Increased mesoscale diffusivity in response to acute glucose starvation

por Xie, Ying, Gresham, David, Holt, Liam
Publicado 2023

Increased mesoscale diffusivity in response to acute glucose starvation

por Xie, Ying, Gresham, David, Holt, Liam J
Publicado 2023

mRNA condensation fluidizes the cytoplasm

por Xie, Ying, Liu, Tiewei, Gresham, David, Holt, Liam J
Publicado 2023

Synthetic-Evolution Reveals Narrow Paths to Regulation of the Saccharomyces cerevisiae Mitotic Kinesin-5 Cin8

por Goldstein, Alina, Goldman, Darya, Valk, Ervin, Loog, Mart, Holt, Liam J., Gheber, Larisa
Publicado 2019

Control of nuclear size by osmotic forces in Schizosaccharomyces pombe

por Lemière, Joël, Real-Calderon, Paula, Holt, Liam J, Fai, Thomas G, Chang, Fred
Publicado 2022

Condensation of LINE-1 is critical for retrotransposition

por Sil, Srinjoy, Keegan, Sarah, Ettefa, Farida, Denes, Lance T, Boeke, Jef D, Holt, Liam J
Publicado 2023

Condensed-phase signaling can expand kinase specificity and respond to macromolecular crowding

por Sang, Dajun, Shu, Tong, Pantoja, Christian F., de Opakua, Alain Ibáñez, Zweckstetter, Markus, Holt, Liam J.
Publicado 2022

The environmental stress response regulates ribosome content in cell cycle-arrested S. cerevisiae

por Terhorst, Allegra, Sandikci, Arzu, Whittaker, Charles A., Szórádi, Tamás, Holt, Liam J., Neurohr, Gabriel E., Amon, Angelika
Publicado 2023

Mesoscale molecular assembly is favored by the active, crowded cytoplasm

por Shu, Tong, Mitra, Gaurav, Alberts, Jonathan, Viana, Matheus P., Levy, Emmanuel D., Hocky, Glen M., Holt, Liam J.
Publicado 2023

Spatial heterogeneity of the cytosol revealed by machine learning-based 3D particle tracking

por McLaughlin, Grace A., Langdon, Erin M., Crutchley, John M., Holt, Liam J., Forest, M. Gregory, Newby, Jay M., Gladfelter, Amy S.
Publicado 2020

SWI/SNF senses carbon starvation with a pH-sensitive low-complexity sequence

por Gutierrez, J Ignacio, Brittingham, Gregory P, Karadeniz, Yonca, Tran, Kathleen D, Dutta, Arnob, Holehouse, Alex S, Peterson, Craig L, Holt, Liam J
Publicado 2022

A glucose-starvation response regulates the diffusion of macromolecules

por Joyner, Ryan P, Tang, Jeffrey H, Helenius, Jonne, Dultz, Elisa, Brune, Christiane, Holt, Liam J, Huet, Sebastien, Müller, Daniel J, Weis, Karsten
Publicado 2016

Chromosome clustering by Ki-67 excludes cytoplasm during nuclear assembly

por Cuylen-Haering, Sara, Petrovic, Mina, Hernandez-Armendariz, Alberto, Schneider, Maximilian W. G., Samwer, Matthias, Blaukopf, Claudia, Holt, Liam J., Gerlich, Daniel W.
Publicado 2020

Ancestral resurrection reveals evolutionary mechanisms of kinase plasticity

por Howard, Conor J, Hanson-Smith, Victor, Kennedy, Kristopher J, Miller, Chad J, Lou, Hua Jane, Johnson, Alexander D, Turk, Benjamin E, Holt, Liam J
Publicado 2014

CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function

por Canning, Peter, Park, Kwangjin, Gonçalves, João, Li, Chunmei, Howard, Conor J., Sharpe, Timothy D., Holt, Liam J., Pelletier, Laurence, Bullock, Alex N., Leroux, Michel R.
Publicado 2018

Ancestral reconstruction reveals mechanisms of ERK regulatory evolution

por Sang, Dajun, Pinglay, Sudarshan, Wiewiora, Rafal P, Selvan, Myvizhi E, Lou, Hua Jane, Chodera, John D, Turk, Benjamin E, Gümüş, Zeynep H, Holt, Liam J
Publicado 2019

Comprehensive Scanning Mutagenesis of Human Retrotransposon LINE-1 Identifies Motifs Essential for Function

por Adney, Emily M., Ochmann, Matthias T., Sil, Srinjoy, Truong, David M., Mita, Paolo, Wang, Xuya, Kahler, David J., Fenyö, David, Holt, Liam J., Boeke, Jef D.
Publicado 2019

Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence

por Neurohr, Gabriel E., Terry, Rachel L., Lengefeld, Jette, Bonney, Megan, Brittingham, Gregory P., Moretto, Fabien, Miettinen, Teemu P., Vaites, Laura Pontano, Soares, Luis M., Paulo, Joao A., Harper, J. Wade, Buratowski, Stephen, Manalis, Scott, van Werven, Folkert J., Holt, Liam J., Amon, Angelika
Publicado 2019

Z-α(1)-antitrypsin polymers impose molecular filtration in the endoplasmic reticulum after undergoing phase transition to a solid state

por Chambers, Joseph E., Zubkov, Nikita, Kubánková, Markéta, Nixon-Abell, Jonathon, Mela, Ioanna, Abreu, Susana, Schwiening, Max, Lavarda, Giulia, López-Duarte, Ismael, Dickens, Jennifer A., Torres, Tomás, Kaminski, Clemens F., Holt, Liam J., Avezov, Edward, Huntington, James A., George-Hyslop, Peter St, Kuimova, Marina K., Marciniak, Stefan J.
Publicado 2022