Systematic review of antitumour efficacy and mechanism of metformin activity in prostate cancer models

por Wang, Nan Fang, Jue, Toni Rose, Holst, Jeff, Gunter, Jennifer H.
Publicado 2022

Luciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivo

por Tiffen, Jessamy C, Bailey, Charles G, Ng, Cynthia, Rasko, John EJ, Holst, Jeff
Publicado 2010

TP53 Mutation Is a Prognostic Factor in Lower Grade Glioma and May Influence Chemotherapy Efficacy

por Noor, Humaira, Briggs, Nancy E., McDonald, Kerrie L., Holst, Jeff, Vittorio, Orazio
Publicado 2021

Homology Modeling Informs Ligand Discovery for the Glutamine Transporter ASCT2

por Garibsingh, Rachel-Ann A., Otte, Nicholas J., Ndaru, Elias, Colas, Claire, Grewer, Christof, Holst, Jeff, Schlessinger, Avner
Publicado 2018

EGF-activated PI3K/Akt signalling coordinates leucine uptake by regulating LAT3 expression in prostate cancer

por Zhang, Blake K., Moran, Anne M., Bailey, Charles G., Rasko, John E. J., Holst, Jeff, Wang, Qian
Publicado 2019

From signalling pathways to targeted therapies: unravelling glioblastoma’s secrets and harnessing two decades of progress

por Dewdney, Brittany, Jenkins, Misty R., Best, Sarah A., Freytag, Saskia, Prasad, Krishneel, Holst, Jeff, Endersby, Raelene, Johns, Terrance G.
Publicado 2023

Ligand Discovery for the Alanine-Serine-Cysteine Transporter (ASCT2, SLC1A5) from Homology Modeling and Virtual Screening

por Colas, Claire, Grewer, Christof, Otte, Nicholas James, Gameiro, Armanda, Albers, Thomas, Singh, Kurnvir, Shere, Helen, Bonomi, Massimiliano, Holst, Jeff, Schlessinger, Avner
Publicado 2015

Identifying microRNA determinants of human myelopoiesis

por Rajasekhar, Megha, Schmitz, Ulf, Flamant, Stephane, Wong, Justin J.-L., Bailey, Charles G., Ritchie, William, Holst, Jeff, Rasko, John E. J.
Publicado 2018

Identification of nuclear-enriched miRNAs during mouse granulopoiesis

por Wong, Justin JL, Ritchie, William, Gao, Dadi, Lau, Katherine A, Gonzalez, Maria, Choudhary, Anupma, Taft, Ryan J, Rasko, John EJ, Holst, Jeff
Publicado 2014

The antiproliferative ELF2 isoform, ELF2B, induces apoptosis in vitro and perturbs early lymphocytic development in vivo

por Guan, Fiona H. X., Bailey, Charles G., Metierre, Cynthia, O’Young, Patrick, Gao, Dadi, Khoo, Teh Liane, Holst, Jeff, Rasko, John E. J.
Publicado 2017

Inhibition of glutamine uptake regulates mTORC1, glutamine metabolism and cell growth in prostate cancer

por Wang, Qian, Hardie, Rae-Anne, Balaban, Seher, Schreuder, Mark, Hoy, Andrew, van Geldermalsen, Michelle, Fazli, Ladan, Nagarajah, Rajini, Bailey, Charles, Rasko, John, Holst, Jeff
Publicado 2014

Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways

por van Geldermalsen, Michelle, Quek, Lake-Ee, Turner, Nigel, Freidman, Natasha, Pang, Angel, Guan, Yi Fang, Krycer, James R., Ryan, Renae, Wang, Qian, Holst, Jeff
Publicado 2018

Targeting of cytosolic phospholipase A(2)α impedes cell cycle re-entry of quiescent prostate cancer cells

por Yao, Mu, Xie, Chanlu, Kiang, Mei-Yee, Teng, Ying, Harman, David, Tiffen, Jessamy, Wang, Qian, Sved, Paul, Bao, Shisan, Witting, Paul, Holst, Jeff, Dong, Qihan
Publicado 2015

Androgen receptor and nutrient signaling pathways coordinate increased amino acid transport in prostate cancer progression

por Wang, Qian, Bailey, Charles G, Ng, Cynthia, Tiffen, Jessamy, Thoeng, Annora, Minnas, Vineet, Lehman, Melanie L, Hendy, Stephen C, Buchanan, Grant, Nelson, Colleen C, Rasko, John EJ, Holst, Jeff
Publicado 2012

Monoterpene Glycoside ESK246 from Pittosporum Targets LAT3 Amino Acid Transport and Prostate Cancer Cell Growth

por Wang, Qian, Grkovic, Tanja, Font, Josep, Bonham, Sarah, Pouwer, Rebecca H, Bailey, Charles G, Moran, Anne M, Ryan, Renae M, Rasko, John EJ, Jormakka, Mika, Quinn, Ronald J, Holst, Jeff
Publicado 2014

Intron retention is regulated by altered MeCP2-mediated splicing factor recruitment

por Wong, Justin J. -L., Gao, Dadi, Nguyen, Trung V., Kwok, Chau-To, van Geldermalsen, Michelle, Middleton, Rob, Pinello, Natalia, Thoeng, Annora, Nagarajah, Rajini, Holst, Jeff, Ritchie, William, Rasko, John E. J.
Publicado 2017

Glutamine addiction promotes glucose oxidation in triple-negative breast cancer

por Quek, Lake-Ee, van Geldermalsen, Michelle, Guan, Yi Fang, Wahi, Kanu, Mayoh, Chelsea, Balaban, Seher, Pang, Angel, Wang, Qian, Cowley, Mark J., Brown, Kristin K., Turner, Nigel, Hoy, Andrew J., Holst, Jeff
Publicado 2022

Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration

por Balaban, Seher, Shearer, Robert F., Lee, Lisa S., van Geldermalsen, Michelle, Schreuder, Mark, Shtein, Harrison C., Cairns, Rose, Thomas, Kristen C., Fazakerley, Daniel J., Grewal, Thomas, Holst, Jeff, Saunders, Darren N., Hoy, Andrew J.
Publicado 2017

RBM3 regulates temperature sensitive miR-142–5p and miR-143 (thermomiRs), which target immune genes and control fever

por Wong, Justin J.-L., Au, Amy Y.M., Gao, Dadi, Pinello, Natalia, Kwok, Chau-To, Thoeng, Annora, Lau, Katherine A., Gordon, Jane E.A., Schmitz, Ulf, Feng, Yue, Nguyen, Trung V., Middleton, Robert, Bailey, Charles G., Holst, Jeff, Rasko, John E.J., Ritchie, William
Publicado 2016

A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth

por Gillis, Joanna L, Hinneh, Josephine A, Ryan, Natalie K, Irani, Swati, Moldovan, Max, Quek, Lake-Ee, Shrestha, Raj K, Hanson, Adrienne R, Xie, Jianling, Hoy, Andrew J, Holst, Jeff, Centenera, Margaret M, Mills, Ian G, Lynn, David J, Selth, Luke A, Butler, Lisa M
Publicado 2021