Human induced pluripotent stem cell–derived liver-on-a-chip for studying drug metabolism: the challenge of the cytochrome P450 family

por Tamargo-Rubio, Isabel, Simpson, Anna Bella, Hoogerland, Joanne A., Fu, Jingyuan
Publicado 2023

Glycogen storage disease type 1a is associated with disturbed vitamin A metabolism and elevated serum retinol levels

por Saeed, Ali, Hoogerland, Joanne A, Wessel, Hanna, Heegsma, Janette, Derks, Terry G J, van der Veer, Eveline, Mithieux, Gilles, Rajas, Fabienne, Oosterveer, Maaike H, Faber, Klaas Nico
Publicado 2020

Genetic deletion of hepatic NCOR1 protects from atherosclerosis by promoting alternative bile acid-metabolism and sterol excretion

por Geiger, Martin, Oppi, Sara, Nusser-Stein, Stefanie, Costantino, Sarah, Mohammed, Shafeeq Ahmed, Gorica, Era, Hoogerland, Joanne A., Matter, Christian M., Guillaumon, Ana T., Ruschitzka, Frank, Paneni, Francesco, Oosterveer, Maaike H., Stein, Sokrates
Publicado 2023

Hepatic Carbohydrate Response Element Binding Protein Activation Limits Nonalcoholic Fatty Liver Disease Development in a Mouse Model for Glycogen Storage Disease Type 1a

por Lei, Yu, Hoogerland, Joanne A., Bloks, Vincent W., Bos, Trijnie, Bleeker, Aycha, Wolters, Henk, Wolters, Justina C., Hijmans, Brenda S., van Dijk, Theo H., Thomas, Rachel, van Weeghel, Michel, Mithieux, Gilles, Houtkooper, Riekelt H., de Bruin, Alain, Rajas, Fabienne, Kuipers, Folkert, Oosterveer, Maaike H.
Publicado 2020

Glucose‐6‐Phosphate Regulates Hepatic Bile Acid Synthesis in Mice

por Hoogerland, Joanne A., Lei, Yu, Wolters, Justina C., de Boer, Jan Freark, Bos, Trijnie, Bleeker, Aycha, Mulder, Niels L., van Dijk, Theo H., Kuivenhoven, Jan A., Rajas, Fabienne, Mithieux, Gilles, Haeusler, Rebecca A., Verkade, Henkjan J., Bloks, Vincent W., Kuipers, Folkert, Oosterveer, Maaike H.
Publicado 2019

Hepatocyte-specific glucose-6-phosphatase deficiency disturbs platelet aggregation and decreases blood monocytes upon fasting-induced hypoglycemia

por La Rose, Anouk M., Bazioti, Venetia, Hoogerland, Joanne A., Svendsen, Arthur F., Groenen, Anouk G., van Faassen, Martijn, Rutten, Martijn G.S., Kloosterhuis, Niels J., Dethmers-Ausema, Bertien, Nijland, J. Hendrik, Mithieux, Gilles, Rajas, Fabienne, Kuipers, Folkert, Lukens, Michaël V., Soehnlein, Oliver, Oosterveer, Maaike H., Westerterp, Marit
Publicado 2021

Supplementation with Lactobacillus plantarum WCFS1 Prevents Decline of Mucus Barrier in Colon of Accelerated Aging Ercc1(−/Δ7) Mice

por van Beek, Adriaan A., Sovran, Bruno, Hugenholtz, Floor, Meijer, Ben, Hoogerland, Joanne A., Mihailova, Violeta, van der Ploeg, Corine, Belzer, Clara, Boekschoten, Mark V., Hoeijmakers, Jan H. J., Vermeij, Wilbert P., de Vos, Paul, Wells, Jerry M., Leenen, Pieter J. M., Nicoletti, Claudio, Hendriks, Rudi W., Savelkoul, Huub F. J.
Publicado 2016

Impaired Very‐Low‐Density Lipoprotein catabolism links hypoglycemia to hypertriglyceridemia in Glycogen Storage Disease type Ia

por Hoogerland, Joanne A., Peeks, Fabian, Hijmans, Brenda S., Wolters, Justina C., Kooijman, Sander, Bos, Trijnie, Bleeker, Aycha, van Dijk, Theo H., Wolters, Henk, Gerding, Albert, van Eunen, Karen, Havinga, Rick, Pronk, Amanda C. M., Rensen, Patrick C. N., Mithieux, Gilles, Rajas, Fabienne, Kuipers, Folkert, Reijngoud, Dirk‐Jan, Derks, Terry G. J., Oosterveer, Maaike H.
Publicado 2021

Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic Acid

por de Boer, Jan Freark, de Vries, Hilde D., Palmiotti, Anna, Li, Rumei, Doestzada, Marwah, Hoogerland, Joanne A., Fu, Jingyuan, La Rose, Anouk M., Westerterp, Marit, Mulder, Niels L., Hovingh, Milaine V., Koehorst, Martijn, Kloosterhuis, Niels J., Wolters, Justina C., Bloks, Vincent W., Haas, Joel T., Dombrowicz, David, Staels, Bart, van de Sluis, Bart, Kuipers, Folkert
Publicado 2020