The discrepancy between chromatin factor location and effect

por Lenstra, Tineke L., Holstege, Frank C.P.
Publicado 2012

Multifunctional genes

por van de Peppel, Jeroen, Holstege, Frank C P
Publicado 2005

Growth condition dependency is the major cause of non-responsiveness upon genetic perturbation

por Amini, Saman, Holstege, Frank C. P., Kemmeren, Patrick
Publicado 2017

An Optimized Chromatin Immunoprecipitation Protocol for Quantification of Protein-DNA Interactions

por de Jonge, Wim J., Brok, Mariël, Kemmeren, Patrick, Holstege, Frank C.P.
Publicado 2020

CHETAH: a selective, hierarchical cell type identification method for single-cell RNA sequencing

por de Kanter, Jurrian K, Lijnzaad, Philip, Candelli, Tito, Margaritis, Thanasis, Holstege, Frank C P
Publicado 2019

Ewing Sarcoma Single-cell Transcriptome Analysis Reveals Functionally Impaired Antigen-presenting Cells

por Visser, Lindy L., Bleijs, Margit, Margaritis, Thanasis, van de Wetering, Marc, Holstege, Frank C. P., Clevers, Hans
Publicado 2023

E2F7 represses a network of oscillating cell cycle genes to control S-phase progression

por Westendorp, Bart, Mokry, Michal, Groot Koerkamp, Marian J.A., Holstege, Frank C.P., Cuppen, Edwin, de Bruin, Alain
Publicado 2012

High-Throughput Genetic and Gene Expression Analysis of the RNAPII-CTD Reveals Unexpected Connections to SRB10/CDK8

por Aristizabal, Maria J., Negri, Gian Luca, Benschop, Joris J., Holstege, Frank C. P., Krogan, Nevan J., Kobor, Michael S.
Publicado 2013

Suppression of intragenic transcription requires the MOT1 and NC2 regulators of TATA-binding protein

por Koster, Maria J. E., Yildirim, Asli D., Weil, P. Anthony, Holstege, Frank C. P., Timmers, H. Th. Marc
Publicado 2014

A novel role for Sem1 and TREX-2 in transcription involves their impact on recruitment and H2B deubiquitylation activity of SAGA

por García-Oliver, Encar, Pascual-García, Pau, García-Molinero, Varinia, Lenstra, Tineke L., Holstege, Frank C. P., Rodríguez-Navarro, Susana
Publicado 2013

The ability of transcription factors to differentially regulate gene expression is a crucial component of the mechanism underlying inversion, a frequently observed genetic interact...

por Amini, Saman, Jacobsen, Annika, Ivanova, Olga, Lijnzaad, Philip, Heringa, Jaap, Holstege, Frank C. P., Feenstra, K. Anton, Kemmeren, Patrick
Publicado 2019

Amygdala 14-3-3ζ as a Novel Modulator of Escalating Alcohol Intake in Mice

por Lesscher, Heidi M. B., Houthuijzen, Julia M., Groot Koerkamp, Marian J., Holstege, Frank C. P., Vanderschuren, Louk J. M. J.
Publicado 2012

Improved genome-wide localization by ChIP-chip using double-round T7 RNA polymerase-based amplification

por van Bakel, Harm, van Werven, Folkert J., Radonjic, Marijana, Brok, Mariel O., van Leenen, Dik, Holstege, Frank C. P., Timmers, H. T. Marc
Publicado 2008

A systematic analysis of genetic interactions and their underlying biology in childhood cancer

por Daub, Josephine T., Amini, Saman, Kersjes, Denise J. E., Ma, Xiaotu, Jäger, Natalie, Zhang, Jinghui, Pfister, Stefan M., Holstege, Frank C. P., Kemmeren, Patrick
Publicado 2021

A Barcode Screen for Epigenetic Regulators Reveals a Role for the NuB4/HAT-B Histone Acetyltransferase Complex in Histone Turnover

por Verzijlbergen, Kitty F., van Welsem, Tibor, Sie, Daoud, Lenstra, Tineke L., Turner, Daniel J., Holstege, Frank C. P., Kerkhoven, Ron M., van Leeuwen, Fred
Publicado 2011

Genome wide expression profiling of the mesodiencephalic region identifies novel factors involved in early and late dopaminergic development

por Chakrabarty, Koushik, Von Oerthel, Lars, Hellemons, Anita, Clotman, Frédéric, Espana, Agnès, Groot Koerkamp, Marian, Holstege, Frank C. P., Pasterkamp, R. Jeroen, Smidt, Marten P.
Publicado 2012

Recruitment of TREX to the Transcription Machinery by Its Direct Binding to the Phospho-CTD of RNA Polymerase II

por Meinel, Dominik M., Burkert-Kautzsch, Cornelia, Kieser, Anja, O'Duibhir, Eoghan, Siebert, Matthias, Mayer, Andreas, Cramer, Patrick, Söding, Johannes, Holstege, Frank C. P., Sträßer, Katja
Publicado 2013

The Role of Ctk1 Kinase in Termination of Small Non-Coding RNAs

por Lenstra, Tineke L., Tudek, Agnieszka, Clauder, Sandra, Xu, Zhenyu, Pachis, Spyridon T., van Leenen, Dik, Kemmeren, Patrick, Steinmetz, Lars M., Libri, Domenico, Holstege, Frank C. P.
Publicado 2013

Identification and characterization of relapse-initiating cells in MLL-rearranged infant ALL by single-cell transcriptomics

por Candelli, Tito, Schneider, Pauline, Garrido Castro, Patricia, Jones, Luke A., Bodewes, Eduard, Rockx-Brouwer, Dedeke, Pieters, Rob, Holstege, Frank C. P., Margaritis, Thanasis, Stam, Ronald W.
Publicado 2021

Caenorhabditis elegans Cyclin D/CDK4 and Cyclin E/CDK2 Induce Distinct Cell Cycle Re-Entry Programs in Differentiated Muscle Cells

por Korzelius, Jerome, The, Inge, Ruijtenberg, Suzan, Prinsen, Martine B. W., Portegijs, Vincent, Middelkoop, Teije C., Groot Koerkamp, Marian J., Holstege, Frank C. P., Boxem, Mike, van den Heuvel, Sander
Publicado 2011