Alternative Complement Pathway Inhibition by Lampalizumab: Analysis of Data From Chroma and Spectri Phase III Clinical Trials

por Edmonds, Rose, Steffen, Verena, Honigberg, Lee A., Chang, Michael C.
Publicado 2023

The Role of the Complement Pathway in Clinical Progression of Geographic Atrophy: Analysis of the Phase III Chroma and Spectri Trials

por Edmonds, Rose, Steffen, Verena, Honigberg, Lee A., Chang, Michael C.
Publicado 2023

Preanalytical approaches to improve recovery of amyloid-β peptides from CSF as measured by immunological or mass spectrometry-based assays

por Schauer, Stephen P., Mylott, William R., Yuan, Moucun, Jenkins, Rand G., Rodney Mathews, W., Honigberg, Lee A., Wildsmith, Kristin R.
Publicado 2018

Identification of longitudinally dynamic biomarkers in Alzheimer’s disease cerebrospinal fluid by targeted proteomics

por Wildsmith, Kristin R, Schauer, Stephen P, Smith, Ashley M, Arnott, David, Zhu, Yuda, Haznedar, Joshua, Kaur, Surinder, Mathews, W Rodney, Honigberg, Lee A
Publicado 2014

ABBY: A phase 2 randomized trial of crenezumab in mild to moderate Alzheimer disease

por Cummings, Jeffrey L., Cohen, Sharon, van Dyck, Christopher H., Brody, Mark, Curtis, Craig, Cho, William, Ward, Michael, Friesenhahn, Michel, Rabe, Christina, Brunstein, Flavia, Quartino, Angelica, Honigberg, Lee A., Fuji, Reina N., Clayton, David, Mortensen, Deborah, Ho, Carole, Paul, Robert
Publicado 2018

Amyloid positron emission tomography and cerebrospinal fluid results from a crenezumab anti-amyloid-beta antibody double-blind, placebo-controlled, randomized phase II study in mil...

por Salloway, Stephen, Honigberg, Lee A., Cho, William, Ward, Michael, Friesenhahn, Michel, Brunstein, Flavia, Quartino, Angelica, Clayton, David, Mortensen, Deborah, Bittner, Tobias, Ho, Carole, Rabe, Christina, Schauer, Stephen P., Wildsmith, Kristin R., Fuji, Reina N., Suliman, Shehnaaz, Reiman, Eric M., Chen, Kewei, Paul, Robert
Publicado 2018

Evaluating the Safety and Efficacy of Crenezumab vs Placebo in Adults With Early Alzheimer Disease: Two Phase 3 Randomized Placebo-Controlled Trials

por Ostrowitzki, Susanne, Bittner, Tobias, Sink, Kaycee M., Mackey, Howard, Rabe, Christina, Honig, Lawrence S., Cassetta, Emanuele, Woodward, Michael, Boada, Mercè, van Dyck, Christopher H., Grimmer, Timo, Selkoe, Dennis J., Schneider, Andres, Blondeau, Kathleen, Hu, Nan, Quartino, Angelica, Clayton, David, Dolton, Michael, Dang, Yifan, Ostaszewski, Beth, Sanabria-Bohórquez, Sandra M., Rabbia, Michael, Toth, Balazs, Eichenlaub, Udo, Smith, Jillian, Honigberg, Lee A., Doody, Rachelle S.
Publicado 2022