Optimized Administration of the M(4) PAM VU0467154 Demonstrates Broad Efficacy, but Limited Effective Concentrations in Mecp2(+/–) Mice

por Cikowski, Jakub, Holt, Calista, Arthur, Bright, Smith, Mackenzie, Gonzalez, Sonia, Lindsley, Craig W., Niswender, Colleen M., Gogliotti, Rocco G.
Publicado 2022

Clinical and Preclinical Evidence for M(1) Muscarinic Acetylcholine Receptor Potentiation as a Therapeutic Approach for Rett Syndrome

por Smith, Mackenzie, Arthur, Bright, Cikowski, Jakub, Holt, Calista, Gonzalez, Sonia, Fisher, Nicole M., Vermudez, Sheryl Anne D., Lindsley, Craig W., Niswender, Colleen M., Gogliotti, Rocco G.
Publicado 2022