Quantitative systems pharmacology modeling provides insight into inter‐mouse variability of Anti‐CTLA4 response

por Qiao, Wenlian, Lin, Lin, Young, Carissa, Narula, Jatin, Hua, Fei, Matteson, Andrew, Hooper, Andrea, Gruenbaum, Lore, Betts, Alison
Publicado 2022

Elevated serum IgA following vaccination against SARS-CoV-2 in a cohort of high-risk first responders

por Montague, Brian T., Wipperman, Matthew F., Chio, Erica, Crow, Rowena, Hooper, Andrea T., O’Brien, Meagan P., Simões, Eric A. F.
Publicado 2022

Impaired Endothelial Progenitor Cell Mobilization and Dysfunctional Bone Marrow Stroma in Diabetes Mellitus

por Westerweel, Peter E., Teraa, Martin, Rafii, Shahin, Jaspers, Janneke E., White, Ian A., Hooper, Andrea T., Doevendans, Pieter A., Verhaar, Marianne C.
Publicado 2013

Active Immunization Against the Vascular Endothelial Growth Factor Receptor flk1 Inhibits Tumor Angiogenesis and Metastasis

por Li, Yiwen, Wang, Mei-Nai, Li, Hongli, King, Karen D., Bassi, Rajiv, Sun, Haijun, Santiago, Angel, Hooper, Andrea T., Bohlen, Peter, Hicklin, Daniel J.
Publicado 2002

A Translational Quantitative Systems Pharmacology Model for CD3 Bispecific Molecules: Application to Quantify T Cell-Mediated Tumor Cell Killing by P-Cadherin LP DART(®)

por Betts, Alison, Haddish-Berhane, Nahor, Shah, Dhaval K., van der Graaf, Piet H., Barletta, Frank, King, Lindsay, Clark, Tracey, Kamperschroer, Cris, Root, Adam, Hooper, Andrea, Chen, Xiaoying
Publicado 2019

Casirivimab + imdevimab accelerates symptom resolution linked to improved COVID-19 outcomes across susceptible antibody and risk profiles

por Li, Dateng, Xu, Meng, Hooper, Andrea T., Rofail, Diana, Mohammadi, Kusha A., Chen, Yiziying, Ali, Shazia, Norton, Thomas, Weinreich, David M., Musser, Bret J., Hamilton, Jennifer D., Geba, Gregory P.
Publicado 2023

A Phase 1 Dose-Escalation Study of PF-06671008, a Bispecific T-Cell-Engaging Therapy Targeting P-Cadherin in Patients With Advanced Solid Tumors

por Harding, James J., Garrido-Laguna, Ignacio, Chen, Xiaoying, Basu, Cynthia, Dowlati, Afshin, Forgie, Alison, Hooper, Andrea T., Kamperschroer, Cris, Max, Steven I., Moreau, Allison, Shannon, Megan, Wong, Gilbert Y., Hong, David S.
Publicado 2022

Comparison of the molecular and cellular phenotypes of common mouse syngeneic models with human tumors

por Zhong, Wenyan, Myers, Jeremy S., Wang, Fang, Wang, Kai, Lucas, Justin, Rosfjord, Edward, Lucas, Judy, Hooper, Andrea T., Yang, Sharon, Lemon, Lu Anna, Guffroy, Magali, May, Chad, Bienkowska, Jadwiga R., Rejto, Paul A.
Publicado 2020

Casirivimab and Imdevimab Treatment Reduces Viral Load and Improves Clinical Outcomes in Seropositive Hospitalized COVID-19 Patients with Nonneutralizing or Borderline Neutralizing...

por Hooper, Andrea T., Somersan-Karakaya, Selin, McCarthy, Shane E., Mylonakis, Eleftherios, Ali, Shazia, Mei, Jingning, Bhore, Rafia, Mahmood, Adnan, Geba, Gregory P., Dakin, Paula, Weinreich, David M., Yancopoulos, George D., Herman, Gary A., Hamilton, Jennifer D.
Publicado 2022

Seroprevalence of anti-SARS-CoV-2 antibodies in a cohort of New York City metro blood donors using multiple SARS-CoV-2 serological assays: Implications for controlling the epidemic...

por Jin, Daniel K., Nesbitt, Daniel J., Yang, Jenny, Chen, Haidee, Horowitz, Julie, Jones, Marcus, Vandergaast, Rianna, Carey, Timothy, Reiter, Samantha, Russell, Stephen J., Kyratsous, Christos, Hooper, Andrea, Hamilton, Jennifer, Ferreira, Manuel, Deng, Sarah, Straus, Donna, Baras, Aris, Hillyer, Christopher D., Luchsinger, Larry L.
Publicado 2021

