Two successful decades of Swiss collaborations to develop new anti-malarials

por Hooft van Huijsduijnen, Rob, Wells, Timothy, Tanner, Marcel, Wittlin, Sergio
Publicado 2019

Designing the next generation of medicines for malaria control and eradication

por Burrows, Jeremy N, Hooft van Huijsduijnen, Rob, Möhrle, Jörg J, Oeuvray, Claude, Wells, Timothy NC
Publicado 2013

Efficacy of OZ439 (artefenomel) against early Plasmodium falciparum blood-stage malaria infection in healthy volunteers

por McCarthy, James S., Baker, Mark, O'Rourke, Peter, Marquart, Louise, Griffin, Paul, Hooft van Huijsduijnen, Rob, Möhrle, Jörg J.
Publicado 2016

Reassessing therapeutic antibodies for neglected and tropical diseases

por Hooft van Huijsduijnen, Rob, Kojima, Somei, Carter, Dee, Okabe, Hisafumi, Sato, Akihide, Akahata, Wataru, Wells, Timothy N. C., Katsuno, Kei
Publicado 2020

Protein tyrosine phosphatases in glioma biology

por Navis, Anna C., van den Eijnden, Monique, Schepens, Jan T. G., Hooft van Huijsduijnen, Rob, Wesseling, Pieter, Hendriks, Wiljan J. A. J.
Publicado 2009

A discovery and development roadmap for new endectocidal transmission-blocking agents in malaria

por Burrows, Jeremy, Slater, Hannah, Macintyre, Fiona, Rees, Sarah, Thomas, Anna, Okumu, Fredros, Hooft van Huijsduijnen, Rob, Duparc, Stephan, Wells, Timothy N. C.
Publicado 2018

New developments in anti-malarial target candidate and product profiles

por Burrows, Jeremy N., Duparc, Stephan, Gutteridge, Winston E., Hooft van Huijsduijnen, Rob, Kaszubska, Wiweka, Macintyre, Fiona, Mazzuri, Sébastien, Möhrle, Jörg J., Wells, Timothy N. C.
Publicado 2017

Anticancer Properties of Distinct Antimalarial Drug Classes

por Hooft van Huijsduijnen, Rob, Guy, R. Kiplin, Chibale, Kelly, Haynes, Richard K., Peitz, Ingmar, Kelter, Gerhard, Phillips, Margaret A., Vennerstrom, Jonathan L., Yuthavong, Yongyuth, Wells, Timothy N. C.
Publicado 2013

A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study

por McCarthy, James S., Rückle, Thomas, Djeriou, Elhadj, Cantalloube, Cathy, Ter-Minassian, Daniel, Baker, Mark, O’Rourke, Peter, Griffin, Paul, Marquart, Louise, Hooft van Huijsduijnen, Rob, Möhrle, Jörg J.
Publicado 2016

Injectable anti-malarials revisited: discovery and development of new agents to protect against malaria

por Macintyre, Fiona, Ramachandruni, Hanu, Burrows, Jeremy N., Holm, René, Thomas, Anna, Möhrle, Jörg J., Duparc, Stephan, Hooft van Huijsduijnen, Rob, Greenwood, Brian, Gutteridge, Winston E., Wells, Timothy N. C., Kaszubska, Wiweka
Publicado 2018

The Pandemic Response Box—Accelerating Drug Discovery Efforts after Disease Outbreaks

por Samby, Kirandeep, Besson, Dominique, Dutta, Anirban, Patra, Buddhadev, Doy, Angelique, Glossop, Paul, Mills, James, Whitlock, Gavin, Hooft van Huijsduijnen, Rob, Monaco, Alessandra, Bilbe, Graeme, Mowbray, Charles, Perry, Benjamin, Adam, Anna, Wells, Timothy N. C., Willis, Paul A.
Publicado 2022

Comprehensive protein tyrosine phosphatase mRNA profiling identifies new regulators in the progression of glioma

por Bourgonje, Annika M., Verrijp, Kiek, Schepens, Jan T. G., Navis, Anna C., Piepers, Jolanda A. F., Palmen, Chantal B. C., van den Eijnden, Monique, Hooft van Huijsduijnen, Rob, Wesseling, Pieter, Leenders, William P. J., Hendriks, Wiljan J. A. J.
Publicado 2016

Multidrug-resistant gonorrhea: A research and development roadmap to discover new medicines

por Alirol, Emilie, Wi, Teodora E., Bala, Manju, Bazzo, Maria Luiza, Chen, Xiang-Sheng, Deal, Carolyn, Dillon, Jo-Anne R., Kularatne, Ranmini, Heim, Jutta, Hooft van Huijsduijnen, Rob, Hook, Edward W., Lahra, Monica M., Lewis, David A., Ndowa, Francis, Shafer, William M., Tayler, Liz, Workowski, Kimberly, Unemo, Magnus, Balasegaram, Manica
Publicado 2017

Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax mal...

por Llanos-Cuentas, Alejandro, Casapia, Martin, Chuquiyauri, Raúl, Hinojosa, Juan-Carlos, Kerr, Nicola, Rosario, Maria, Toovey, Stephen, Arch, Robert H, Phillips, Margaret A, Rozenberg, Felix D, Bath, Jade, Ng, Caroline L, Cowell, Annie N, Winzeler, Elizabeth A, Fidock, David A, Baker, Mark, Möhrle, Jörg J, Hooft van Huijsduijnen, Rob, Gobeau, Nathalie, Araeipour, Nada, Andenmatten, Nicole, Rückle, Thomas, Duparc, Stephan
Publicado 2018

