Sharma, Neel K., Legesse, Betre, Vercellino, Justin, Guha, Chandan, Eichenbaum, Gary, Ghosh, Sanchita P.
Publicado 2023

Mitigation of total body irradiation-induced mortality and hematopoietic injury of mice by a thrombopoietin mimetic (JNJ-26366821)

por Kumar, Vidya P., Holmes-Hampton, Gregory P., Biswas, Shukla, Stone, Sasha, Sharma, Neel Kamal, Hritzo, Bernadette, Guilfoyle, Mary, Eichenbaum, Gary, Guha, Chandan, Ghosh, Sanchita P.
Publicado 2022

Mitochondrial Degeneration and Autophagy Associated With Delayed Effects of Radiation in the Mouse Brain

por Sharma, Neel K., Stone, Sasha, Kumar, Vidya P., Biswas, Shukla, Aghdam, Saeed Y., Holmes-Hampton, Gregory P., Fam, Christine M., Cox, George N., Ghosh, Sanchita P.
Publicado 2019

microRNA and Metabolite Signatures Linked to Early Consequences of Lethal Radiation

por Chakraborty, Nabarun, Gautam, Aarti, Holmes-Hampton, Gregory P., Kumar, Vidya P., Biswas, Shukla, Kumar, Raina, Hamad, Dana, Dimitrov, George, Olabisi, Ayodele O., Hammamieh, Rasha, Ghosh, Sanchita P.
Publicado 2020

Delayed effects of acute whole body lethal radiation exposure in mice pre-treated with BBT-059

por Sharma, Neel K., Holmes-Hampton, Gregory P., Kumar, Vidya P., Biswas, Shukla, Wuddie, Kefale, Stone, Sasha, Aschenake, Zemenu, Wilkins, William L., Fam, Christine M., Cox, George N., Ghosh, Sanchita P.
Publicado 2020

Late Health Effects of Partial Body Irradiation Injury in a Minipig Model Are Associated with Changes in Systemic and Cardiac IGF-1 Signaling

por Hritzo, Bernadette, Aghdam, Saeed Y., Legesse, Betre, Kaur, Amandeep, Cao, Maohua, Boerma, Marjan, Chakraborty, Nabarun, Dimitrov, George, Gautam, Aarti, Hammamieh, Rasha, Wilkins, William, Tsioplaya, Alena, Holmes-Hampton, Gregory P., Moroni, Maria
Publicado 2021