Effectiveness of Casirivimab and Imdevimab Antibody Combination in Immunocompromised Hospitalized Patients With Coronavirus Disease 2019: A Post Hoc Analysis in a Phase 1/2/3 Doubl...

por Somersan-Karakaya, Selin, Mylonakis, Eleftherios, Mou, Jenni, Oviedo-Orta, Ernesto, O’Brien, Meagan P, Mas Casullo, Veronica, Mahmood, Adnan, Hooper, Andrea T, Hussein, Mohamed, Ali, Shazia, Marty, Francisco M, Forleo-Neto, Eduardo, Bhore, Rafia, Hamilton, Jennifer D, Herman, Gary A, Hirshberg, Boaz, Weinreich, David M
Publicado 2023

Anti-Extra Domain B Splice Variant of Fibronectin Antibody–Drug Conjugate Eliminates Tumors with Enhanced Efficacy When Combined with Checkpoint Blockade

por Hooper, Andrea T., Marquette, Kimberly, Chang, Chao-Pei Betty, Golas, Jonathon, Jain, Sadhana, Lam, My-Hanh, Guffroy, Magali, Leal, Mauricio, Falahatpisheh, Hadi, Mathur, Divya, Chen, Ting, Kelleher, Kerry, Khandke, Kiran, Muszynska, Elwira, Loganzo, Frank, Rosfjord, Edward, Lucas, Judy, Kan, Zhengyan, Subramanyam, Chakrapani, O'Donnell, Christopher, Neri, Dario, Gerber, Hans-Peter, May, Chad, Sapra, Puja
Publicado 2022

Examining protective effects of SARS-CoV-2 neutralizing antibodies after vaccination or monoclonal antibody administration

por Follmann, Dean, O’Brien, Meagan P., Fintzi, Jonathan, Fay, Michael P., Montefiori, David, Mateja, Allyson, Herman, Gary A., Hooper, Andrea T., Turner, Kenneth C., Chan, Kuo- Chen, Forleo-Neto, Eduardo, Isa, Flonza, Baden, Lindsey R., El Sahly, Hana M., Janes, Holly, Doria-Rose, Nicole, Miller, Jacqueline, Zhou, Honghong, Dang, Weiping, Benkeser, David, Fong, Youyi, Gilbert, Peter B., Marovich, Mary, Cohen, Myron S.
Publicado 2023

Repeat subcutaneous administration of casirivimab and imdevimab in adults is well-tolerated and prevents the occurrence of COVID-19

por Isa, Flonza, Forleo-Neto, Eduardo, Meyer, Jonathan, Zheng, Wenjun, Rasmussen, Scott, Armas, Danielle, Oshita, Masaru, Brinson, Cynthia, Folkerth, Steven, Faria, Lori, Heirman, Ingeborg, Sarkar, Neena, Musser, Bret J., Bansal, Shikha, O'Brien, Meagan P., Turner, Kenneth C., Ganguly, Samit, Mahmood, Adnan, Dupljak, Ajla, Hooper, Andrea T., Hamilton, Jennifer D., Kim, Yunji, Kowal, Bari, Soo, Yuhwen, Geba, Gregory P., Lipsich, Leah, Braunstein, Ned, Yancopoulos, George D., Weinreich, David M., Herman, Gary A.
Publicado 2022

Virologic Efficacy of Casirivimab and Imdevimab COVID-19 Antibody Combination in Outpatients With SARS-CoV-2 Infection: A Phase 2 Dose-Ranging Randomized Clinical Trial

por Portal-Celhay, Cynthia, Forleo-Neto, Eduardo, Eagan, Will, Musser, Bret J., Davis, John D., Turner, Kenneth C., Norton, Thomas, Hooper, Andrea T., Hamilton, Jennifer D., Pan, Cynthia, Mahmood, Adnan, Baum, Alina, Kyratsous, Christos A., Kim, Yunji, Parrino, Janie, Kampman, Wendy, Roque-Guerrero, Lilia, Stoici, Roxana, Fatakia, Adil, Soo, Yuhwen, Geba, Gregory P., Kowal, Bari, DiCioccio, A. Thomas, Stahl, Neil, Lipsich, Leah, Braunstein, Ned, Herman, Gary A., Yancopoulos, George D., Weinreich, David M.
Publicado 2022

REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with Covid-19

por Weinreich, David M., Sivapalasingam, Sumathi, Norton, Thomas, Ali, Shazia, Gao, Haitao, Bhore, Rafia, Musser, Bret J., Soo, Yuhwen, Rofail, Diana, Im, Joseph, Perry, Christina, Pan, Cynthia, Hosain, Romana, Mahmood, Adnan, Davis, John D., Turner, Kenneth C., Hooper, Andrea T., Hamilton, Jennifer D., Baum, Alina, Kyratsous, Christos A., Kim, Yunji, Cook, Amanda, Kampman, Wendy, Kohli, Anita, Sachdeva, Yessica, Graber, Ximena, Kowal, Bari, DiCioccio, Thomas, Stahl, Neil, Lipsich, Leah, Braunstein, Ned, Herman, Gary, Yancopoulos, George D.
Publicado 2020

LB4. Casirivimab and Imdevimab for Treatment of Hospitalized Patients With COVID-19 Receiving Low Flow or No Supplemental Oxygen

por Mylonakis, Eleftherios, Somersan-Karakaya, Selin, Sivapalasingam, Sumathi, Ali, Shazia, Sun, Yiping, Bhore, Rafia, Mei, Jingning, Miller, Jutta, Cupelli, Lisa, Hooper, Andrea T, Hamilton, Jennifer D, Pan, Cynthia, Pham, Viet, Zhao, Yuming, Hosain, Romana, Mahmood, Adnan, Davis, John D, Turner, Kenneth C, Kim, Yunji, Cook, Amanda, Menon, Vidya, Wells, Jason C, Kowal, Bari, Soo, Yuhwen, DiCioccio, A Thomas, Geba, Gregory P, Stahl, Neil, Lipsich, Leah, Braunstein, Ned, Herman, Gary, Yancopoulos, George D, Weinreich, David M
Publicado 2021

Efficacy and safety of a single dose of casirivimab and imdevimab for the prevention of COVID-19 over an 8-month period: a randomised, double-blind, placebo-controlled trial

por Herman, Gary A, O'Brien, Meagan P, Forleo-Neto, Eduardo, Sarkar, Neena, Isa, Flonza, Hou, Peijie, Chan, Kuo-Chen, Bar, Katharine J, Barnabas, Ruanne V, Barouch, Dan H, Cohen, Myron S, Hurt, Christopher B, Burwen, Dale R, Marovich, Mary A, Musser, Bret J, Davis, John D, Turner, Kenneth C, Mahmood, Adnan, Hooper, Andrea T, Hamilton, Jennifer D, Parrino, Janie, Subramaniam, Danise, Baum, Alina, Kyratsous, Christos A, DiCioccio, A Thomas, Stahl, Neil, Braunstein, Ned, Yancopoulos, George D, Weinreich, David M
Publicado 2022

Casirivimab and Imdevimab for the Treatment of Hospitalized Patients With COVID-19

por Somersan-Karakaya, Selin, Mylonakis, Eleftherios, Menon, Vidya P, Wells, Jason C, Ali, Shazia, Sivapalasingam, Sumathi, Sun, Yiping, Bhore, Rafia, Mei, Jingning, Miller, Jutta, Cupelli, Lisa, Forleo-Neto, Eduardo, Hooper, Andrea T, Hamilton, Jennifer D, Pan, Cynthia, Pham, Viet, Zhao, Yuming, Hosain, Romana, Mahmood, Adnan, Davis, John D, Turner, Kenneth C, Kim, Yunji, Cook, Amanda, Kowal, Bari, Soo, Yuhwen, DiCioccio, A Thomas, Geba, Gregory P, Stahl, Neil, Lipsich, Leah, Braunstein, Ned, Herman, Gary A, Yancopoulos, George D, Weinreich, David M
Publicado 2022

The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies

por Copin, Richard, Baum, Alina, Wloga, Elzbieta, Pascal, Kristen E., Giordano, Stephanie, Fulton, Benjamin O., Zhou, Anbo, Negron, Nicole, Lanza, Kathryn, Chan, Newton, Coppola, Angel, Chiu, Joyce, Ni, Min, Wei, Yi, Atwal, Gurinder S., Hernandez, Annabel Romero, Saotome, Kei, Zhou, Yi, Franklin, Matthew C., Hooper, Andrea T., McCarthy, Shane, Hamon, Sara, Hamilton, Jennifer D., Staples, Hilary M., Alfson, Kendra, Carrion, Ricardo, Ali, Shazia, Norton, Thomas, Somersan-Karakaya, Selin, Sivapalasingam, Sumathi, Herman, Gary A., Weinreich, David M., Lipsich, Leah, Stahl, Neil, Murphy, Andrew J., Yancopoulos, George D., Kyratsous, Christos A.
Publicado 2021