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

por Van Voorhis, Wesley C., Adams, John H., Adelfio, Roberto, Ahyong, Vida, Akabas, Myles H., Alano, Pietro, Alday, Aintzane, Alemán Resto, Yesmalie, Alsibaee, Aishah, Alzualde, Ainhoa, Andrews, Katherine T., Avery, Simon V., Avery, Vicky M., Ayong, Lawrence, Baker, Mark, Baker, Stephen, Ben Mamoun, Choukri, Bhatia, Sangeeta, Bickle, Quentin, Bounaadja, Lotfi, Bowling, Tana, Bosch, Jürgen, Boucher, Lauren E., Boyom, Fabrice F., Brea, Jose, Brennan, Marian, Burton, Audrey, Caffrey, Conor R., Camarda, Grazia, Carrasquilla, Manuela, Carter, Dee, Belen Cassera, Maria, Chih-Chien Cheng, Ken, Chindaudomsate, Worathad, Chubb, Anthony, Colon, Beatrice L., Colón-López, Daisy D., Corbett, Yolanda, Crowther, Gregory J., Cowan, Noemi, D’Alessandro, Sarah, Le Dang, Na, Delves, Michael, DeRisi, Joseph L., Du, Alan Y., Duffy, Sandra, Abd El-Salam El-Sayed, Shimaa, Ferdig, Michael T., Fernández Robledo, José A., Fidock, David A., Florent, Isabelle, Fokou, Patrick V. T., Galstian, Ani, Gamo, Francisco Javier, Gokool, Suzanne, Gold, Ben, Golub, Todd, Goldgof, Gregory M., Guha, Rajarshi, Guiguemde, W. Armand, Gural, Nil, Guy, R. Kiplin, Hansen, Michael A. E., Hanson, Kirsten K., Hemphill, Andrew, Hooft van Huijsduijnen, Rob, Horii, Takaaki, Horrocks, Paul, Hughes, Tyler B., Huston, Christopher, Igarashi, Ikuo, Ingram-Sieber, Katrin, Itoe, Maurice A., Jadhav, Ajit, Naranuntarat Jensen, Amornrat, Jensen, Laran T., Jiang, Rays H. Y., Kaiser, Annette, Keiser, Jennifer, Ketas, Thomas, Kicka, Sebastien, Kim, Sunyoung, Kirk, Kiaran, Kumar, Vidya P., Kyle, Dennis E., Lafuente, Maria Jose, Landfear, Scott, Lee, Nathan, Lee, Sukjun, Lehane, Adele M., Li, Fengwu, Little, David, Liu, Liqiong, Llinás, Manuel, Loza, Maria I., Lubar, Aristea, Lucantoni, Leonardo, Lucet, Isabelle, Maes, Louis, Mancama, Dalu, Mansour, Nuha R., March, Sandra, McGowan, Sheena, Medina Vera, Iset, Meister, Stephan, Mercer, Luke, Mestres, Jordi, Mfopa, Alvine N., Misra, Raj N., Moon, Seunghyun, Moore, John P., Morais Rodrigues da Costa, Francielly, Müller, Joachim, Muriana, Arantza, Nakazawa Hewitt, Stephen, Nare, Bakela, Nathan, Carl, Narraidoo, Nathalie, Nawaratna, Sujeevi, Ojo, Kayode K., Ortiz, Diana, Panic, Gordana, Papadatos, George, Parapini, Silvia, Patra, Kailash, Pham, Ngoc, Prats, Sarah, Plouffe, David M., Poulsen, Sally-Ann, Pradhan, Anupam, Quevedo, Celia, Quinn, Ronald J., Rice, Christopher A., Abdo Rizk, Mohamed, Ruecker, Andrea, St. Onge, Robert, Salgado Ferreira, Rafaela, Samra, Jasmeet, Robinett, Natalie G., Schlecht, Ulrich, Schmitt, Marjorie, Silva Villela, Filipe, Silvestrini, Francesco, Sinden, Robert, Smith, Dennis A., Soldati, Thierry, Spitzmüller, Andreas, Stamm, Serge Maximilian, Sullivan, David J., Sullivan, William, Suresh, Sundari, Suzuki, Brian M., Suzuki, Yo, Swamidass, S. Joshua, Taramelli, Donatella, Tchokouaha, Lauve R. Y., Theron, Anjo, Thomas, David, Tonissen, Kathryn F., Townson, Simon, Tripathi, Abhai K., Trofimov, Valentin, Udenze, Kenneth O., Ullah, Imran, Vallieres, Cindy, Vigil, Edgar, Vinetz, Joseph M., Voong Vinh, Phat, Vu, Hoan, Watanabe, Nao-aki, Weatherby, Kate, White, Pamela M., Wilks, Andrew F., Winzeler, Elizabeth A., Wojcik, Edward, Wree, Melanie, Wu, Wesley, Yokoyama, Naoaki, Zollo, Paul H. A., Abla, Nada, Blasco, Benjamin, Burrows, Jeremy, Laleu, Benoît, Leroy, Didier, Spangenberg, Thomas, Wells, Timothy, Willis, Paul A.
Publicado 2016