A novel drug for uncomplicated malaria: targeted high throughput screening (HTS) against the type II NADH:ubiquinone oxidoreductase (PfNdh2) of Plasmodium falciparum

por Ward, Steve A, Fisher, Nicholas, Hill, Alasdair, Mbekeani, Alison, Shone, Alison, Nixon, Gemma, Stocks, Paul, Gibbons, Peter, Amewu, Richard, Hong, David W, Barton, Victoria, Pidathala, Chandra, Chadwick, James, Le Pensee, Louise, Warman, Ashley, Sharma, Raman, Berry, Neil G, O'Neill, Paul M, Biagini, Giancarlo A
Publicado 2010

Development of a novel drug for uncomplicated malaria targeting the mitochondrial NADH:quinone oxidoreductase

por Biagini, Giancarlo A, Hill, Alasdair, Mbekeani, Alison, Shone, Alison, Nixon, Gemma, Stocks, Paul, Gibbons, Peter, Amewu, Richard, Hong, David W, Barton, Victoria, Pidathala, Chandra, Chadwick, James, Le Pensee, Louise, Warman, Ashley, Sharma, Raman, Fisher, Nick, Berry, Neil G, O'Neill, Paul M, Ward, Steve A
Publicado 2010

Remdesivir–ivermectin combination displays synergistic interaction with improved in vitro activity against SARS-CoV-2

por Jeffreys, Laura N., Pennington, Shaun H., Duggan, Jack, Caygill, Claire H., Lopeman, Rose C., Breen, Alastair F., Jinks, Jessica B., Ardrey, Alison, Donnellan, Samantha, Patterson, Edward I., Hughes, Grant L., Hong, David W., O'Neill, Paul M., Aljayyoussi, Ghaith, Owen, Andrew, Ward, Stephen A., Biagini, Giancarlo A.
Publicado 2022

Identification of Novel Antimalarial Chemotypes via Chemoinformatic Compound Selection Methods for a High-Throughput Screening Program against the Novel Malarial Target, PfNDH2: In...

por Sharma, Raman, Lawrenson, Alexandre S., Fisher, Nicholas E., Warman, Ashley J., Shone, Alison E., Hill, Alasdair, Mbekeani, Alison, Pidathala, Chandrakala, Amewu, Richard K., Leung, Suet, Gibbons, Peter, Hong, David W., Stocks, Paul, Nixon, Gemma L., Chadwick, James, Shearer, Joanne, Gowers, Ian, Cronk, David, Parel, Serge P., O'Neill, Paul M., Ward, Stephen A., Biagini, Giancarlo A., Berry, Neil G.
Publicado 2012