Molecular earplugs to protect the inner ear

por Chaves, Mary G., Holt, Jeffrey R.
Publicado 2023

Functional contributions of HCN channels in the primary auditory neurons of the mouse inner ear

por Kim, Ye-Hyun, Holt, Jeffrey R.
Publicado 2013

Split otoferlins reunited

por Holt, Jeffrey R, Geleoc, Gwenaelle SG
Publicado 2018

International Conference on Coding Theory and Quantum Computing

por Evans, David, Holt, Jeffrey J, Jones, Chris
Publicado 2005

Gene therapy for carcinoma of the breast: Therapeutic genetic correction strategies

por Obermiller, Patrice S, Tait, David L, Holt, Jeffrey T
Publicado 2000

Mechanotransduction and hyperpolarization-activated currents contribute to spontaneous activity in mouse vestibular ganglion neurons

por Horwitz, Geoffrey C., Risner-Janiczek, Jessica R., Holt, Jeffrey R.
Publicado 2014

Sensory transduction is required for normal development and maturation of cochlear inner hair cell synapses

por Lee, John, Kawai, Kosuke, Holt, Jeffrey R, Géléoc, Gwenaëlle SG
Publicado 2021

HCN Channels Are Not Required for Mechanotransduction in Sensory Hair Cells of the Mouse Inner Ear

por Horwitz, Geoffrey C., Lelli, Andrea, Géléoc, Gwenaëlle S. G., Holt, Jeffrey R.
Publicado 2010

Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells

por Liu, Xiao-Ping, Koehler, Karl R., Mikosz, Andrew M., Hashino, Eri, Holt, Jeffrey R.
Publicado 2016

Neonatal AAV gene therapy rescues hearing in a mouse model of SYNE4 deafness

por Taiber, Shahar, Cohen, Roie, Yizhar‐Barnea, Ofer, Sprinzak, David, Holt, Jeffrey R, Avraham, Karen B
Publicado 2020

Regenerating hair cells in vestibular sensory epithelia from humans

por Taylor, Ruth Rebecca, Filia, Anastasia, Paredes, Ursula, Asai, Yukako, Holt, Jeffrey R, Lovett, Michael, Forge, Andrew
Publicado 2018

Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss

por Shubina-Oleinik, Olga, Nist-Lund, Carl, French, Courtney, Rockowitz, Shira, Shearer, A. Eliot, Holt, Jeffrey R.
Publicado 2021

Optimized AAV Vectors for TMC1 Gene Therapy in a Humanized Mouse Model of DFNB7/11

por Marcovich, Irina, Baer, Nicholas K., Shubina-Oleinik, Olga, Eclov, Rachel, Beard, Clayton W., Holt, Jeffrey R.
Publicado 2022

A Gata3–Mafb transcriptional network directs post-synaptic differentiation in synapses specialized for hearing

por Yu, Wei-Ming, Appler, Jessica M, Kim, Ye-Hyun, Nishitani, Allison M, Holt, Jeffrey R, Goodrich, Lisa V
Publicado 2013

Generation of inner ear organoids with functional hair cells from human pluripotent stem cells

por Koehler, Karl R., Nie, Jing, Longworth-Mills, Emma, Liu, Xiao-Ping, Lee, Jiyoon, Holt, Jeffrey R., Hashino, Eri
Publicado 2017

Tmc2 expression partially restores auditory function in a mouse model of DFNB7/B11 deafness caused by loss of Tmc1 function

por Nakanishi, Hiroshi, Kurima, Kiyoto, Pan, Bifeng, Wangemann, Philine, Fitzgerald, Tracy S., Géléoc, Gwenaëlle S., Holt, Jeffrey R., Griffith, Andrew J.
Publicado 2018

Differentiation of neurons from neural precursors generated in floating spheres from embryonic stem cells

por Li, Huawei, Liu, Hong, Corrales, C Eduardo, Risner, Jessica R, Forrester, Jeff, Holt, Jeffrey R, Heller, Stefan, Edge, Albert SB
Publicado 2009

Single and Dual Vector Gene Therapy with AAV9-PHP.B Rescues Hearing in Tmc1 Mutant Mice

por Wu, Jason, Solanes, Paola, Nist-Lund, Carl, Spataro, Sofia, Shubina-Oleinik, Olga, Marcovich, Irina, Goldberg, Hannah, Schneider, Bernard L., Holt, Jeffrey R.
Publicado 2021

RNA Interference Prevents Autosomal-Dominant Hearing Loss

por Shibata, Seiji B., Ranum, Paul T., Moteki, Hideaki, Pan, Bifeng, Goodwin, Alexander T., Goodman, Shawn S., Abbas, Paul J., Holt, Jeffrey R., Smith, Richard J.H.
Publicado 2016

A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear

por Landegger, Lukas D., Pan, Bifeng, Askew, Charles, Wassmer, Sarah, Gluck, Sarah, Galvin, Alice, Taylor, Ruth, Forge, Andrew, Stankovic, Konstantina M., Holt, Jeffrey R., Vandenberghe, Luk H.
Publicado 2017